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Serotonin 5‑HT6 Receptor Antagonists for the Treatment of Cognitive Deficiency in Alzheimer’s Disease

Journal of medicinal chemistry, 2014-09, Vol.57 (17), p.7160-7181

2014

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The Antibacterial Cell Division Inhibitor PC190723 Is an FtsZ Polymer-stabilizing Agent That Induces Filament Assembly and Condensation

The Journal of biological chemistry, 2010-05, Vol.285 (19), p.14239-14246

2010

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Optimization of the Pharmacophore Model for 5-HT7R Antagonism. Design and Synthesis of New Naphtholactam and Naphthosultam Derivatives

Journal of medicinal chemistry, 2003-12, Vol.46 (26), p.5638-5650

2003

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The Extracellular Entrance Provides Selectivity to Serotonin 5‑HT7 Receptor Antagonists with Antidepressant-like Behavior in Vivo

Journal of medicinal chemistry, 2014-08, Vol.57 (15), p.6879-6884

2014

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Design, Synthesis and Biological Evaluation of Novel Arachidonic Acid Derivatives as Highly Potent and Selective Endocannabinoid Transporter Inhibitors

Journal of medicinal chemistry, 2001-12, Vol.44 (26), p.4505-4508

2001

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Dual Inhibition of α/β-Hydrolase Domain 6 and Fatty Acid Amide Hydrolase Increases Endocannabinoid Levels in Neurons

The Journal of biological chemistry, 2011-08, Vol.286 (33), p.28723-28728

2011

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New Serotonin 5-HT1A Receptor Agonists with Neuroprotective Effect against Ischemic Cell Damage

Journal of medicinal chemistry, 2011-12, Vol.54 (23), p.7986-7999

2011

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Neurochemical effects of the endocannabinoid uptake inhibitor UCM707 in various rat brain regions

Life sciences (1973), 2007-02, Vol.80 (10), p.979-988

2007

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The optimization of the culture medium to design Streptomyces sp. M7 based impedimetric biosensors

Sensors and actuators. B, Chemical, 2014-03, Vol.193, p.230-237

2014

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Evaluation of Impedance Spectroscopy as a Transduction Method for Bacterial Biosensors

Revista IEEE América Latina, 2013-02, Vol.11 (1), p.196-200

2013

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A Reversible and Selective Inhibitor of Monoacylglycerol Lipase Ameliorates Multiple Sclerosis

Angewandte Chemie (International ed.), 2014-12, Vol.53 (50), p.13765-13770

International ed. in English, 2014

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2-Arachidonoylglycerol Reduces Proteoglycans and Enhances Remyelination in a Progressive Model of Demyelination

The Journal of neuroscience, 2017-08, Vol.37 (35), p.8385-8398

2017

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Monoacylglycerol lipase (MAGL) as a promising therapeutic target

Biochemical pharmacology, 2018-11, Vol.157, p.18-32

2018

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Blocking Ras inhibition as an antitumor strategy

Seminars in cancer biology, 2019-02, Vol.54, p.91-100

2019

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2‐AG limits Theiler's virus induced acute neuroinflammation by modulating microglia and promoting MDSCs

Glia, 2018-07, Vol.66 (7), p.1447-1463

2018

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3-D-QSAR/CoMFA and recognition models of benzimidazole derivatives at the 5-HT4 receptor

Bioorganic & medicinal chemistry letters, 2001-11, Vol.11 (21), p.2807-2811

2001

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A Positive Allosteric Modulator of the Serotonin 5‑HT2C Receptor for Obesity

Journal of medicinal chemistry, 2017-12, Vol.60 (23), p.9575-9584

2017

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Reaction of 6-Hydroxytetrahydro-β-carboline-3-carboxylic Acids with Isocyanates and Isothiocyanates

Chemical and Pharmaceutical Bulletin, 1994/10/15, Vol.42(10), pp.2108-2112

1994

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A Potent Isoprenylcysteine Carboxylmethyltransferase (ICMT) Inhibitor Improves Survival in Ras-Driven Acute Myeloid Leukemia

Journal of medicinal chemistry, 2019-07, Vol.62 (13), p.6035-6046

2019

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Novel Antagonist of the Type 2 Lysophosphatidic Acid Receptor (LPA2), UCM-14216, Ameliorates Spinal Cord Injury in Mice

Journal of medicinal chemistry, 2022-08, Vol.65 (16), p.10956-10974

2022

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Discovery of V‑0219: A Small-Molecule Positive Allosteric Modulator of the Glucagon-Like Peptide‑1 Receptor toward Oral Treatment for “Diabesity”

