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0.45% saline and 5% dextrose in water, but not 0.9% saline or 5% dextrose in 0.9% saline, worsen brain edema two hours after closed head trauma in rats two hours after closed head trauma in rats

Anesthesia and analgesia, 1998, Vol.86 (6), p.1225-1229

1998

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1-{1-[4-[(N-acetyl-4-piperidinyl)oxy]-2-methoxybenzoyl]piperidin-4-yl}-4H-3,1-benzoxazin-2(1H)-one (L-371,257) : a new, orally bioavailable, non-peptide oxytocin antagonist

Journal of medicinal chemistry, 1995-11, Vol.38 (23), p.4634-4636

1995

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1-2-(2,2,2-Trifluoroethoxy)ethyl-1H-pyrazolo[4,3-d]pyrimidines as potent phosphodiesterase 5 (PDE5) inhibitors

Bioorganic & medicinal chemistry letters, 2010, Vol.20 (10), p.3125-3128

2010

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1,2,3-Triazolo[5,4-e]1,2,4-triazolo[1,5-c]pyrimidine derivatives: a new class of A2A adenosine receptor antagonists

Farmaco (Società chimica italiana : 1989), 1996-04, Vol.51 (4), p.297

1996

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1-[2-[(5-Cyanopyridin-2-yl)amino]-ethylamino]acetyl-2-(S)-pyrrolidine-carbonitri le: A potent, selective, and orally bioavailable Dipeptidyl peptidase IV inhibitor with antihyperglycemic properties

Journal of medicinal chemistry, 2002, Vol.45 (12), p.2362-2365

2002

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1,2,5-Thiadiazole Analogues of Aceclidine as Potent m1 Muscarinic Agonists

Journal of medicinal chemistry, 1998-01, Vol.41 (3), p.379-392

1998

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1,2-Diarylcyclopentenes as Selective Cyclooxygenase-2 Inhibitors and Orally Active Anti-inflammatory Agents

Journal of medicinal chemistry, 1995-10, Vol.38 (22), p.4570-4578

1995

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1,25-Dihydroxycalciferol and calcium therapy in osteoporosis with calcium malabsorption. Dose response relationship of calcium absorption and indices of bone turnover

Mineral and electrolyte metabolism, 1985, Vol.11 (1), p.35

1985

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1,25-dihydroxyvitamin D3 inhibits transcription of type I collagen genes in the rat osteosarcoma cell line ROS 17/2.8

Endocrinology (Philadelphia), 1989-07, Vol.125 (1), p.327-333

1989

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1,25-dihydroxyvitamin D3 synthetic analogs inhibit spontaneous metastases in a 1,2-dimethylhydrazine-induced colon carcinogenesis model

International journal of oncology, 2000-06, Vol.16 (6), p.1249

2000

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1-(3-Cyanobenzylpiperidin-4-yl)-5-methyl-4-phenyl-1,3-dihydroimidazol-2-one : A selective high-affinity antagonist for the human dopamine D4receptor with excellent selectivity over ion channels

Journal of medicinal chemistry, 1999, Vol.42 (14), p.2706-2715

1999

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1,3-dialkyltriazenes : reactie intermediates and DNA alkylation

Chemical research in toxicology, 1991, Vol.4 (3), p.334-340

1991

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1,3-dioxane-4,6-dione-5-carboxamide-based inhibitors of human group IIa phospholipase A2 : X-ray structure of the complex and interfacial selection of inhibitors from a structural library

Bioorganic & medicinal chemistry letters, 1999-04, Vol.9 (8), p.1097-1102

1999

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1,4-Cyclohexanecarboxylates: Potent and Selective Inhibitors of Phosophodiesterase 4 for the Treatment of Asthma

Journal of medicinal chemistry, 1998-03, Vol.41 (6), p.821-835

1998

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1-(4-(Naphthalen-2-yl)pyrimidin-2-yl)piperidin-4-ylmethanamine: A Wingless β-Catenin Agonist That Increases Bone Formation Rate

Journal of medicinal chemistry, 2009, Vol.52 (22), p.6962-6965

2009

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1,5-Bis(4-amidinophenoxy) pentane (pentamidine) is a potent inhibitor of [3H]idazoxan binding to imidazoline I2 binding sites

European journal of pharmacology, 1998-07, Vol.353 (1), p.97-103

1998

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1-653 resists degradation in rats

Anesthesia and analgesia, 1988, Vol.67 (6), p.534-538

1988

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'1-8 interferon inducible gene family' : putative colon carcinoma-associated antigens

British journal of cancer, 2007-12, Vol.97 (12), p.1655-1663

2007

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1-Alkyl-8-(piperazine-1-sulfonyl)phenylxanthines: Development and Characterization of Adenosine A2B Receptor Antagonists and a New Radioligand with Subnanomolar Affinity and Subtype Specificity

Journal of medicinal chemistry, 2009-07, Vol.52 (13), p.3994-4006

2009

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A 1- and 2-year follow-up study of bowel sound biofeedback as a treatment for irritable bowel syndrome

Biofeedback and Self-Regulation, 1989-12, Vol.14 (4), p.333-338

1989

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1-Aryl-3-(4-pyridine-2-ylpiperazin-1-yl)propan-1-one Oximes as Potent Dopamine D4 Receptor Agonists for the Treatment of Erectile Dysfunction

