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Copper-Catalyzed Domino Cycloaddition/CN Coupling/Cyclization/(CH Arylation): An Efficient Three-Component Synthesis of Nitrogen Polyheterocycles

Angewandte Chemie International Edition, 2013-10, Vol.52 (42), p.10992-10996

2013

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A new wave of innovations within the DNA damage response

Signal transduction and targeted therapy, 2023-09, Vol.8 (1), p.338-26, Article 338

2023

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A “Click and Activate” Approach in One-Pot Synthesis of a Triazolyl-Pyridazinone Library

Organic letters, 2011-04, Vol.13 (7), p.1682-1685

2011

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One-pot synthesis of [1,2,3]triazole-fused pyrazinopyridazindione tricycles by a ‘click and activate’ approach

Tetrahedron letters, 2012-01, Vol.53 (3), p.271-274

2012

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Convergent, Regioselective Synthesis of Tetrakisfulleroids from C60

Journal of organic chemistry, 2002-11, Vol.67 (22), p.7683-7687

2002

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Discovery of dihydroquinoxalinone acetamides containing bicyclic amines as potent Bradykinin B1 receptor antagonists

Bioorganic & medicinal chemistry, 2008-08, Vol.18 (16), p.4477-4481

2008

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Total Synthesis and Structural Elucidation of Azaspiracid-1. Construction of Key Building Blocks for Originally Proposed Structure

Journal of the American Chemical Society, 2006-02, Vol.128 (7), p.2244-2257

2006

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Total Synthesis of the Proposed Azaspiracid-1 Structure, Part 1: Construction of the Enantiomerically Pure C1-C20, C21-C27, and C28-C40 Fragments

Angewandte Chemie International Edition, 2003-08, Vol.42 (31), p.3643-3648

2003

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Towards Sixfold Functionalization of Buckminsterfullerene (C60) at Fully Addressable Octahedral Sites

Angewandte Chemie International Edition, 1999-08, Vol.38 (16), p.2356-2360

1999

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Discovery of dehydro-oxopiperazine acetamides as novel bradykinin B1 receptor antagonists with enhanced in vitro potency

Bioorganic & medicinal chemistry letters, 2012-01, Vol.22 (2), p.1061-1067

2012

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Synthesis of Stable Derivatives of C62: The First Nonclassical Fullerene Incorporating a Four-Membered Ring

Journal of the American Chemical Society, 2003-02, Vol.125 (8), p.2066-2067

2003

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One-Pot Synthesis of 3‑Triazolyl-2-iminochromenes via a Catalytic Three Component Cascade Reaction

Organic letters, 2013-06, Vol.15 (12), p.2986-2989

2013

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Copper-Catalyzed Domino Cycloaddition/CN Coupling/Cyclization/(CH Arylation): An Efficient Three-Component Synthesis of Nitrogen Polyheterocycles

Angewandte Chemie, 2013-10, Vol.125 (42), p.11198-11202

2013

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Identification of TUL01101: A Novel Potent and Selective JAK1 Inhibitor for the Treatment of Rheumatoid Arthritis

Journal of medicinal chemistry, 2022-12, Vol.65 (24), p.16716-16740

2022

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3-Oxo-2-piperazinyl acetamides as potent bradykinin B1 receptor antagonists for the treatment of pain and inflammation

Bioorganic & medicinal chemistry letters, 2011-06, Vol.21 (11), p.3384-3389

2011

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Aryl sulfones as novel Bradykinin B1 receptor antagonists for treatment of chronic pain

Bioorganic & medicinal chemistry, 2008-09, Vol.18 (17), p.4764-4769

2008

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Aryl sulfonamides containing tetralin allylic amines as potent and selective bradykinin B1 receptor antagonists

Bioorganic & medicinal chemistry letters, 2010-08, Vol.20 (15), p.4593-4597

2010

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Accelerating Effect of Triazolyl and Related Heteroaryl Substituents on S N Ar Reactions: Evidence of Hydrogen-Bond Stabilized Transition States

Journal of the American Chemical Society, 2015-09, Vol.137 (38), p.12261-12268

2015

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Synthesis and evaluation of hydrazinyl-containing pyrrolo[2,3-d]pyrimidine series as potent, selective and oral JAK1 inhibitors for the treatment of rheumatoid arthritis

Bioorganic & medicinal chemistry letters, 2022-10, Vol.74, p.128905-128905, Article 128905

