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The role of HER2, EGFR, and other receptor tyrosine kinases in breast cancer

Cancer and metastasis reviews, 2016-12, Vol.35 (4), p.575-588

2016

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Mechanisms regulating PD-L1 expression in cancers and associated opportunities for novel small-molecule therapeutics

Nature reviews. Clinical oncology, 2022-05, Vol.19 (5), p.287-305

2022

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Protein localization in disease and therapy

Journal of cell science, 2011-10, Vol.124 (Pt 20), p.3381-3392

2011

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Mechanisms Controlling PD-L1 Expression in Cancer

Molecular cell, 2019-11, Vol.76 (3), p.359-370

2019

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Galectin-9 interacts with PD-1 and TIM-3 to regulate T cell death and is a target for cancer immunotherapy

Nature communications, 2021-02, Vol.12 (1), p.832-17, Article 832

2021

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BAP1 links metabolic regulation of ferroptosis to tumour suppression

Nature cell biology, 2018-10, Vol.20 (10), p.1181-1192

2018

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PARP Inhibitor Upregulates PD-L1 Expression and Enhances Cancer-Associated Immunosuppression

Clinical cancer research, 2017-07, Vol.23 (14), p.3711-3720

2017

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PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis

Nature cell biology, 2020-10, Vol.22 (10), p.1264-1275

2020

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Exosomal PD-L1 harbors active defense function to suppress T cell killing of breast cancer cells and promote tumor growth

Cell research, 2018-08, Vol.28 (8), p.862-864

2018

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Regulation and Role of EZH2 in Cancer

Cancer Research and Treatment, 2014, 46(3), , pp.209-222

2014

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Disruption of tumour-associated macrophage trafficking by the osteopontin-induced colony-stimulating factor-1 signalling sensitises hepatocellular carcinoma to anti-PD-L1 blockade

Gut, 2019-09, Vol.68 (9), p.1653-1666

2019

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Proteolytic cleavage, trafficking, and functions of nuclear receptor tyrosine kinases

The FEBS journal, 2015-10, Vol.282 (19), p.3693-3721

2015

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Palmitoylation stabilizes PD-L1 to promote breast tumor growth

Cell research, 2019-01, Vol.29 (1), p.83-86

2019

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TYRO3 induces anti-PD-1/PD-L1 therapy resistance by limiting innate immunity and tumoral ferroptosis

The Journal of clinical investigation, 2021-04, Vol.131 (8), p.1-13

2021

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Activated T cell-derived exosomal PD-1 attenuates PD-L1-induced immune dysfunction in triple-negative breast cancer

Oncogene, 2021-08, Vol.40 (31), p.4992-5001

2021

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The Adaptor Protein CARD9 Protects against Colon Cancer by Restricting Mycobiota-Mediated Expansion of Myeloid-Derived Suppressor Cells

Immunity (Cambridge, Mass.), 2018-09, Vol.49 (3), p.504-514.e4

2018

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Removal of N-Linked Glycosylation Enhances PD-L1 Detection and Predicts Anti-PD-1/PD-L1 Therapeutic Efficacy

Cancer cell, 2019-08, Vol.36 (2), p.168-178.e4

2019

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Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1

Molecular cell, 2018-08, Vol.71 (4), p.606-620.e7

2018

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Glucocorticoid receptor regulates PD-L1 and MHC-I in pancreatic cancer cells to promote immune evasion and immunotherapy resistance

Nature communications, 2021-12, Vol.12 (1), p.7041-7041, Article 7041

2021

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Deubiquitination and Stabilization of PD-L1 by CSN5

Cancer cell, 2016-12, Vol.30 (6), p.925-939

2016

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lncRNA Directs Cooperative Epigenetic Regulation Downstream of Chemokine Signals

Cell, 2014-11, Vol.159 (5), p.1110-1125

2014

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Actin cytoskeleton remodeling drives epithelial‐mesenchymal transition for hepatoma invasion and metastasis in mice

Hepatology (Baltimore, Md.), 2018-06, Vol.67 (6), p.2226-2243

2018

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IL-6/JAK1 pathway drives PD-L1 Y112 phosphorylation to promote cancer immune evasion

The Journal of clinical investigation, 2019-08, Vol.129 (8), p.3324-3338

2019

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Eradication of Triple-Negative Breast Cancer Cells by Targeting Glycosylated PD-L1

Cancer cell, 2018-02, Vol.33 (2), p.187-201.e10

2018

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Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity

Nature communications, 2016-08, Vol.7 (1), p.12632-11, Article 12632

2016

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The role of HER2, EGFR, and other receptor tyrosine kinases in breast cancer

Mechanisms regulating PD-L1 expression in cancers and associated opportunities for novel small-molecule therapeutics

Protein localization in disease and therapy

Mechanisms Controlling PD-L1 Expression in Cancer

Galectin-9 interacts with PD-1 and TIM-3 to regulate T cell death and is a target for cancer immunotherapy

BAP1 links metabolic regulation of ferroptosis to tumour suppression

PARP Inhibitor Upregulates PD-L1 Expression and Enhances Cancer-Associated Immunosuppression

PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis

Exosomal PD-L1 harbors active defense function to suppress T cell killing of breast cancer cells and promote tumor growth

Regulation and Role of EZH2 in Cancer

Disruption of tumour-associated macrophage trafficking by the osteopontin-induced colony-stimulating factor-1 signalling sensitises hepatocellular carcinoma to anti-PD-L1 blockade

Proteolytic cleavage, trafficking, and functions of nuclear receptor tyrosine kinases

Palmitoylation stabilizes PD-L1 to promote breast tumor growth

TYRO3 induces anti-PD-1/PD-L1 therapy resistance by limiting innate immunity and tumoral ferroptosis

Activated T cell-derived exosomal PD-1 attenuates PD-L1-induced immune dysfunction in triple-negative breast cancer

The Adaptor Protein CARD9 Protects against Colon Cancer by Restricting Mycobiota-Mediated Expansion of Myeloid-Derived Suppressor Cells

Removal of N-Linked Glycosylation Enhances PD-L1 Detection and Predicts Anti-PD-1/PD-L1 Therapeutic Efficacy

Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1

Glucocorticoid receptor regulates PD-L1 and MHC-I in pancreatic cancer cells to promote immune evasion and immunotherapy resistance

Deubiquitination and Stabilization of PD-L1 by CSN5

lncRNA Directs Cooperative Epigenetic Regulation Downstream of Chemokine Signals

Actin cytoskeleton remodeling drives epithelial‐mesenchymal transition for hepatoma invasion and metastasis in mice

IL-6/JAK1 pathway drives PD-L1 Y112 phosphorylation to promote cancer immune evasion

Eradication of Triple-Negative Breast Cancer Cells by Targeting Glycosylated PD-L1

Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity

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