Journal of medicinal chemistry, 2022-04, Vol.65 (7), p.5449-5461

2022

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Chemical Probes for the Recognition of Cannabinoid Receptors in Native Systems

Angewandte Chemie (International ed.), 2012-07, Vol.51 (28), p.6896-6899

International ed. in English, 2012

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2‑(Fluoromethoxy)-4′‑(S‑methanesulfonimidoyl)-1,1′-biphenyl (UCM-1306), an Orally Bioavailable Positive Allosteric Modulator of the Human Dopamine D1 Receptor for Parkinson’s Disease

Journal of medicinal chemistry, 2022-09, Vol.65 (18), p.12256-12272

2022

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Targeting the FtsZ Allosteric Binding Site with a Novel Fluorescence Polarization Screen, Cytological and Structural Approaches for Antibacterial Discovery

Journal of medicinal chemistry, 2021-05, Vol.64 (9), p.5730-5745

2021

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Development of a Nucleotide Exchange Inhibitor That Impairs Ras Oncogenic Signaling

Chemistry : a European journal, 2017-01, Vol.23 (7), p.1676-1685

2017

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Serotonin 5‑HT6 Receptor Antagonists for the Treatment of Cognitive Deficiency in Alzheimer’s Disease

The Antibacterial Cell Division Inhibitor PC190723 Is an FtsZ Polymer-stabilizing Agent That Induces Filament Assembly and Condensation

Optimization of the Pharmacophore Model for 5-HT7R Antagonism. Design and Synthesis of New Naphtholactam and Naphthosultam Derivatives

The Extracellular Entrance Provides Selectivity to Serotonin 5‑HT7 Receptor Antagonists with Antidepressant-like Behavior in Vivo

Design, Synthesis and Biological Evaluation of Novel Arachidonic Acid Derivatives as Highly Potent and Selective Endocannabinoid Transporter Inhibitors

Dual Inhibition of α/β-Hydrolase Domain 6 and Fatty Acid Amide Hydrolase Increases Endocannabinoid Levels in Neurons

New Serotonin 5-HT1A Receptor Agonists with Neuroprotective Effect against Ischemic Cell Damage

Neurochemical effects of the endocannabinoid uptake inhibitor UCM707 in various rat brain regions

The optimization of the culture medium to design Streptomyces sp. M7 based impedimetric biosensors

Evaluation of Impedance Spectroscopy as a Transduction Method for Bacterial Biosensors

A Reversible and Selective Inhibitor of Monoacylglycerol Lipase Ameliorates Multiple Sclerosis

2-Arachidonoylglycerol Reduces Proteoglycans and Enhances Remyelination in a Progressive Model of Demyelination

Monoacylglycerol lipase (MAGL) as a promising therapeutic target

Blocking Ras inhibition as an antitumor strategy

2‐AG limits Theiler's virus induced acute neuroinflammation by modulating microglia and promoting MDSCs

3-D-QSAR/CoMFA and recognition models of benzimidazole derivatives at the 5-HT4 receptor

A Positive Allosteric Modulator of the Serotonin 5‑HT2C Receptor for Obesity

Reaction of 6-Hydroxytetrahydro-β-carboline-3-carboxylic Acids with Isocyanates and Isothiocyanates

A Potent Isoprenylcysteine Carboxylmethyltransferase (ICMT) Inhibitor Improves Survival in Ras-Driven Acute Myeloid Leukemia

Novel Antagonist of the Type 2 Lysophosphatidic Acid Receptor (LPA2), UCM-14216, Ameliorates Spinal Cord Injury in Mice

Discovery of V‑0219: A Small-Molecule Positive Allosteric Modulator of the Glucagon-Like Peptide‑1 Receptor toward Oral Treatment for “Diabesity”

Chemical Probes for the Recognition of Cannabinoid Receptors in Native Systems

2‑(Fluoromethoxy)-4′‑(S‑methanesulfonimidoyl)-1,1′-biphenyl (UCM-1306), an Orally Bioavailable Positive Allosteric Modulator of the Human Dopamine D1 Receptor for Parkinson’s Disease

Targeting the FtsZ Allosteric Binding Site with a Novel Fluorescence Polarization Screen, Cytological and Structural Approaches for Antibacterial Discovery

Development of a Nucleotide Exchange Inhibitor That Impairs Ras Oncogenic Signaling

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