UB Paderborn / Katalog / Suche / in CDI

Sortiert nach

Einfacher Volltextzugriff von (fast) überall

Installieren Sie die LibKey Nomad-Browsererweiterung und erhalten Sie von vielen Webseiten einfachen Zugriff auf lizenzierte Volltexte oder Open Access Publikationen. Mehr erfahren...

Use of Phenoxyaniline Analogues To Generate Biochemical Insights into the Interactio n of Polybrominated Diphenyl Ether with CYP2B Enzymes

Biochemistry (Easton), 2018-02, Vol.57 (5), p.817-826

2018

Volltextzugriff (PDF)

CYP induction-mediated drug interactions: in vitro assessment and clinical implications

Pharmaceutical research, 2006-06, Vol.23 (6), p.1089-1116

Lin, Jiunn H

2006

Volltextzugriff (PDF)

Peroxisome Proliferator‐Activated Receptor α Activation Suppresses Cytochrome P450 Induction Potential in Mice Treated with Gemfibrozil

Basic & clinical pharmacology & toxicology, 2017-09, Vol.121 (3), p.169-174

2017

Volltextzugriff (PDF)

Bromuconazole-induced hepatotoxicity is accompanied by upregulation of PXR/CYP3A1 and downregulation of CAR/CYP2B1 gene expression

Toxicology mechanisms and methods, 2017-09, Vol.27 (7), p.544-550

2017

Volltextzugriff (PDF)

Characterization of metabolites and cytochrome P450 isoforms involved in the microsomal metabolism of aconitine

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2006-12, Vol.844 (2), p.292-300

2006

Volltextzugriff (PDF)

Brain Drug-Metabolizing Cytochrome P450 Enzymes are Active In Vivo, Demonstrated by Mechanism-Based Enzyme Inhibition

Neuropsychopharmacology (New York, N.Y.), 2009-02, Vol.34 (3), p.634-640

2009

Volltextzugriff (PDF)

Directed evolution of mammalian cytochrome P450 2B1: mutations outside of the active site enhance the metabolism of several substrates, including the anticancer prodrugs cyclophosphamide and ifosfamide

The Journal of biological chemistry, 2005-05, Vol.280 (20), p.19569

2005

Volltextzugriff (PDF)

Brain tumor oncolysis with replication-conditional herpes simplex virus type 1 expressing the prodrug-activating genes, CYP2B1 and secreted human intestinal carboxylesterase, in combination with cyclophosphamide and irinotecan

Cancer research (Chicago, Ill.), 2005-08, Vol.65 (15), p.6850-6857

2005

Volltextzugriff (PDF)

Biologically relevant reductions in fetal testosterone and Insl3 induced by in utero exposure to high levels of di-isononyl phthalate (DINP) in male rats

Toxicology and applied pharmacology, 2023-04, Vol.465, p.116454-116454, Article 116454

Earl Gray, L.

2023

Volltextzugriff (PDF)

Beta sheet 2–alpha helix C loop of cytochrome P450 reductase serves as a docking site for redox partners

Biochimica et biophysica acta, 2010-06, Vol.1804 (6), p.1285-1293

2010

Volltextzugriff (PDF)

Novel cudraisoflavone J derivatives as potent neuroprotective agents for the treatment of Parkinson's disease via the activation of Nrf2/HO-1 signaling

European journal of medicinal chemistry, 2022-11, Vol.242, p.114692, Article 114692

2022

Volltextzugriff (PDF)

Engineering mammalian cytochrome P450 2B1 by directed evolution for enhanced catalytic tolerance to temperature and dimethyl sulfoxide

Protein engineering, design and selection, 2006-12, Vol.19 (12), p.547-554

2006

Volltextzugriff (PDF)

Cytochrome P450 2B1 Mediates Complement-dependent Sublytic Injury in a Model of Membranous Nephropathy

The Journal of biological chemistry, 2010-12, Vol.285 (52), p.40901-40910

2010

Volltextzugriff (PDF)

Effect of 17-alpha-ethynylestradiol on activities of cytochrome P450 2B (P450 2B) enzymes: characterization of inactivation of P450s 2B1 and 2B6 and identification of metabolites

