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Synthesis and biological evaluation of novel unsaturated carboxysteroids as human 5α-reductase inhibitors: A legitimate approach

European journal of medicinal chemistry, 2012-08, Vol.54, p.728-739

2012

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In vitro reconstitution of α-pyrone ring formation in myxopyronin biosynthesis

Chemical science (Cambridge), 2015-08, Vol.6 (8), p.5076-5085

2015

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A New Class of Nonsteroidal Aromatase Inhibitors: Design and Synthesis of Chromone and Xanthone Derivatives and Inhibition of the P450 Enzymes Aromatase and 17α-Hydroxylase/C17,20-Lyase

Journal of medicinal chemistry, 2001-03, Vol.44 (5), p.672-680

2001

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Steering the azido-tetrazole equilibrium of 4-azidopyrimidines via substituent variation - implications for drug design and azide-alkyne cycloadditions

Organic & biomolecular chemistry, 2015-01, Vol.13 (43), p.10620-10630

2015

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Computational prediction of new CYP17 inhibitors based on pharmacophore modeling, virtual screening and docking approach

Pharmazie, 2017-09, Vol.72 (9), p.529-536

2017

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Synthesis and Evaluation of Novel Steroidal Oxime Inhibitors of P450 17 (17α-Hydroxylase/C17−20-Lyase) and 5α-Reductase Types 1 and 2

Journal of medicinal chemistry, 2000-11, Vol.43 (22), p.4266-4277

2000

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Airing Your Dirty Laundry: Vertical Integration, Reputational Capital, and Social Networks

Journal of law, economics, & organization, 2011-08, Vol.27 (2), p.219-244, Article 219

2011

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Design, Synthesis, and 3D QSAR of Novel Potent and Selective Aromatase Inhibitors

Journal of medicinal chemistry, 2004-12, Vol.47 (27), p.6792-6803

2004

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Imidazole substituted biphenyls : A new class of highly potent and in vivo active inhibitors of P450 17 as potential therapeutics for treatment of prostate cancer

Bioorganic & medicinal chemistry, 1999-09, Vol.7 (9), p.1913-1924

1999

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Inhibition of 5 alpha-reductase and aromatase by the ellagitannins oenothein A and oenothein B from Epilobium species

Planta medica, 1997-04, Vol.63 (2), p.111-114

1997

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New selective nonsteroidal aromatase inhibitors : Synthesis and inhibitory activity of 2, 3 or 5-(α-azolylbenzyl)-1H-indoles

Bioorganic & medicinal chemistry letters, 1999-02, Vol.9 (3), p.333-336

1999

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Effects of novel 17α-hydroxylase/C17, 20-lyase (P450 17, CYP 17) inhibitors on androgen biosynthesis in vitro and in vivo

The Journal of steroid biochemistry and molecular biology, 2003-04, Vol.84 (5), p.555-562

2003

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Etomidate unmasks intraadrenal regulation of steroidogenesis and proliferation in adrenal cortical cell lines

Hormone and metabolic research, 2010-06, Vol.42 (7), p.528-534

2010

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Aromatase Inhibitors. Syntheses and Structure-Activity Studies of Novel Pyridyl-Substituted Indanones, Indans, and Tetralins

Journal of medicinal chemistry, 1994-04, Vol.37 (9), p.1275-1281

1994

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Ludwig's angina in children

American family physician, 1999-07, Vol.60 (1), p.109-112

Hartmann, Jr, R W

1999

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Comparison of Envelope 2 CD81 binding regions in PBMC-derived versus serum-derived hepatitis C virus isolates: higher conservation of CD81 region 2 in PBMC isolates

Journal of viral hepatitis, 2011-03, Vol.18 (3), p.181-192

2011

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Identification of monohydroxy progesterones produced by CYP106A2 using comparative HPLC and electrospray ionisation collision-induced dissociation mass spectrometry

Biochemical and biophysical research communications, 2004-06, Vol.319 (2), p.677-682

2004

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The Wittig bioconjugation of maleimide derived, water soluble phosphonium ylides to aldehyde-tagged proteins

Organic & biomolecular chemistry, 2021-12, Vol.19 (47), p.1417-1423

2021

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Pyridyl-Substituted Tetrahydrocyclopropa[a]naphthalenes: Highly Active and Selective Inhibitors of P450 arom

Journal of medicinal chemistry, 1995-06, Vol.38 (12), p.2103-2111

1995

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Synthesis of Hydroxy Derivatives of Highly Potent Non-steroidal CYP 17 Inhibitors as Potential Metabolites and Evaluation of their Activity by a Non Cellular Assay using Recombinant Human Enzyme

Journal of enzyme inhibition and medicinal chemistry, 2004-02, Vol.19 (1), p.17-32

