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Nuclear Receptors Linking Metabolism, Inflammation, and Fibrosis in Nonalcoholic Fatty Liver Disease

International journal of molecular sciences, 2022-02, Vol.23 (5), p.2668

2022

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Myeloid cells in liver and bone marrow acquire a functionally distinct inflammatory phenotype during obesity-related steatohepatitis

Gut, 2020-03, Vol.69 (3), p.551

2020

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Differential effects of selective- and pan-PPAR agonists on experimental steatohepatitis and hepatic macrophages

Journal of hepatology, 2020-10, Vol.73 (4), p.757-770

2020

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Therapeutic inhibition of inflammatory monocyte recruitment reduces steatohepatitis and liver fibrosis

Hepatology (Baltimore, Md.), 2018-04, Vol.67 (4), p.1270-1283

2018

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Chemokine (C‐C motif) receptor 2–positive monocytes aggravate the early phase of acetaminophen‐induced acute liver injury

Hepatology (Baltimore, Md.), 2016-11, Vol.64 (5), p.1667-1682

2016

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Differential impact of the dual CCR2/CCR5 inhibitor cenicriviroc on migration of monocyte and lymphocyte subsets in acute liver injury

PloS one, 2017-09, Vol.12 (9), p.e0184694-e0184694

2017

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Serum CXCL5 Detects Early Hepatocellular Carcinoma and Indicates Tumor Progression

International journal of molecular sciences, 2023-03, Vol.24 (6), p.5295

2023

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Monocyte dysregulation: consequences for hepatic infections

Seminars in immunopathology, 2021-08, Vol.43 (4), p.493-506

2021

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Combined Therapy with a CCR2/CCR5 Antagonist and FGF21 Analogue Synergizes in Ameliorating Steatohepatitis and Fibrosis

International journal of molecular sciences, 2022-06, Vol.23 (12), p.6696

2022

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CT-based determination of excessive visceral adipose tissue is associated with an impaired survival in critically ill patients

PloS one, 2021-04, Vol.16 (4), p.e0250321-e0250321

2021

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Cell type‐specific actions of thyroid hormones in nonalcoholic steatohepatitis and liver fibrosis

Liver international, 2024-02, Vol.44 (2), p.275-278

2024

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The Medium-Chain Fatty Acid Receptor GPR84 Mediates Myeloid Cell Infiltration Promoting Steatohepatitis and Fibrosis

Journal of clinical medicine, 2020-04, Vol.9 (4), p.1140

2020

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Dissecting Acute Drug‐Induced Hepatotoxicity and Therapeutic Responses of Steatotic Liver Disease Using Primary Mouse Liver and Blood Cells in a Liver‐On‐A‐Chip Model

Advanced science, 2024-08, Vol.11 (30), p.e2403516-n/a

2024

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Efruxifermin, an investigational treatment for fibrotic or cirrhotic nonalcoholic steatohepatitis (NASH)

Expert opinion on investigational drugs, 2023-06, Vol.32 (6), p.451-461

2023

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Pharmacotherapeutic options for metabolic dysfunction-associated steatotic liver disease: where are we today?

Expert opinion on pharmacotherapy, 2024-06, Vol.25 (9), p.1249-1263

2024

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Editorial: prevalence, progression rates and mortality predictors of non‐alcoholic fatty liver disease reflected by German statutory health insurance data

Alimentary pharmacology & therapeutics, 2020-10, Vol.52 (8), p.1412-1413

2020

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Repair macrophages in acute liver failure

Gut, 2018-02, Vol.67 (2), p.202

2018

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Soluble Urokinase Plasminogen Activator Receptor Levels Are Associated with Severity of Fibrosis in Patients with Primary Sclerosing Cholangitis

Journal of clinical medicine, 2022-04, Vol.11 (9), p.2479

2022

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Cenicriviroc for the treatment of COVID-19: first interim results of a randomised, placebo-controlled, investigator-initiated, double-blind phase II trial

Journal of global antimicrobial resistance., 2023-03, Vol.32, p.44-47

2023

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An integrated view of anti-inflammatory and antifibrotic targets for the treatment of NASH

Journal of hepatology, 2023-08, Vol.79 (2), p.552-566

2023

Volltextzugriff (PDF)