The Journal of pharmacology and experimental therapeutics, 2002-02, Vol.300 (2), p.549-558

2002

Volltextzugriff (PDF)

Mechanism-based inactivation of CYP2B1 and its F-helix mutant by two tert-butyl acetylenic compounds: covalent modification of prosthetic heme versus apoprotein

The Journal of pharmacology and experimental therapeutics, 2009-11, Vol.331 (2), p.392-403

2009

Volltextzugriff (PDF)

Structure-Function Analysis of Mammalian CYP2B Enzymes Using 7-Substituted Coumarin Derivatives as Probes: Utility of Crystal Structures and Molecular Modeling in Understanding Xenobiotic Metabolism

Molecular pharmacology, 2016-04, Vol.89 (4), p.435-445

2016

Volltextzugriff (PDF)

Chinese herbal formula Fuzheng Huayu alleviates CCl 4 -induced liver fibrosis in rats: a transcriptomic and proteomic analysis

Acta pharmacologica Sinica, 2018-06, Vol.39 (6), p.930

2018

Volltextzugriff (PDF)

Subacute nicotine co-exposure has no effect on 2,2′,3,5′,6- pentachlorobiphenyl disposition but alters hepatic cytochrome P450 expression in the male rat

Toxicology (Amsterdam), 2015-12, Vol.338, p.59-68

2015

Volltextzugriff (PDF)

Identification of 17-α-Ethynylestradiol-Modified Active Site Peptides and Glutathione Conjugates Formed during Metabolism and Inactivation of P450s 2B1 and 2B6

Chemical research in toxicology, 2006-02, Vol.19 (2), p.279-287

2006

Volltextzugriff (PDF)

Dual targeting of cytochrome P4502B1 to endoplasmic reticulum and mitochondria involves a novel signal activation by cyclic AMP-dependent phosphorylation at Ser128

The EMBO journal, 1999-10, Vol.18 (20), p.5494-5504

1999

Volltextzugriff (PDF)

Modification of Serine 360 by a Reactive Intermediate of 17-α-Ethynylestradiol Results in Mechanism-Based Inactivation of Cytochrome P450s 2B1 and 2B6

Chemical research in toxicology, 2008-10, Vol.21 (10), p.1956-1963

2008

Volltextzugriff (PDF)

Mechanism-Based Inactivation of Human Cytochrome P450 2B6 by Chlorpyrifos

Chemical research in toxicology, 2015-07, Vol.28 (7), p.1484-1495

2015

Volltextzugriff (PDF)

Proteasome-dependent degradation of cytochromes P450 2E1 and 2B1 expressed in tetracycline-regulated HeLa cells

Toxicology and applied pharmacology, 2004-09, Vol.199 (3), p.332-343

2004

Volltextzugriff (PDF)

Unmasking efavirenz neurotoxicity: Time matters to the underlying mechanisms

European journal of pharmaceutical sciences, 2017-07, Vol.105, p.47-54

2017

Volltextzugriff (PDF)

Functional role of residues in the helix B′ region of cytochrome P450 2B1

Archives of biochemistry and biophysics, 2005-03, Vol.435 (1), p.157-165

2005

Volltextzugriff (PDF)

1 – 25 von 780

Suche als RSS-Feed

Aktive Filter

SpracheDeutsch

ThemaFemale

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(746)
Mit Volltextzugriff
(660)

Publikationsform

Artikel
(780)

Sprache

Erscheinungsjahr

n.n

Thema

Animals
(721)
Science & Technology
(590)
Life Sciences & Biomedicine
(586)
Rats
(576)
Male
(503)
Cytochrome P-450 Cyp2b1 - Metabolism
(380)
Biological And Medical Sciences
(360)
Medical Sciences
(276)
Toxicology
(254)
Cytochrome P-450 Enzyme System - Metabolism
(252)
Pharmacology & Pharmacy
(221)
Liver - Enzymology
(214)
Microsomes, Liver - Enzymology
(208)
Liver - Drug Effects
(196)
Cytochrome P-450 Cyp2b1 - Genetics
(186)
Rats, Sprague-Dawley
(183)
Cytochrome P450
(178)
Cytochrome P-450 Cyp2b1
(166)
Phenobarbital - Pharmacology
(154)
Cytochrome P-450 Cyp1a1 - Metabolism
(150)

15 weitere anzeigen...