2004

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1-imidazolyl(alkyl)-substituted di- and tetrahydroquinolines and analogues: syntheses and evaluation of dual inhibitors of thromboxane A(2) synthase and aromatase

Journal of medicinal chemistry, 2000-05, Vol.43 (9), p.1841-1851

2000

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Pyridyl Substituted Benzocycloalkenes: New Inhibitors of 17α-Hydroxylase/ 17,20-Lyase (P450 17α)

Journal of enzyme inhibition, 1994, Vol.8 (2), p.113-122

1994

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Aromatase inhibitors. Synthesis and evaluation of mammary tumor inhibiting activity of 3-alkylated 3-(4-aminophenyl)piperidine-2,6-diones

Journal of medicinal chemistry, 1986-08, Vol.29 (8), p.1362-1369

1986

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Synthesis and In Vitro Evaluation of 3-(1-Azolylmethyl)-1H-indoles and 3-(1-Azolyl-1-phenylmethyl)-1H-indoles as Inhibitors of P450 arom

Archiv der Pharmazie (Weinheim), 1997-05, Vol.330 (5), p.141-145

1997

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New aromatase inhibitors. Synthesis and biological activity of pyridyl-substituted tetralone derivatives

Journal of medicinal chemistry, 1991-09, Vol.34 (9), p.2685-2691

1991

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Synthesis and biological evaluation of novel unsaturated carboxysteroids as human 5α-reductase inhibitors: A legitimate approach

In vitro reconstitution of α-pyrone ring formation in myxopyronin biosynthesis

A New Class of Nonsteroidal Aromatase Inhibitors: Design and Synthesis of Chromone and Xanthone Derivatives and Inhibition of the P450 Enzymes Aromatase and 17α-Hydroxylase/C17,20-Lyase

Steering the azido-tetrazole equilibrium of 4-azidopyrimidines via substituent variation - implications for drug design and azide-alkyne cycloadditions

Computational prediction of new CYP17 inhibitors based on pharmacophore modeling, virtual screening and docking approach

Synthesis and Evaluation of Novel Steroidal Oxime Inhibitors of P450 17 (17α-Hydroxylase/C17−20-Lyase) and 5α-Reductase Types 1 and 2

Airing Your Dirty Laundry: Vertical Integration, Reputational Capital, and Social Networks

Design, Synthesis, and 3D QSAR of Novel Potent and Selective Aromatase Inhibitors

Imidazole substituted biphenyls : A new class of highly potent and in vivo active inhibitors of P450 17 as potential therapeutics for treatment of prostate cancer

Inhibition of 5 alpha-reductase and aromatase by the ellagitannins oenothein A and oenothein B from Epilobium species

New selective nonsteroidal aromatase inhibitors : Synthesis and inhibitory activity of 2, 3 or 5-(α-azolylbenzyl)-1H-indoles

Effects of novel 17α-hydroxylase/C17, 20-lyase (P450 17, CYP 17) inhibitors on androgen biosynthesis in vitro and in vivo

Etomidate unmasks intraadrenal regulation of steroidogenesis and proliferation in adrenal cortical cell lines

Aromatase Inhibitors. Syntheses and Structure-Activity Studies of Novel Pyridyl-Substituted Indanones, Indans, and Tetralins

Ludwig's angina in children

Comparison of Envelope 2 CD81 binding regions in PBMC-derived versus serum-derived hepatitis C virus isolates: higher conservation of CD81 region 2 in PBMC isolates

Identification of monohydroxy progesterones produced by CYP106A2 using comparative HPLC and electrospray ionisation collision-induced dissociation mass spectrometry

The Wittig bioconjugation of maleimide derived, water soluble phosphonium ylides to aldehyde-tagged proteins

Pyridyl-Substituted Tetrahydrocyclopropa[a]naphthalenes: Highly Active and Selective Inhibitors of P450 arom

Synthesis of Hydroxy Derivatives of Highly Potent Non-steroidal CYP 17 Inhibitors as Potential Metabolites and Evaluation of their Activity by a Non Cellular Assay using Recombinant Human Enzyme

1-imidazolyl(alkyl)-substituted di- and tetrahydroquinolines and analogues: syntheses and evaluation of dual inhibitors of thromboxane A(2) synthase and aromatase

Pyridyl Substituted Benzocycloalkenes: New Inhibitors of 17α-Hydroxylase/ 17,20-Lyase (P450 17α)

Aromatase inhibitors. Synthesis and evaluation of mammary tumor inhibiting activity of 3-alkylated 3-(4-aminophenyl)piperidine-2,6-diones

Synthesis and In Vitro Evaluation of 3-(1-Azolylmethyl)-1H-indoles and 3-(1-Azolyl-1-phenylmethyl)-1H-indoles as Inhibitors of P450 arom

New aromatase inhibitors. Synthesis and biological activity of pyridyl-substituted tetralone derivatives

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