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SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy

Cancer cell, 2020-06, Vol.37 (6), p.834-849.e13

2020

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RNA cytosine methylation by Dnmt2 and NSun2 promotes tRNA stability and protein synthesis

Nature structural & molecular biology, 2012-09, Vol.19 (9), p.900-905

2012

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De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes

Nature structural & molecular biology, 2008-11, Vol.15 (11), p.1176-1183

2008

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Arginine and lysine methylation of MRPS23 promotes breast cancer metastasis through regulating OXPHOS

Oncogene, 2021-05, Vol.40 (20), p.3548-3563

2021

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A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin

Genes & development, 2004-06, Vol.18 (11), p.1251-1262

2004

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Activation of Endogenous Retroviruses in Dnmt1−/− ESCs Involves Disruption of SETDB1-Mediated Repression by NP95 Binding to Hemimethylated DNA

Cell stem cell, 2016-07, Vol.19 (1), p.81-94

2016

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CRL4B promotes tumorigenesis by coordinating with SUV39H1/HP1/DNMT3A in DNA methylation-based epigenetic silencing

Oncogene, 2015-01, Vol.34 (1), p.104-118

2015

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Protein arginine methyltransferase 5-mediated epigenetic silencing of IRX1 contributes to tumorigenicity and metastasis of gastric cancer

Biochimica et biophysica acta. Molecular basis of disease, 2018-09, Vol.1864 (9), p.2835-2844

2018

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Altered DNA methylation and Dnmt expression in obese uterus may cause implantation failure

Journal of molecular histology, 2024-08, Vol.55 (4), p.427-436

2024

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Liver‐specific deletion of de novo DNA methyltransferases protects against glucose intolerance in high‐fat diet‐fed male mice

The FASEB journal, 2024-05, Vol.38 (10), p.e23690-n/a

2024

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The Role of DNMT and HDACs in the Fetal Programming of Hypertension by Glucocorticoids

Oxidative medicine and cellular longevity, 2020, Vol.2020 (2020), p.1-17

2020

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Histone Methyltransferase KMT2D Regulates H3K4 Methylation and is Involved in the Pathogenesis of Ovarian Cancer

Cell transplantation, 2021, Vol.30, p.9636897211027521-9636897211027521

2021

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The Sm-Protein Methyltransferase, Dart5, Is Essential for Germ-Cell Specification and Maintenance

Current biology, 2006-06, Vol.16 (11), p.1077-1089

2006

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Evaluating the role of DNA methyltransferases in trophoblast fusion and preeclampsia development: Insights from methylation‐regulated genes

The FASEB journal, 2024-07, Vol.38 (13), p.e23706-n/a

2024

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The histone chaperone CAF-1 cooperates with the DNA methyltransferases to maintain Cd4 silencing in cytotoxic T cells

Genes & development, 2019-06, Vol.33 (11-12), p.669-683

2019

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RAMP2-AS1 inhibits CXCL11 expression to suppress malignant phenotype of breast cancer by recruiting DNMT1 and DNMT3B

Experimental cell research, 2022-07, Vol.416 (2), p.113139-113139, Article 113139

2022

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A loop involving NRF2, miR‐29b‐1‐5p and AKT, regulates cell fate of MDA‐MB‐231 triple‐negative breast cancer cells

Journal of cellular physiology, 2020-02, Vol.235 (2), p.629-637

2020

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Downregulation of UBB potentiates SP1/VEGFA-dependent angiogenesis in clear cell renal cell carcinoma

Oncogene, 2024-05, Vol.43 (18), p.1386-1396

2024

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The loss of RNA N 6 -adenosine methyltransferase Mettl14 in tumor-associated macrophages promotes CD8 + T cell dysfunction and tumor growth

Cancer cell, 2021-07, Vol.39 (7), p.945

2021

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pRb2/p130-E2F4/5-HDAC1-SUV39H1-p300 and pRb2/p130-E2F4/5-HDAC1-SUV39H1-DNMT1 multimolecular complexes mediate the transcription of estrogen receptor-α in breast cancer