Weniger anzeigen...

Zeitschrift / Serie

5 weitere anzeigen...

Weniger anzeigen...

Menü

Weitere Dienste

Einstellungen

Use of Phenoxyaniline Analogues To Generate Biochemical Insights into the Interactio n of Polybrominated Diphenyl Ether with CYP2B Enzymes

CYP induction-mediated drug interactions: in vitro assessment and clinical implications

Peroxisome Proliferator‐Activated Receptor α Activation Suppresses Cytochrome P450 Induction Potential in Mice Treated with Gemfibrozil

Bromuconazole-induced hepatotoxicity is accompanied by upregulation of PXR/CYP3A1 and downregulation of CAR/CYP2B1 gene expression

Characterization of metabolites and cytochrome P450 isoforms involved in the microsomal metabolism of aconitine

Brain Drug-Metabolizing Cytochrome P450 Enzymes are Active In Vivo, Demonstrated by Mechanism-Based Enzyme Inhibition

Directed evolution of mammalian cytochrome P450 2B1: mutations outside of the active site enhance the metabolism of several substrates, including the anticancer prodrugs cyclophosphamide and ifosfamide

Brain tumor oncolysis with replication-conditional herpes simplex virus type 1 expressing the prodrug-activating genes, CYP2B1 and secreted human intestinal carboxylesterase, in combination with cyclophosphamide and irinotecan

Biologically relevant reductions in fetal testosterone and Insl3 induced by in utero exposure to high levels of di-isononyl phthalate (DINP) in male rats

Beta sheet 2–alpha helix C loop of cytochrome P450 reductase serves as a docking site for redox partners

Novel cudraisoflavone J derivatives as potent neuroprotective agents for the treatment of Parkinson's disease via the activation of Nrf2/HO-1 signaling

Engineering mammalian cytochrome P450 2B1 by directed evolution for enhanced catalytic tolerance to temperature and dimethyl sulfoxide

Cytochrome P450 2B1 Mediates Complement-dependent Sublytic Injury in a Model of Membranous Nephropathy

Effect of 17-alpha-ethynylestradiol on activities of cytochrome P450 2B (P450 2B) enzymes: characterization of inactivation of P450s 2B1 and 2B6 and identification of metabolites

Mechanism-based inactivation of CYP2B1 and its F-helix mutant by two tert-butyl acetylenic compounds: covalent modification of prosthetic heme versus apoprotein

Structure-Function Analysis of Mammalian CYP2B Enzymes Using 7-Substituted Coumarin Derivatives as Probes: Utility of Crystal Structures and Molecular Modeling in Understanding Xenobiotic Metabolism

Chinese herbal formula Fuzheng Huayu alleviates CCl 4 -induced liver fibrosis in rats: a transcriptomic and proteomic analysis

Subacute nicotine co-exposure has no effect on 2,2′,3,5′,6- pentachlorobiphenyl disposition but alters hepatic cytochrome P450 expression in the male rat

Identification of 17-α-Ethynylestradiol-Modified Active Site Peptides and Glutathione Conjugates Formed during Metabolism and Inactivation of P450s 2B1 and 2B6

Dual targeting of cytochrome P4502B1 to endoplasmic reticulum and mitochondria involves a novel signal activation by cyclic AMP-dependent phosphorylation at Ser128

Modification of Serine 360 by a Reactive Intermediate of 17-α-Ethynylestradiol Results in Mechanism-Based Inactivation of Cytochrome P450s 2B1 and 2B6

Mechanism-Based Inactivation of Human Cytochrome P450 2B6 by Chlorpyrifos

Proteasome-dependent degradation of cytochromes P450 2E1 and 2B1 expressed in tetracycline-regulated HeLa cells

Unmasking efavirenz neurotoxicity: Time matters to the underlying mechanisms

Functional role of residues in the helix B′ region of cytochrome P450 2B1

Aktive Filter

Suchergebnisse filtern