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Tamiflu: The Supply Problem

Angewandte Chemie International Edition, 2006-11, Vol.45 (44), p.7330-7334

2006

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Research and Development of a Second-Generation Process for Oseltamivir Phosphate, Prodrug for a Neuraminidase Inhibitor

Organic process research & development, 2004-01, Vol.8 (1), p.86-91

2004

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Facile and Scalable Methodology for the Pyrrolo[2,1‑f][1,2,4]triazine of Remdesivir

Organic process research & development, 2022-01, Vol.26 (1), p.82-90

2022

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A highly stereocontrolled, four-step synthesis of (.+-.)-lasubine II

Journal of the American Chemical Society, 1988-10, Vol.110 (22), p.7445-7447

1988

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Ortho metalation directed by .alpha.-amino alkoxides

Journal of organic chemistry, 1984-03, Vol.49 (6), p.1078-1083

1984

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Development of a Safer Continuous Flow Process for B2(OH)4‑Mediated Chemoselective Reduction of Nitroarenes to Anilines

Organic process research & development, 2024-10, Vol.28 (10), p.3847-3857

2024

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Development of a Safer Continuous Flow Process for B 2 (OH) 4 -Mediated Chemoselective Reduction of Nitroarenes to Anilines

Organic process research & development, 2024-10, Vol.28 (10), p.3847-3857

2024

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Additiom of Grignard reagents to 1-acyl-4-methoxypyridinum salts. An approach to the synthesis of quinolizidinones

Tetrahedron letters, 1986, Vol.27 (38), p.4549-4552

1986

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The first nonenzymic stereospecific intramolecular reduction by an NADH-mimic containing a covalently bound carbonyl moiety

Journal of the American Chemical Society, 1987-05, Vol.109 (10), p.3155-3156

1987

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Directed lithiation of tertiary .beta.-amino benzamides

Journal of organic chemistry, 1986-09, Vol.51 (19), p.3566-3572

1986

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Asymmetric synthesis of naproxen via a pinacol-type reaction

Tetrahedron: asymmetry, 1992-12, Vol.3 (12), p.1551-1552

Brown, Jack D.

1992

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Ortho substitution of m-anisaldehyde via .alpha.-amino alkoxide directed lithiation

Journal of organic chemistry, 1989-07, Vol.54 (15), p.3730-3732

1989

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Tamiflu: Das Versorgungsproblem

Angewandte Chemie, 2006-11, Vol.118 (44), p.7488-7492

2006

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Regioselective addition of titanium enolates to 1-acylpyridinium salts. A convenient synthesis of 4-(2-oxoalkyl)pyridines

Tetrahedron letters, 1984, Vol.25 (31), p.3297-3300

1984

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Stereospecific conjugate addition of organolithium reagents to naphthylimines. A facile route to 1,1,2- and 1,2-substituted dihydroronaphthalenes

Tetrahedron letters, 1987, Vol.28 (44), p.5279-5282

1987

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Tamiflu: The Supply Problem

ChemInform, 2007-02, Vol.38 (6), p.no-no

2007

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The in situ protection of aldehydes via α-amino alkoxides

Tetrahedron letters, 1981, Vol.22 (42), p.4213-4216

1981

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A one-pot alkylation of aromatic aldehydes

Tetrahedron letters, 1982, Vol.23 (39), p.3979-3982

1982

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Stereoselective reduction of C=X by a chiral 1,4-dihydropyridine (NADH-MIMIC) in a self-immolative process

Tetrahedron letters, 1988, Vol.29 (44), p.5617-5620

1988

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Additon of metallo enolates to 1-acylpyridinium salts. A short synthesis of (±)-[formula omitted]-lupinine

Tetrahedron letters, 1986, Vol.27 (20), p.2219-2222

1986

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Asymmetric synthesis of 1,1,2- and 1,2-substituted dihydronaphthalenes via a chiral naphthyl imine

Tetrahedron letters, 1987, Vol.28 (44), p.5283-5286

1987

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New synthetic methods: A. The chemistry of alpha-amino alkoxides. B. 1-acyldihydropyridines as intermediates for natural product synthesis

Brown, Jack D

1987

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Ortho metalation directed by α-amino alkoxides. An improved synthesis of ortho-substituted aryl ketones

Tetrahedron letters, 1983, Vol.24 (49), p.5465-5468

1983

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Tamiflu: The Supply Problem

Research and Development of a Second-Generation Process for Oseltamivir Phosphate, Prodrug for a Neuraminidase Inhibitor

Facile and Scalable Methodology for the Pyrrolo[2,1‑f][1,2,4]triazine of Remdesivir

Development of a Scalable, Chromatography-Free Synthesis of t‑Bu-SMS-Phos and Application to the Synthesis of an Important Chiral CF3‑Alcohol Derivative with High Enantioselectivity Using Rh-Catalyzed Asymmetric Hydrogenation

Development of a Scalable, Chromatography-Free Synthesis of t-Bu-SMS-Phos and Application to the Synthesis of an Important Chiral CF 3 -Alcohol Derivative with High Enantioselectivity Using Rh-Catalyzed Asymmetric Hydrogenation

A highly stereocontrolled, four-step synthesis of (.+-.)-lasubine II

Ortho metalation directed by .alpha.-amino alkoxides

Development of a Safer Continuous Flow Process for B2(OH)4‑Mediated Chemoselective Reduction of Nitroarenes to Anilines

Development of a Safer Continuous Flow Process for B 2 (OH) 4 -Mediated Chemoselective Reduction of Nitroarenes to Anilines

Additiom of Grignard reagents to 1-acyl-4-methoxypyridinum salts. An approach to the synthesis of quinolizidinones

The first nonenzymic stereospecific intramolecular reduction by an NADH-mimic containing a covalently bound carbonyl moiety

Directed lithiation of tertiary .beta.-amino benzamides

Asymmetric synthesis of naproxen via a pinacol-type reaction

Ortho substitution of m-anisaldehyde via .alpha.-amino alkoxide directed lithiation

Tamiflu: Das Versorgungsproblem

Regioselective addition of titanium enolates to 1-acylpyridinium salts. A convenient synthesis of 4-(2-oxoalkyl)pyridines

Stereospecific conjugate addition of organolithium reagents to naphthylimines. A facile route to 1,1,2- and 1,2-substituted dihydroronaphthalenes

Tamiflu: The Supply Problem

The in situ protection of aldehydes via α-amino alkoxides

A one-pot alkylation of aromatic aldehydes

Stereoselective reduction of C=X by a chiral 1,4-dihydropyridine (NADH-MIMIC) in a self-immolative process

Additon of metallo enolates to 1-acylpyridinium salts. A short synthesis of (±)-[formula omitted]-lupinine

Asymmetric synthesis of 1,1,2- and 1,2-substituted dihydronaphthalenes via a chiral naphthyl imine

New synthetic methods: A. The chemistry of alpha-amino alkoxides. B. 1-acyldihydropyridines as intermediates for natural product synthesis

Ortho metalation directed by α-amino alkoxides. An improved synthesis of ortho-substituted aryl ketones

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