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Enhanced Cardiomyocyte NLRP3 Inflammasome Signaling Promotes Atrial Fibrillation

Circulation (New York, N.Y.), 2018-11, Vol.138 (20), p.2227-2242

2018

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Anti-Microtubule Drugs

Methods in molecular biology (Clifton, N.J.), 2016, Vol.1413, p.403

2016

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NLRP3 inflammasome inhibition with MCC950 improves diabetes-mediated cognitive impairment and vasoneuronal remodeling after ischemia

Pharmacological research, 2019-04, Vol.142, p.237-250

2019

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Overview of the anti-inflammatory effects, pharmacokinetic properties and clinical efficacies of arctigenin and arctiin from Arctium lappa L

Acta pharmacologica Sinica, 2018-05, Vol.39 (5), p.787-801

2018

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Enhanced anti-amnestic effect of donepezil by Ginkgo biloba extract (EGb 761) via further improvement in pro-cholinergic and antioxidative activities

Journal of ethnopharmacology, 2021-04, Vol.269, p.113711, Article 113711

2021

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The selective NLRP3 inhibitor MCC950 hinders atherosclerosis development by attenuating inflammation and pyroptosis in macrophages

Scientific reports, 2021-09, Vol.11 (1), p.19305-19305, Article 19305

2021

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Synthesis and evaluation of novel arctigenin derivatives as potential anti-Toxoplasma gondii agents

European journal of medicinal chemistry, 2018-10, Vol.158, p.414-427

2018

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Arctigenin attenuates diabetic kidney disease through the activation of PP2A in podocytes

Nature communications, 2019-10, Vol.10 (1), p.4523-15, Article 4523

2019

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Syringaresinol attenuates sepsis-induced cardiac dysfunction by inhibiting inflammation and pyroptosis in mice

European journal of pharmacology, 2021-12, Vol.913, p.174644-174644, Article 174644

2021

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Arctigenin, a novel TMEM16A inhibitor for lung adenocarcinoma therapy

Pharmacological research, 2020-05, Vol.155, p.104721-104721, Article 104721

2020

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Sesquiterpene lactones from Lychnophora species: Antinociceptive, anti-inflammatory, and antioxidant pathways to treat acute gout

Journal of ethnopharmacology, 2021-04, Vol.269, p.113738, Article 113738

2021

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Recent Advances in the Development of Antineoplastic Agents Derived from Natural Products

Drugs (New York, N.Y.), 2015-11, Vol.75 (17), p.1993-2016

Trendowski, Matthew

2015

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Design and Synthesis of 4‑Fluorophenyl-5-methylene-2(5H)‑furanone Derivatives as Potent Quorum Sensing Inhibitors

Journal of medicinal chemistry, 2023-07, Vol.66 (13), p.8441-8463

2023

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Arctigenin, an anti-tumor agent; a cutting-edge topic and up-to-the-minute approach in cancer treatment

European journal of pharmacology, 2021-10, Vol.909, p.174419-174419, Article 174419

2021

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The Antinociceptive Activity of (E)-3-(thiophen-2-yl)- N -(p-tolyl)acrylamide in Mice Is Reduced by (E)-3-(furan-2-yl)- N -methyl- N -(p-tolyl)acrylamide Through Opposing Modulatory Mechanisms at the α7 Nicotinic Acetylcholine Receptor

Anesthesia and analgesia, 2023-09, Vol.137 (3), p.691

2023

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Arctiin protects rat heart against ischemia/reperfusion injury via a mechanism involving reduction of necroptosis

European journal of pharmacology, 2020-05, Vol.875, p.173053-173053, Article 173053

2020

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Effect of arctigenin on neurological diseases: A review

Journal of ethnopharmacology, 2023-10, Vol.315, p.116642-116642, Article 116642

2023

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Blockade of the NLRP3/caspase-1 axis attenuates ketamine-induced hippocampus pyroptosis and cognitive impairment in neonatal rats

Journal of neuroinflammation, 2021-10, Vol.18 (1), p.239-239, Article 239

2021

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Structure-based design and synthesis of sulfonylureas as novel NLRP3 inhibitors for Alzheimer’s disease

Bioorganic & medicinal chemistry letters, 2024-02, Vol.99, p.129622-129622, Article 129622

2024

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Discovery of antitumor anthra[2,3-b]furan-3-carboxamides: Optimization of synthesis and evaluation of antitumor properties

European journal of medicinal chemistry, 2016-04, Vol.112, p.114-129

2016

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Atractylodin ameliorates lipopolysaccharide-induced depressive-like behaviors in mice through reducing neuroinflammation and neuronal damage