Journal of medicinal chemistry, 2006-08, Vol.49 (17), p.5093-5109

2006

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IL-1 has no direct role in the IGF-1 non-responsive state during experimentally induced arthritis in mouse knee joints

Annals of the rheumatic diseases, 1995-12, Vol.54 (12), p.976-982

1995

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1-Methyl-3-phenyl-1,2,4-triazinium-5-olate: a new zwitterion with cytotoxic activity against human cancer cell-lines

Cancer letters, 1988-09, Vol.42 (1), p.29-35

1988

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1,N2-propanodeoxyguanosine adducts : Potential new biomarkers of smoking-induced DNA damage in human oral tissue

Cancer research (Chicago, Ill.), 1998-02, Vol.58 (4), p.581-584

1998

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1,N6-Ethenoadenosine formation, mutagenicity and murine tumor induction as indicators of the generation of an electrophilic epoxide metabolite of the closely related carcinogens ethyl carbamate (urethane) and vinyl carbamate

Carcinogenesis (New York), 1990-03, Vol.11 (3), p.463-473

1990

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0.45% saline and 5% dextrose in water, but not 0.9% saline or 5% dextrose in 0.9% saline, worsen brain edema two hours after closed head trauma in rats two hours after closed head trauma in rats

1-{1-[4-[(N-acetyl-4-piperidinyl)oxy]-2-methoxybenzoyl]piperidin-4-yl}-4H-3,1-benzoxazin-2(1H)-one (L-371,257) : a new, orally bioavailable, non-peptide oxytocin antagonist

1-2-(2,2,2-Trifluoroethoxy)ethyl-1H-pyrazolo[4,3-d]pyrimidines as potent phosphodiesterase 5 (PDE5) inhibitors

1,2,3-Triazolo[5,4-e]1,2,4-triazolo[1,5-c]pyrimidine derivatives: a new class of A2A adenosine receptor antagonists

1-[2-[(5-Cyanopyridin-2-yl)amino]-ethylamino]acetyl-2-(S)-pyrrolidine-carbonitri le: A potent, selective, and orally bioavailable Dipeptidyl peptidase IV inhibitor with antihyperglycemic properties

1,2,5-Thiadiazole Analogues of Aceclidine as Potent m1 Muscarinic Agonists

1,2-Diarylcyclopentenes as Selective Cyclooxygenase-2 Inhibitors and Orally Active Anti-inflammatory Agents

1,25-Dihydroxycalciferol and calcium therapy in osteoporosis with calcium malabsorption. Dose response relationship of calcium absorption and indices of bone turnover

1,25-dihydroxyvitamin D3 inhibits transcription of type I collagen genes in the rat osteosarcoma cell line ROS 17/2.8

1,25-dihydroxyvitamin D3 synthetic analogs inhibit spontaneous metastases in a 1,2-dimethylhydrazine-induced colon carcinogenesis model

1-(3-Cyanobenzylpiperidin-4-yl)-5-methyl-4-phenyl-1,3-dihydroimidazol-2-one : A selective high-affinity antagonist for the human dopamine D4receptor with excellent selectivity over ion channels

1,3-dialkyltriazenes : reactie intermediates and DNA alkylation

1,3-dioxane-4,6-dione-5-carboxamide-based inhibitors of human group IIa phospholipase A2 : X-ray structure of the complex and interfacial selection of inhibitors from a structural library

1,4-Cyclohexanecarboxylates: Potent and Selective Inhibitors of Phosophodiesterase 4 for the Treatment of Asthma

1-(4-(Naphthalen-2-yl)pyrimidin-2-yl)piperidin-4-ylmethanamine: A Wingless β-Catenin Agonist That Increases Bone Formation Rate

1,5-Bis(4-amidinophenoxy) pentane (pentamidine) is a potent inhibitor of [3H]idazoxan binding to imidazoline I2 binding sites

1-653 resists degradation in rats

'1-8 interferon inducible gene family' : putative colon carcinoma-associated antigens

1-Alkyl-8-(piperazine-1-sulfonyl)phenylxanthines: Development and Characterization of Adenosine A2B Receptor Antagonists and a New Radioligand with Subnanomolar Affinity and Subtype Specificity

A 1- and 2-year follow-up study of bowel sound biofeedback as a treatment for irritable bowel syndrome

1-Aryl-3-(4-pyridine-2-ylpiperazin-1-yl)propan-1-one Oximes as Potent Dopamine D4 Receptor Agonists for the Treatment of Erectile Dysfunction

IL-1 has no direct role in the IGF-1 non-responsive state during experimentally induced arthritis in mouse knee joints

1-Methyl-3-phenyl-1,2,4-triazinium-5-olate: a new zwitterion with cytotoxic activity against human cancer cell-lines

1,N2-propanodeoxyguanosine adducts : Potential new biomarkers of smoking-induced DNA damage in human oral tissue

1,N6-Ethenoadenosine formation, mutagenicity and murine tumor induction as indicators of the generation of an electrophilic epoxide metabolite of the closely related carcinogens ethyl carbamate (urethane) and vinyl carbamate

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