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Non-catalytic role of phosphoinositide 3-kinase in mesenchymal cell migration through non-canonical induction of p85β/AP2-mediated endocytosis

Nature communications, 2024-03, Vol.15 (1), p.2612-2612

2024

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Phosphoinositide 3-kinase p110δ promotes lumen formation through the enhancement of apico-basal polarity and basal membrane organization

Nature communications, 2015-01, Vol.6 (1), p.5937-5937, Article 5937

2015

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A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria

Nature (London), 2015-04, Vol.520 (7549), p.683-687

2015

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Characterisation of a cyclic peptide that binds to the RAS binding domain of phosphoinositide 3-kinase p110α

Scientific reports, 2023-02, Vol.13 (1), p.1889-1889, Article 1889

2023

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At a crossroads: how to translate the roles of PI3K in oncogenic and metabolic signalling into improvements in cancer therapy

Nature reviews. Clinical oncology, 2022-07, Vol.19 (7), p.471-485

2022

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The role of PI3Kγ in the immune system: new insights and translational implications

Nature reviews. Immunology, 2022-11, Vol.22 (11), p.687

2022

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Phosphatidylinositol 3-kinase p110δ drives intestinal fibrosis in SHIP deficiency

Mucosal immunology, 2019-09, Vol.12 (5), p.1187-1200

2019

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Pan-cancer analysis on the role of PIK3R1 and PIK3R2 in human tumors

Scientific reports, 2022-04, Vol.12 (1), p.5924-5924, Article 5924

2022

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The interleukin-33-mediated inhibition of expression of two key genes implicated in atherosclerosis in human macrophages requires MAP kinase, phosphoinositide 3-kinase and nuclear factor-κB signaling pathways

Scientific reports, 2019-08, Vol.9 (1), p.11317-12, Article 11317

2019

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Deficiency in class III PI3-kinase confers postnatal lethality with IBD-like features in zebrafish

Nature communications, 2018-07, Vol.9 (1), p.2639-13, Article 2639

2018

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TLR9 and beclin 1 crosstalk regulates muscle AMPK activation in exercise

Nature (London), 2020-02, Vol.578 (7796), p.605-609

2020

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The present and future of PI3K inhibitors for cancer therapy

Nature cancer, 2021-06, Vol.2 (6), p.587

2021

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Identification of the Binding Sites on Rab5 and p110beta Phosphatidylinositol 3-kinase

Scientific reports, 2017-11, Vol.7 (1), p.16194-13, Article 16194

2017

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Autophagy restricts proliferation driven by oncogenic phosphatidylinositol 3-kinase in three-dimensional culture

Oncogene, 2013-05, Vol.32 (20), p.2543-2554

2013

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A conserved mechanism of TOR-dependent RCK-mediated mRNA degradation regulates autophagy

Nature cell biology, 2015-07, Vol.17 (7), p.930

2015

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A class of highly selective inhibitors bind to an active state of PI3Kγ

Nature chemical biology, 2019-04, Vol.15 (4), p.348

2019

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Development and characterisation of a panel of phosphatidylinositide 3-kinase - mammalian target of rapamycin inhibitor resistant lung cancer cell lines

Scientific reports, 2018-01, Vol.8 (1), p.1652-12, Article 1652

2018

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p85α recruitment by the CD300f phosphatidylserine receptor mediates apoptotic cell clearance required for autoimmunity suppression

Nature communications, 2014-01, Vol.5 (1), p.3146-3146, Article 3146

2014

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A novel lncRNA LNC_000052 leads to the dysfunction of osteoporotic BMSCs via the miR-96-5p-PIK3R1 axis

Cell death & disease, 2020-09, Vol.11 (9), p.795-795, Article 795

2020

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PI3Kβ controls immune evasion in PTEN-deficient breast tumours

Nature (London), 2023-05, Vol.617 (7959), p.139-146

2023

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Addiction to the IGF2-ID1-IGF2 circuit for maintenance of the breast cancer stem-like cells

Oncogene, 2017-03, Vol.36 (9), p.1276-1286

2017

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Conjugation of SUMO to p85 leads to a novel mechanism of PI3K regulation

Oncogene, 2016-06, Vol.35 (22), p.2873-2880

2016

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PER1 suppresses glycolysis and cell proliferation in oral squamous cell carcinoma via the PER1/RACK1/PI3K signaling complex

Cell death & disease, 2021-03, Vol.12 (3), p.276-276, Article 276

2021

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EGFR-PI3K-PDK1 pathway regulates YAP signaling in hepatocellular carcinoma: the mechanism and its implications in targeted therapy

Cell death & disease, 2018-02, Vol.9 (3), p.269-12, Article 269

2018

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Effects of PI3K inhibitor NVP-BKM120 on overcoming drug resistance and eliminating cancer stem cells in human breast cancer cells

Cell death & disease, 2015-12, Vol.6 (12), p.e2020-e2020

2015

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Non-catalytic role of phosphoinositide 3-kinase in mesenchymal cell migration through non-canonical induction of p85β/AP2-mediated endocytosis

Phosphoinositide 3-kinase p110δ promotes lumen formation through the enhancement of apico-basal polarity and basal membrane organization

A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria

Characterisation of a cyclic peptide that binds to the RAS binding domain of phosphoinositide 3-kinase p110α

At a crossroads: how to translate the roles of PI3K in oncogenic and metabolic signalling into improvements in cancer therapy

The role of PI3Kγ in the immune system: new insights and translational implications

Phosphatidylinositol 3-kinase p110δ drives intestinal fibrosis in SHIP deficiency

Pan-cancer analysis on the role of PIK3R1 and PIK3R2 in human tumors

The interleukin-33-mediated inhibition of expression of two key genes implicated in atherosclerosis in human macrophages requires MAP kinase, phosphoinositide 3-kinase and nuclear factor-κB signaling pathways

Deficiency in class III PI3-kinase confers postnatal lethality with IBD-like features in zebrafish

TLR9 and beclin 1 crosstalk regulates muscle AMPK activation in exercise

The present and future of PI3K inhibitors for cancer therapy

Identification of the Binding Sites on Rab5 and p110beta Phosphatidylinositol 3-kinase

Autophagy restricts proliferation driven by oncogenic phosphatidylinositol 3-kinase in three-dimensional culture

A conserved mechanism of TOR-dependent RCK-mediated mRNA degradation regulates autophagy

A class of highly selective inhibitors bind to an active state of PI3Kγ

Development and characterisation of a panel of phosphatidylinositide 3-kinase - mammalian target of rapamycin inhibitor resistant lung cancer cell lines

p85α recruitment by the CD300f phosphatidylserine receptor mediates apoptotic cell clearance required for autoimmunity suppression

A novel lncRNA LNC_000052 leads to the dysfunction of osteoporotic BMSCs via the miR-96-5p-PIK3R1 axis

PI3Kβ controls immune evasion in PTEN-deficient breast tumours

Addiction to the IGF2-ID1-IGF2 circuit for maintenance of the breast cancer stem-like cells

Conjugation of SUMO to p85 leads to a novel mechanism of PI3K regulation

PER1 suppresses glycolysis and cell proliferation in oral squamous cell carcinoma via the PER1/RACK1/PI3K signaling complex

EGFR-PI3K-PDK1 pathway regulates YAP signaling in hepatocellular carcinoma: the mechanism and its implications in targeted therapy

Effects of PI3K inhibitor NVP-BKM120 on overcoming drug resistance and eliminating cancer stem cells in human breast cancer cells

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