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Structure of the membrane-assembled retromer coat determined by cryo-electron tomography

Nature (London), 2018-09, Vol.561 (7724), p.561-564

2018

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CALM Regulates Clathrin-Coated Vesicle Size and Maturation by Directly Sensing and Driving Membrane Curvature

Developmental cell, 2015-04, Vol.33 (2), p.163-175

2015

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The Molecular Basis for the Endocytosis of Small R-SNAREs by the Clathrin Adaptor CALM

Cell, 2011-11, Vol.147 (5), p.1118-1131

2011

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Transient Fcho1/2⋅Eps15/R⋅AP-2 Nanoclusters Prime the AP-2 Clathrin Adaptor for Cargo Binding

Developmental cell, 2016-06, Vol.37 (5), p.428-443

2016

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Pulmonary administration of a doxorubicin-conjugated dendrimer enhances drug exposure to lung metastases and improves cancer therapy

Journal of controlled release, 2014-06, Vol.183, p.18-26

2014

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Molecular Basis for Recognition of Dilysine Trafficking Motifs by COPI

Developmental cell, 2012-12, Vol.23 (6), p.1255-1262

2012

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Endocytic sorting of transmembrane protein cargo

Current opinion in cell biology, 2011-08, Vol.23 (4), p.404-412

2011

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A structural explanation for the binding of endocytic dileucine motifs by the AP2 complex

Nature, 2008-12, Vol.456 (7224), p.976-979

2008

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Pulmonary Administration of PEGylated Polylysine Dendrimers: Absorption from the Lung versus Retention within the Lung Is Highly Size-Dependent

Molecular pharmaceutics, 2013-08, Vol.10 (8), p.2986-2995

2013

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A comparison of changes to doxorubicin pharmacokinetics, antitumor activity, and toxicity mediated by PEGylated dendrimer and PEGylated liposome drug delivery systems

Nanomedicine, 2012, Vol.8 (1), p.103-111

2012

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VARP Is Recruited on to Endosomes by Direct Interaction with Retromer, Where Together They Function in Export to the Cell Surface

Developmental cell, 2014-06, Vol.29 (5), p.591-606

2014

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BLOC-1 and BLOC-3 regulate VAMP7 cycling to and from melanosomes via distinct tubular transport carriers

The Journal of cell biology, 2016-08, Vol.214 (3), p.293-308

2016

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Structural basis of Vps33A recruitment to the human HOPS complex by Vps16

Proceedings of the National Academy of Sciences - PNAS, 2013-08, Vol.110 (33), p.13345-13350

2013

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PEGylated polylysine dendrimers increase lymphatic exposure to doxorubicin when compared to PEGylated liposomal and solution formulations of doxorubicin

Journal of controlled release, 2013-11, Vol.172 (1), p.128-136

2013

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Mechanism and evolution of the Zn-fingernail required for interaction of VARP with VPS29

Nature communications, 2020-10, Vol.11 (1), p.5031-5031, Article 5031

2020

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Adaptors for clathrin coats: structure and function

Annual review of cell and developmental biology, 2004-01, Vol.20 (1), p.153-191

2004

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Contribution of the clathrin adaptor AP-1 subunit µ1 to acidic cluster protein sorting

The Journal of cell biology, 2017-09, Vol.216 (9), p.2927-2943

2017

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Syntaxin binding mechanism and disease-causing mutations in Munc18-2

Proceedings of the National Academy of Sciences - PNAS, 2013-11, Vol.110 (47), p.E4482-E4491

2013

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Phagocytosis in the Brain: Homeostasis and Disease

Frontiers in immunology, 2019-04, Vol.10, p.790-790

2019

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Structural Basis of the Intracellular Sorting of the SNARE VAMP7 by the AP3 Adaptor Complex

Developmental cell, 2012-05, Vol.22 (5), p.979-988

2012

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Structural basis for the binding of tryptophan-based motifs by δ-COP

Proceedings of the National Academy of Sciences - PNAS, 2015-11, Vol.112 (46), p.14242-14247

2015

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Phosphatidylinositol-(4,5)-Bisphosphate Regulates Sorting Signal Recognition by the Clathrin-Associated Adaptor Complex AP2

Molecular cell, 2005-05, Vol.18 (5), p.519-531

2005

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The binding of Varp to VAMP7 traps VAMP7 in a closed, fusogenically inactive conformation

Nature structural & molecular biology, 2012-12, Vol.19 (12), p.1300-1309

2012

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Assembly and Solution Structure of the Core Retromer Protein Complex

Traffic (Copenhagen, Denmark), 2011-01, Vol.12 (1), p.56-71

2011

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Doxorubicin-Conjugated PEGylated Dendrimers Show Similar Tumoricidal Activity but Lower Systemic Toxicity When Compared to PEGylated Liposome and Solution Formulations in Mouse and Rat Tumor Models

Molecular pharmaceutics, 2012-03, Vol.9 (3), p.422-432

2012

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Structure of the membrane-assembled retromer coat determined by cryo-electron tomography

CALM Regulates Clathrin-Coated Vesicle Size and Maturation by Directly Sensing and Driving Membrane Curvature

The Molecular Basis for the Endocytosis of Small R-SNAREs by the Clathrin Adaptor CALM

Transient Fcho1/2⋅Eps15/R⋅AP-2 Nanoclusters Prime the AP-2 Clathrin Adaptor for Cargo Binding

Pulmonary administration of a doxorubicin-conjugated dendrimer enhances drug exposure to lung metastases and improves cancer therapy

Molecular Basis for Recognition of Dilysine Trafficking Motifs by COPI

Endocytic sorting of transmembrane protein cargo

A structural explanation for the binding of endocytic dileucine motifs by the AP2 complex

Pulmonary Administration of PEGylated Polylysine Dendrimers: Absorption from the Lung versus Retention within the Lung Is Highly Size-Dependent

A comparison of changes to doxorubicin pharmacokinetics, antitumor activity, and toxicity mediated by PEGylated dendrimer and PEGylated liposome drug delivery systems

VARP Is Recruited on to Endosomes by Direct Interaction with Retromer, Where Together They Function in Export to the Cell Surface

BLOC-1 and BLOC-3 regulate VAMP7 cycling to and from melanosomes via distinct tubular transport carriers

Structural basis of Vps33A recruitment to the human HOPS complex by Vps16

PEGylated polylysine dendrimers increase lymphatic exposure to doxorubicin when compared to PEGylated liposomal and solution formulations of doxorubicin

Mechanism and evolution of the Zn-fingernail required for interaction of VARP with VPS29

Adaptors for clathrin coats: structure and function

Contribution of the clathrin adaptor AP-1 subunit µ1 to acidic cluster protein sorting

Syntaxin binding mechanism and disease-causing mutations in Munc18-2

Phagocytosis in the Brain: Homeostasis and Disease

Structural Basis of the Intracellular Sorting of the SNARE VAMP7 by the AP3 Adaptor Complex

Structural basis for the binding of tryptophan-based motifs by δ-COP

Phosphatidylinositol-(4,5)-Bisphosphate Regulates Sorting Signal Recognition by the Clathrin-Associated Adaptor Complex AP2

The binding of Varp to VAMP7 traps VAMP7 in a closed, fusogenically inactive conformation

Assembly and Solution Structure of the Core Retromer Protein Complex

Doxorubicin-Conjugated PEGylated Dendrimers Show Similar Tumoricidal Activity but Lower Systemic Toxicity When Compared to PEGylated Liposome and Solution Formulations in Mouse and Rat Tumor Models

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