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E3 Ligase TRAF6 Regulates Akt Ubiquitination and Activation

Science (American Association for the Advancement of Science), 2009-08, Vol.325 (5944), p.1134-1138

2009

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Multiple functions of Osterix are required for bone growth and homeostasis in postnatal mice

Proceedings of the National Academy of Sciences - PNAS, 2010-07, Vol.107 (29), p.12919-12924

2010

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The E3 Ubiquitin Ligase TRAF6 Intercedes in Starvation-Induced Skeletal Muscle Atrophy through Multiple Mechanisms

Molecular and Cellular Biology, 2012-04, Vol.32 (7), p.1248-1259

2012

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Targeted ablation of TRAF6 inhibits skeletal muscle wasting in mice

The Journal of cell biology, 2010-12, Vol.191 (7), p.1395-1411

2010

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TAK1 Is Essential for Osteoclast Differentiation and Is an Important Modulator of Cell Death by Apoptosis and Necroptosis

Molecular and Cellular Biology, 2013-02, Vol.33 (3), p.582-595

2013

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Cthrc1 is a positive regulator of osteoblastic bone formation

PloS one, 2008-09, Vol.3 (9), p.e3174-e3174

2008

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Ubiquitin-specific protease 25 regulates TLR4-dependent innate immune responses through deubiquitination of the adaptor protein TRAF3

Science signaling, 2013-05, Vol.6 (275), p.ra35

2013

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Site-specific Lys-63-linked Tumor Necrosis Factor Receptor-associated Factor 6 Auto-ubiquitination Is a Critical Determinant of IκB Kinase Activation

The Journal of biological chemistry, 2007-02, Vol.282 (6), p.4102-4112

2007

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Association Between Imatinib-Resistant BCR-ABL Mutation-Negative Leukemia and Persistent Activation of LYN Kinase

JNCI : Journal of the National Cancer Institute, 2008-07, Vol.100 (13), p.926-939

2008

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Protein MRI contrast agent with unprecedented metal selectivity and sensitivity for liver cancer imaging

Proceedings of the National Academy of Sciences - PNAS, 2015-05, Vol.112 (21), p.6607-6612

2015

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The RING Domain and First Zinc Finger of TRAF6 Coordinate Signaling by Interleukin-1, Lipopolysaccharide, and RANKL

The Journal of biological chemistry, 2008-09, Vol.283 (36), p.24871-24880

2008

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Hypoxia-induced SUMOylation of E3 ligase HAF determines specific activation of HIF2 in clear-cell renal cell carcinoma

Cancer research (Chicago, Ill.), 2015-01, Vol.75 (2), p.316-329

2015

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TRAF6 and the Three C-Terminal Lysine Sites on IRF7 Are Required for Its Ubiquitination-Mediated Activation by the Tumor Necrosis Factor Receptor Family Member Latent Membrane Protein 1

Molecular and Cellular Biology, 2008-10, Vol.28 (20), p.6536-6546

2008

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Deletion of TAK1 in the myeloid lineage results in the spontaneous development of myelomonocytic leukemia in mice

PloS one, 2012-12, Vol.7 (12), p.e51228

2012

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Critical Role of Monoubiquitination of Histone H2AX Protein in Histone H2AX Phosphorylation and DNA Damage Response

The Journal of biological chemistry, 2011-09, Vol.286 (35), p.30806-30815

2011

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Tumor Necrosis Factor Receptor-associated Factor 6 (TRAF6) and TGFβ-activated Kinase 1 (TAK1) Play Essential Roles in the C-type Lectin Receptor Signaling in Response to Candida albicans Infection

The Journal of biological chemistry, 2012-12, Vol.287 (53), p.44143-44150

2012

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TAK1-dependent Signaling Requires Functional Interaction with TAB2/TAB3

The Journal of biological chemistry, 2007-02, Vol.282 (6), p.3918-3928

2007

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Improved Clearance during Treatment of HPV-Positive Head and Neck Cancer through mTOR Inhibition

Neoplasia (New York, N.Y.), 2013-06, Vol.15 (6), p.620-IN10

2013

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TRAF6 ubiquitin ligase is essential for RANKL signaling and osteoclast differentiation

Biochemical and biophysical research communications, 2007-08, Vol.359 (4), p.1044-1049