Association of Serum Calprotectin Concentrations with Mortality in Critically Ill and Septic Patients

Diagnostics (Basel), 2020-11, Vol.10 (11), p.990

2020

Volltextzugriff (PDF)

Efruxifermin, an investigational treatment for fibrotic or cirrhotic non-alcoholic steatohepatitis (NASH)

Expert opinion on investigational drugs, 2023-06

2023

Volltextzugriff (PDF)

Low Serum Levels of Soluble Receptor Activator of Nuclear Factor κ B Ligand (sRANKL) Are Associated with Metabolic Dysregulation and Predict Long-Term Mortality in Critically Ill Patients

Diagnostics (Basel), 2021-12, Vol.12 (1), p.62

2021

Volltextzugriff (PDF)

THU-291-YI Cellular senescence is a common hallmark in diverse models of steatotic liver diseases

Journal of hepatology, 2024-06, Vol.80, p.S594-S595

2024

Volltextzugriff (PDF)

FRI-457 CXCL12 restricts hepatocellular carcinoma progression by shaping the tumor microenvironment in liver fibrosis

Journal of hepatology, 2024-06, Vol.80, p.S414-S414

2024

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Nuclear Receptors Linking Metabolism, Inflammation, and Fibrosis in Nonalcoholic Fatty Liver Disease

Myeloid cells in liver and bone marrow acquire a functionally distinct inflammatory phenotype during obesity-related steatohepatitis

Differential effects of selective- and pan-PPAR agonists on experimental steatohepatitis and hepatic macrophages

Therapeutic inhibition of inflammatory monocyte recruitment reduces steatohepatitis and liver fibrosis

Chemokine (C‐C motif) receptor 2–positive monocytes aggravate the early phase of acetaminophen‐induced acute liver injury

Differential impact of the dual CCR2/CCR5 inhibitor cenicriviroc on migration of monocyte and lymphocyte subsets in acute liver injury

Serum CXCL5 Detects Early Hepatocellular Carcinoma and Indicates Tumor Progression

Monocyte dysregulation: consequences for hepatic infections

Combined Therapy with a CCR2/CCR5 Antagonist and FGF21 Analogue Synergizes in Ameliorating Steatohepatitis and Fibrosis

CT-based determination of excessive visceral adipose tissue is associated with an impaired survival in critically ill patients

Cell type‐specific actions of thyroid hormones in nonalcoholic steatohepatitis and liver fibrosis

The Medium-Chain Fatty Acid Receptor GPR84 Mediates Myeloid Cell Infiltration Promoting Steatohepatitis and Fibrosis

Dissecting Acute Drug‐Induced Hepatotoxicity and Therapeutic Responses of Steatotic Liver Disease Using Primary Mouse Liver and Blood Cells in a Liver‐On‐A‐Chip Model

Efruxifermin, an investigational treatment for fibrotic or cirrhotic nonalcoholic steatohepatitis (NASH)

Pharmacotherapeutic options for metabolic dysfunction-associated steatotic liver disease: where are we today?

Editorial: prevalence, progression rates and mortality predictors of non‐alcoholic fatty liver disease reflected by German statutory health insurance data

Repair macrophages in acute liver failure

Soluble Urokinase Plasminogen Activator Receptor Levels Are Associated with Severity of Fibrosis in Patients with Primary Sclerosing Cholangitis

Cenicriviroc for the treatment of COVID-19: first interim results of a randomised, placebo-controlled, investigator-initiated, double-blind phase II trial

An integrated view of anti-inflammatory and antifibrotic targets for the treatment of NASH

Association of Serum Calprotectin Concentrations with Mortality in Critically Ill and Septic Patients

Efruxifermin, an investigational treatment for fibrotic or cirrhotic non-alcoholic steatohepatitis (NASH)

Low Serum Levels of Soluble Receptor Activator of Nuclear Factor κ B Ligand (sRANKL) Are Associated with Metabolic Dysregulation and Predict Long-Term Mortality in Critically Ill Patients

THU-291-YI Cellular senescence is a common hallmark in diverse models of steatotic liver diseases

FRI-457 CXCL12 restricts hepatocellular carcinoma progression by shaping the tumor microenvironment in liver fibrosis

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