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Dorothy Hodgkin Lecture 2014 Understanding genes identified by genome-wide association studies for Type 2 diabetes

Diabetic medicine, 2014-12, Vol.31 (12), p.1480-1487

Rutter, G. A.

2014

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Beta cell-specific Znt8 deletion in mice causes marked defects in insulin processing, crystallisation and secretion

Diabetologia, 2010-08, Vol.53 (8), p.1656-1668

2010

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Increased expression of miR-187 in human islets from individuals with type 2 diabetes is associated with reduced glucose-stimulated insulin secretion

Diabetologia, 2014-01, Vol.57 (1), p.122-128

2014

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Abnormal glucose tolerance and insulin secretion in pancreas-specific Tcf7l2-null mice

Diabetologia, 2012-10, Vol.55 (10), p.2667-2676

2012

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Insulin crystallization depends on zinc transporter ZnT8 expression, but is not required for normal glucose homeostasis in mice

Proceedings of the National Academy of Sciences - PNAS, 2009-09, Vol.106 (35), p.14872-14877

2009

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Inhibition by glucose or leptin of hypothalamic neurons expressing neuropeptide Y requires changes in AMP-activated protein kinase activity

Diabetologia, 2007-01, Vol.50 (1), p.168-177

2007

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Glutamine potently stimulates glucagon-like peptide-1 secretion from GLUTag cells

Diabetologia, 2004-09, Vol.47 (9), p.1592-1601

2004

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Visualising insulin secretion. The Minkowski Lecture 2004

Diabetologia, 2004-11, Vol.47 (11), p.1861-1872

RUTTER, G. A

2004

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Per-arnt-sim (PAS) domain-containing protein kinase is downregulated in human islets in type 2 diabetes and regulates glucagon secretion

Diabetologia, 2011-04, Vol.54 (4), p.819-827

2011

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AMP-activated protein kinase regulates glucagon secretion from mouse pancreatic alpha cells

Diabetologia, 2011-01, Vol.54 (1), p.125-134

2011

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An alternative polyadenylation signal in TCF7L2 generates isoforms that inhibit T cell factor/lymphoid-enhancer factor (TCF/LEF)-dependent target genes

Diabetologia, 2011-12, Vol.54 (12), p.3078-3082

2011

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Over-expression of AMP-activated protein kinase impairs pancreatic β-cell function in vivo

Journal of endocrinology, 2005-11, Vol.187 (2), p.225-235

2005

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Acute overexpression of lactate dehydrogenase-A perturbs beta-cell mitochondrial metabolism and insulin secretion

Diabetes (New York, N.Y.), 2000-07, Vol.49 (7), p.1149-1155

2000

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When less is more: the forbidden fruits of gene repression in the adult β-cell

Diabetes, obesity & metabolism, 2013-06, Vol.15 (6), p.503-512

2013

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Variance stabilization and normalization for one-color microarray data using a data-driven multiscale approach

Bioinformatics, 2006-10, Vol.22 (20), p.2547-2553

2006

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A red-shifted photochromic sulfonylurea for the remote control of pancreatic beta cell function

Chemical communications (Cambridge, England), 2015-04, Vol.51 (27), p.6018-6021

2015

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Intracellular ATP-sensitive K+ channels in mouse pancreatic beta cells : against a role in organelle cation homeostasis

Diabetologia, 2006-07, Vol.49 (7), p.1567-1577

2006

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Intra-islet glucagon signalling regulates beta-cell connectivity, first-phase insulin secretion and glucose homoeostasis

Molecular metabolism (Germany), 2024-07, Vol.85, p.101947, Article 101947

2024

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Ablation of AMP-activated protein kinase α1 and α2 from mouse pancreatic beta cells and RIP2.Cre neurons suppresses insulin release in vivo

Diabetologia, 2010-05, Vol.53 (5), p.924-936

2010

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Ablation of AMP-activated protein kinase alpha 1 and alpha 2 from mouse pancreatic beta cells and RIP2.Cre neurons suppresses insulin release in vivo

Diabetologia, 2010-05, Vol.53 (5), p.924-936

2010

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Physical Exercise–Induced Hypoglycemia Caused by Failed Silencing of Monocarboxylate Transporter 1 in Pancreatic β Cells

American journal of human genetics, 2007-09, Vol.81 (3), p.467-474

2007

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Pancreatic β-cell imaging in humans: fiction or option?