2022

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One-pot synthesis of 3-triazolyl-quinolin-2-(1H)-ones via sequential Ugi-“click”-Knoevenagel condensations

Tetrahedron letters, 2018-05, Vol.59 (22), p.2167-2169

2018

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Accelerating Effect of Triazolyl and Related Heteroaryl Substituents on SNAr Reactions: Evidence of Hydrogen-Bond Stabilized Transition States

Journal of the American Chemical Society, 2015-09, Vol.137 (38), p.12261-12268

2015

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Preclinical evaluation of SC0245, a small molecule inhibitor of ATR kinase

Journal of clinical oncology, 2020-05, Vol.38 (15_suppl), p.e15642-e15642

2020

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Preclinical evaluation of SC0191, a small molecule inhibitor of Wee1 kinase

Journal of clinical oncology, 2020-05, Vol.38 (15_suppl), p.e15637-e15637

2020

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Regioselective synthesis of multiply halogenated azaxanthones

Tetrahedron letters, 2014-12, Vol.55 (52), p.7229-7232

2014

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Copper-Catalyzed Domino Cycloaddition/CN Coupling/Cyclization/(CH Arylation): An Efficient Three-Component Synthesis of Nitrogen Polyheterocycles

Angewandte Chemie International Edition, 2013-10, Vol.52 (42), p.10992

International ed. in English, 2013

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Copper-Catalyzed Domino Cycloaddition/CN Coupling/Cyclization/(CH Arylation): An Efficient Three-Component Synthesis of Nitrogen Polyheterocycles

A new wave of innovations within the DNA damage response

A “Click and Activate” Approach in One-Pot Synthesis of a Triazolyl-Pyridazinone Library

One-pot synthesis of [1,2,3]triazole-fused pyrazinopyridazindione tricycles by a ‘click and activate’ approach

Convergent, Regioselective Synthesis of Tetrakisfulleroids from C60

Discovery of dihydroquinoxalinone acetamides containing bicyclic amines as potent Bradykinin B1 receptor antagonists

Total Synthesis and Structural Elucidation of Azaspiracid-1. Construction of Key Building Blocks for Originally Proposed Structure

Total Synthesis of the Proposed Azaspiracid-1 Structure, Part 1: Construction of the Enantiomerically Pure C1-C20, C21-C27, and C28-C40 Fragments

Towards Sixfold Functionalization of Buckminsterfullerene (C60) at Fully Addressable Octahedral Sites

Discovery of dehydro-oxopiperazine acetamides as novel bradykinin B1 receptor antagonists with enhanced in vitro potency

Synthesis of Stable Derivatives of C62: The First Nonclassical Fullerene Incorporating a Four-Membered Ring

One-Pot Synthesis of 3‑Triazolyl-2-iminochromenes via a Catalytic Three Component Cascade Reaction

Copper-Catalyzed Domino Cycloaddition/CN Coupling/Cyclization/(CH Arylation): An Efficient Three-Component Synthesis of Nitrogen Polyheterocycles

Identification of TUL01101: A Novel Potent and Selective JAK1 Inhibitor for the Treatment of Rheumatoid Arthritis

3-Oxo-2-piperazinyl acetamides as potent bradykinin B1 receptor antagonists for the treatment of pain and inflammation

Aryl sulfones as novel Bradykinin B1 receptor antagonists for treatment of chronic pain

Aryl sulfonamides containing tetralin allylic amines as potent and selective bradykinin B1 receptor antagonists

Accelerating Effect of Triazolyl and Related Heteroaryl Substituents on S N Ar Reactions: Evidence of Hydrogen-Bond Stabilized Transition States

Synthesis and evaluation of hydrazinyl-containing pyrrolo[2,3-d]pyrimidine series as potent, selective and oral JAK1 inhibitors for the treatment of rheumatoid arthritis

One-pot synthesis of 3-triazolyl-quinolin-2-(1H)-ones via sequential Ugi-“click”-Knoevenagel condensations

Accelerating Effect of Triazolyl and Related Heteroaryl Substituents on SNAr Reactions: Evidence of Hydrogen-Bond Stabilized Transition States

Preclinical evaluation of SC0245, a small molecule inhibitor of ATR kinase

Preclinical evaluation of SC0191, a small molecule inhibitor of Wee1 kinase

Regioselective synthesis of multiply halogenated azaxanthones

Copper-Catalyzed Domino Cycloaddition/CN Coupling/Cyclization/(CH Arylation): An Efficient Three-Component Synthesis of Nitrogen Polyheterocycles

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