2007

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Distinct molecular mechanism for initiating TRAF6 signalling

Nature (London), 2002-07, Vol.418 (6896), p.443-447

2002

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BSTA promotes mTORC2-mediated phosphorylation of Akt1 to suppress expression of FoxC2 and stimulate adipocyte differentiation

Science signaling, 2013-01, Vol.6 (257), p.ra2

2013

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Mitochondrial Akt Regulation of Hypoxic Tumor Reprogramming

Cancer cell, 2016-08, Vol.30 (2), p.257-272

2016

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Prevention of fetal infection in heifers challenged with bovine viral diarrhoea virus type 1a by vaccination with a type 1c or type 1a vaccine

New Zealand veterinary journal, 2017-05, Vol.65 (3), p.134-139

2017

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Genetic Ablation of Caveolin-1 Drives Estrogen-Hypersensitivity and the Development of DCIS-Like Mammary Lesions

The American journal of pathology, 2009-04, Vol.174 (4), p.1172-1190

2009

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Trifunctional inhibition of COX-2 by extracts of Lonicera japonica: Direct inhibition, transcriptional and post-transcriptional down regulation

Journal of ethnopharmacology, 2007-05, Vol.111 (3), p.667-670

2007

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E3 Ligase TRAF6 Regulates Akt Ubiquitination and Activation

Multiple functions of Osterix are required for bone growth and homeostasis in postnatal mice

The E3 Ubiquitin Ligase TRAF6 Intercedes in Starvation-Induced Skeletal Muscle Atrophy through Multiple Mechanisms

Targeted ablation of TRAF6 inhibits skeletal muscle wasting in mice

TAK1 Is Essential for Osteoclast Differentiation and Is an Important Modulator of Cell Death by Apoptosis and Necroptosis

Cthrc1 is a positive regulator of osteoblastic bone formation

Ubiquitin-specific protease 25 regulates TLR4-dependent innate immune responses through deubiquitination of the adaptor protein TRAF3

Site-specific Lys-63-linked Tumor Necrosis Factor Receptor-associated Factor 6 Auto-ubiquitination Is a Critical Determinant of IκB Kinase Activation

Association Between Imatinib-Resistant BCR-ABL Mutation-Negative Leukemia and Persistent Activation of LYN Kinase

Protein MRI contrast agent with unprecedented metal selectivity and sensitivity for liver cancer imaging

The RING Domain and First Zinc Finger of TRAF6 Coordinate Signaling by Interleukin-1, Lipopolysaccharide, and RANKL

Hypoxia-induced SUMOylation of E3 ligase HAF determines specific activation of HIF2 in clear-cell renal cell carcinoma

TRAF6 and the Three C-Terminal Lysine Sites on IRF7 Are Required for Its Ubiquitination-Mediated Activation by the Tumor Necrosis Factor Receptor Family Member Latent Membrane Protein 1

Deletion of TAK1 in the myeloid lineage results in the spontaneous development of myelomonocytic leukemia in mice

Critical Role of Monoubiquitination of Histone H2AX Protein in Histone H2AX Phosphorylation and DNA Damage Response

Tumor Necrosis Factor Receptor-associated Factor 6 (TRAF6) and TGFβ-activated Kinase 1 (TAK1) Play Essential Roles in the C-type Lectin Receptor Signaling in Response to Candida albicans Infection

TAK1-dependent Signaling Requires Functional Interaction with TAB2/TAB3

Improved Clearance during Treatment of HPV-Positive Head and Neck Cancer through mTOR Inhibition

TRAF6 ubiquitin ligase is essential for RANKL signaling and osteoclast differentiation

Distinct molecular mechanism for initiating TRAF6 signalling

BSTA promotes mTORC2-mediated phosphorylation of Akt1 to suppress expression of FoxC2 and stimulate adipocyte differentiation

Mitochondrial Akt Regulation of Hypoxic Tumor Reprogramming

Prevention of fetal infection in heifers challenged with bovine viral diarrhoea virus type 1a by vaccination with a type 1c or type 1a vaccine

Genetic Ablation of Caveolin-1 Drives Estrogen-Hypersensitivity and the Development of DCIS-Like Mammary Lesions

Trifunctional inhibition of COX-2 by extracts of Lonicera japonica: Direct inhibition, transcriptional and post-transcriptional down regulation

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