Journal of neuroimmunology, 2024-05, Vol.390, p.578349-578349, Article 578349

2024

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Arctigenin induces activated HSCs quiescence via AMPK-PPARγ pathway to ameliorate liver fibrosis in mice

European journal of pharmacology, 2024-07, Vol.974, p.176629-176629, Article 176629

2024

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Selective Inhibition of NLRP3 Inflammasome Reverses Pressure Overload-Induced Pathological Cardiac Remodeling by Attenuating Hypertrophy, Fibrosis, and Inflammation

International immunopharmacology, 2021-10, Vol.99, p.108046-108046, Article 108046

2021

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Phosphoinositide 3-Kinase (PI3K) Reactive Oxygen Species (ROS)-Activated Prodrug in Combination with Anthracycline Impairs PI3K Signaling, Increases DNA Damage Response and Reduces Breast Cancer Cell Growth

International journal of molecular sciences, 2021-02, Vol.22 (4), p.2088

2021

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Eribulin induces tumor vascular remodeling through intussusceptive angiogenesis in a sarcoma xenograft model

Biochemical and biophysical research communications, 2021-09, Vol.570, p.89-95

2021

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Enhanced Cardiomyocyte NLRP3 Inflammasome Signaling Promotes Atrial Fibrillation

Anti-Microtubule Drugs

NLRP3 inflammasome inhibition with MCC950 improves diabetes-mediated cognitive impairment and vasoneuronal remodeling after ischemia

Overview of the anti-inflammatory effects, pharmacokinetic properties and clinical efficacies of arctigenin and arctiin from Arctium lappa L

Enhanced anti-amnestic effect of donepezil by Ginkgo biloba extract (EGb 761) via further improvement in pro-cholinergic and antioxidative activities

The selective NLRP3 inhibitor MCC950 hinders atherosclerosis development by attenuating inflammation and pyroptosis in macrophages

Synthesis and evaluation of novel arctigenin derivatives as potential anti-Toxoplasma gondii agents

Arctigenin attenuates diabetic kidney disease through the activation of PP2A in podocytes

Syringaresinol attenuates sepsis-induced cardiac dysfunction by inhibiting inflammation and pyroptosis in mice

Arctigenin, a novel TMEM16A inhibitor for lung adenocarcinoma therapy

Sesquiterpene lactones from Lychnophora species: Antinociceptive, anti-inflammatory, and antioxidant pathways to treat acute gout

Recent Advances in the Development of Antineoplastic Agents Derived from Natural Products

Design and Synthesis of 4‑Fluorophenyl-5-methylene-2(5H)‑furanone Derivatives as Potent Quorum Sensing Inhibitors

Arctigenin, an anti-tumor agent; a cutting-edge topic and up-to-the-minute approach in cancer treatment

The Antinociceptive Activity of (E)-3-(thiophen-2-yl)- N -(p-tolyl)acrylamide in Mice Is Reduced by (E)-3-(furan-2-yl)- N -methyl- N -(p-tolyl)acrylamide Through Opposing Modulatory Mechanisms at the α7 Nicotinic Acetylcholine Receptor

Arctiin protects rat heart against ischemia/reperfusion injury via a mechanism involving reduction of necroptosis

Effect of arctigenin on neurological diseases: A review

Blockade of the NLRP3/caspase-1 axis attenuates ketamine-induced hippocampus pyroptosis and cognitive impairment in neonatal rats

Structure-based design and synthesis of sulfonylureas as novel NLRP3 inhibitors for Alzheimer’s disease

Discovery of antitumor anthra[2,3-b]furan-3-carboxamides: Optimization of synthesis and evaluation of antitumor properties

Atractylodin ameliorates lipopolysaccharide-induced depressive-like behaviors in mice through reducing neuroinflammation and neuronal damage

Arctigenin induces activated HSCs quiescence via AMPK-PPARγ pathway to ameliorate liver fibrosis in mice

Selective Inhibition of NLRP3 Inflammasome Reverses Pressure Overload-Induced Pathological Cardiac Remodeling by Attenuating Hypertrophy, Fibrosis, and Inflammation

Phosphoinositide 3-Kinase (PI3K) Reactive Oxygen Species (ROS)-Activated Prodrug in Combination with Anthracycline Impairs PI3K Signaling, Increases DNA Damage Response and Reduces Breast Cancer Cell Growth

Eribulin induces tumor vascular remodeling through intussusceptive angiogenesis in a sarcoma xenograft model

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