Diabetes, obesity & metabolism, 2016-01, Vol.18 (1), p.6-15

2016

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Stimulated Ca2+ influx raises mitochondrial free Ca2+ to supramicromolar levels in a pancreatic beta-cell line. Possible role in glucose and agonist-induced insulin secretion

The Journal of biological chemistry, 1993-10, Vol.268 (30), p.22385-22390

1993

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Subcellular Imaging of Intramitochondrial Ca2+ with Recombinant Targeted Aequorin: Significance for the Regulation of Pyruvate Dehydrogenase Activity

Proceedings of the National Academy of Sciences - PNAS, 1996-05, Vol.93 (11), p.5489-5494

1996

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Regulation of Gene Expression by Glucose in Pancreatic β-Cells (MIN6) via Insulin Secretion and Activation of Phosphatidylinositol 3′-Kinase

The Journal of biological chemistry, 2000-11, Vol.275 (46), p.36269-36277

2000

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Dorothy Hodgkin Lecture 2014 Understanding genes identified by genome-wide association studies for Type 2 diabetes

Beta cell-specific Znt8 deletion in mice causes marked defects in insulin processing, crystallisation and secretion

Increased expression of miR-187 in human islets from individuals with type 2 diabetes is associated with reduced glucose-stimulated insulin secretion

Abnormal glucose tolerance and insulin secretion in pancreas-specific Tcf7l2-null mice

Insulin crystallization depends on zinc transporter ZnT8 expression, but is not required for normal glucose homeostasis in mice

Inhibition by glucose or leptin of hypothalamic neurons expressing neuropeptide Y requires changes in AMP-activated protein kinase activity

Glutamine potently stimulates glucagon-like peptide-1 secretion from GLUTag cells

Visualising insulin secretion. The Minkowski Lecture 2004

Per-arnt-sim (PAS) domain-containing protein kinase is downregulated in human islets in type 2 diabetes and regulates glucagon secretion

AMP-activated protein kinase regulates glucagon secretion from mouse pancreatic alpha cells

An alternative polyadenylation signal in TCF7L2 generates isoforms that inhibit T cell factor/lymphoid-enhancer factor (TCF/LEF)-dependent target genes

Over-expression of AMP-activated protein kinase impairs pancreatic β-cell function in vivo

Acute overexpression of lactate dehydrogenase-A perturbs beta-cell mitochondrial metabolism and insulin secretion

When less is more: the forbidden fruits of gene repression in the adult β-cell

Variance stabilization and normalization for one-color microarray data using a data-driven multiscale approach

A red-shifted photochromic sulfonylurea for the remote control of pancreatic beta cell function

Intracellular ATP-sensitive K+ channels in mouse pancreatic beta cells : against a role in organelle cation homeostasis

Intra-islet glucagon signalling regulates beta-cell connectivity, first-phase insulin secretion and glucose homoeostasis

Ablation of AMP-activated protein kinase α1 and α2 from mouse pancreatic beta cells and RIP2.Cre neurons suppresses insulin release in vivo

Ablation of AMP-activated protein kinase alpha 1 and alpha 2 from mouse pancreatic beta cells and RIP2.Cre neurons suppresses insulin release in vivo

Physical Exercise–Induced Hypoglycemia Caused by Failed Silencing of Monocarboxylate Transporter 1 in Pancreatic β Cells

Pancreatic β-cell imaging in humans: fiction or option?

Stimulated Ca2+ influx raises mitochondrial free Ca2+ to supramicromolar levels in a pancreatic beta-cell line. Possible role in glucose and agonist-induced insulin secretion

Subcellular Imaging of Intramitochondrial Ca2+ with Recombinant Targeted Aequorin: Significance for the Regulation of Pyruvate Dehydrogenase Activity

Regulation of Gene Expression by Glucose in Pancreatic β-Cells (MIN6) via Insulin Secretion and Activation of Phosphatidylinositol 3′-Kinase

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