Oncogene, 2003-06, Vol.22 (23), p.3511-3517

2003

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DNMT1, DNMT3A and DNMT3B proteins are differently expressed in mouse oocytes and early embryos

Journal of molecular histology, 2017-12, Vol.48 (5-6), p.417-426

2017

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FGF10 enhances yak oocyte fertilization competence and subsequent blastocyst quality and regulates the levels of CD9, CD81, DNMT1, and DNMT3B

Journal of cellular physiology, 2019-10, Vol.234 (10), p.17677-17689

2019

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The frequency of CpG and non-CpG methylation of Notch3 gene promoter determines its expression levels in breast cancer cells

Experimental cell research, 2020-01, Vol.386 (2), p.111743, Article 111743

2020

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Inhibition of METTL3 attenuates renal injury and inflammation by alleviating TAB3 m6A modifications via IGF2BP2-dependent mechanisms

Science translational medicine, 2022-04, Vol.14 (640), p.eabk2709

2022

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SETDB1-mediated methylation of Akt promotes its K63-linked ubiquitination and activation leading to tumorigenesis

Nature cell biology, 2019-02, Vol.21 (2), p.214-225

2019

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SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy

RNA cytosine methylation by Dnmt2 and NSun2 promotes tRNA stability and protein synthesis

De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes

Arginine and lysine methylation of MRPS23 promotes breast cancer metastasis through regulating OXPHOS

A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin

Activation of Endogenous Retroviruses in Dnmt1−/− ESCs Involves Disruption of SETDB1-Mediated Repression by NP95 Binding to Hemimethylated DNA

CRL4B promotes tumorigenesis by coordinating with SUV39H1/HP1/DNMT3A in DNA methylation-based epigenetic silencing

Protein arginine methyltransferase 5-mediated epigenetic silencing of IRX1 contributes to tumorigenicity and metastasis of gastric cancer

Altered DNA methylation and Dnmt expression in obese uterus may cause implantation failure

Liver‐specific deletion of de novo DNA methyltransferases protects against glucose intolerance in high‐fat diet‐fed male mice

The Role of DNMT and HDACs in the Fetal Programming of Hypertension by Glucocorticoids

Histone Methyltransferase KMT2D Regulates H3K4 Methylation and is Involved in the Pathogenesis of Ovarian Cancer

The Sm-Protein Methyltransferase, Dart5, Is Essential for Germ-Cell Specification and Maintenance

Evaluating the role of DNA methyltransferases in trophoblast fusion and preeclampsia development: Insights from methylation‐regulated genes

The histone chaperone CAF-1 cooperates with the DNA methyltransferases to maintain Cd4 silencing in cytotoxic T cells

RAMP2-AS1 inhibits CXCL11 expression to suppress malignant phenotype of breast cancer by recruiting DNMT1 and DNMT3B

A loop involving NRF2, miR‐29b‐1‐5p and AKT, regulates cell fate of MDA‐MB‐231 triple‐negative breast cancer cells

Downregulation of UBB potentiates SP1/VEGFA-dependent angiogenesis in clear cell renal cell carcinoma

The loss of RNA N 6 -adenosine methyltransferase Mettl14 in tumor-associated macrophages promotes CD8 + T cell dysfunction and tumor growth

pRb2/p130-E2F4/5-HDAC1-SUV39H1-p300 and pRb2/p130-E2F4/5-HDAC1-SUV39H1-DNMT1 multimolecular complexes mediate the transcription of estrogen receptor-α in breast cancer

DNMT1, DNMT3A and DNMT3B proteins are differently expressed in mouse oocytes and early embryos

FGF10 enhances yak oocyte fertilization competence and subsequent blastocyst quality and regulates the levels of CD9, CD81, DNMT1, and DNMT3B

The frequency of CpG and non-CpG methylation of Notch3 gene promoter determines its expression levels in breast cancer cells

Inhibition of METTL3 attenuates renal injury and inflammation by alleviating TAB3 m6A modifications via IGF2BP2-dependent mechanisms

SETDB1-mediated methylation of Akt promotes its K63-linked ubiquitination and activation leading to tumorigenesis

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