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Establishment of auditory discrimination and detection of tinnitus induced by salicylic acid and intense tone exposure in the rat

Brain research, 2013-05, Vol.1510, p.48-62

2013

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A behavioural operant discrimination model for assessment and pharmacological manipulation of visual function in rats

Brain research, 2010-03, Vol.1321, p.78-87

2010

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AZD9272 and AZD2066: selective and highly central nervous system penetrant mGluR5 antagonists characterized by their discriminative effects

The Journal of pharmacology and experimental therapeutics, 2014-08, Vol.350 (2), p.212-222

2014

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Drug discrimination: A versatile tool for characterization of CNS safety pharmacology and potential for drug abuse

Journal of pharmacological and toxicological methods, 2016-09, Vol.81, p.295-305

Swedberg, Michael D.B.

2016

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mGluR5 antagonist-induced psychoactive properties: MTEP drug discrimination, a pharmacologically selective non-NMDA effect with apparent lack of reinforcing properties

The Journal of pharmacology and experimental therapeutics, 2014-04, Vol.349 (1), p.155-164

2014

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Prediction and modeling of effects on the QTc interval for clinical safety margin assessment, based on single-ascending-dose study data with AZD3839

The Journal of pharmacology and experimental therapeutics, 2014-08, Vol.350 (2), p.469-478

2014

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Synthesis of Novel GABA Uptake Inhibitors. 3. Diaryloxime and Diarylvinyl Ether Derivatives of Nipecotic Acid and Guvacine as Anticonvulsant Agents

Journal of medicinal chemistry, 1999-09, Vol.42 (18), p.3447-3462

1999

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Synthesis of Novel GABA Uptake Inhibitors. 4. Bioisosteric Transformation and Successive Optimization of Known GABA Uptake Inhibitors Leading to a Series of Potent Anticonvulsant Drug Candidates

Journal of medicinal chemistry, 1999-10, Vol.42 (21), p.4281-4291

1999

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Synthesis of Novel γ-Aminobutyric Acid (GABA) Uptake Inhibitors. 5. Preparation and Structure−Activity Studies of Tricyclic Analogues of Known GABA Uptake Inhibitors

Journal of medicinal chemistry, 2001-06, Vol.44 (13), p.2152-2163

2001

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Muscarinic Agonists with Antipsychotic-like Activity: Structure−Activity Relationships of 1,2,5-Thiadiazole Analogues with Functional Dopamine Antagonist Activity

Journal of medicinal chemistry, 1998-10, Vol.41 (22), p.4378-4384

1998

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1,2,5-Thiadiazole Analogues of Aceclidine as Potent m1 Muscarinic Agonists

Journal of medicinal chemistry, 1998-01, Vol.41 (3), p.379-392

1998

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Effects of infusion rate of intravenously administered morphine on physiological, psychomotor, and self-reported measures in humans

The Journal of pharmacology and experimental therapeutics, 2001-12, Vol.299 (3), p.1056

2001

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Muscarinic Analgesics with Potent and Selective Effects on the Gastrointestinal Tract: Potential Application for the Treatment of Irritable Bowel Syndrome

Journal of medicinal chemistry, 1997-02, Vol.40 (4), p.538-546

1997

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Conformationally Constrained Analogues of the Muscarinic Agonist 3-(4-(Methylthio)-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methylpyridine. Synthesis, Receptor Affinity, and Antinociceptive Activity

Journal of medicinal chemistry, 1998-01, Vol.41 (1), p.109-116

1998

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Drug discrimination: A model for detection of psychoactive effects

Journal of pharmacological and toxicological methods, 2011-07, Vol.64 (1), p.e23-e23

Swedberg, Michael D.B.

2011

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Assessment of abuse liability using rat self-administration: Methodological considerations

Journal of pharmacological and toxicological methods, 2011-07, Vol.64 (1), p.e23-e24

2011

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Synthesis of novel GABA uptake inhibitors. Part 6 : Preparation and evaluation of N-Ω asymmetrically substituted nipecotic acid derivatives

Bioorganic & medicinal chemistry, 2001-11, Vol.9 (11), p.2773-2785

2001

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Butylthio[2.2.2] (NNC 11-1053/LY297802): an orally active muscarinic agonist analgesic

The Journal of pharmacology and experimental therapeutics, 1997-05, Vol.281 (2), p.876

1997

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Pharmacology of butylthio[2.2.2] (LY297802/NNC11-1053): a novel analgesic with mixed muscarinic receptor agonist and antagonist activity

The Journal of pharmacology and experimental therapeutics, 1997-05, Vol.281 (2), p.884

1997

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NNC 19-1228 and NNC 22-0031, novel neuroleptics with a mesolimbic-selective behavioral profile

Psychopharmacologia, 1997-01, Vol.129 (2), p.168-178

1997

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M1 receptor agonist activity is not a requirement for muscarinic antinociception

The Journal of pharmacology and experimental therapeutics, 1997-05, Vol.281 (2), p.868

1997

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1,2,5-Thiadiazole Analogues of Aceclidine as Potent m 1 Muscarinic Agonists

Journal of medicinal chemistry, 1998-01, Vol.41 (3), p.379-392

1998

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Drug discrimination procedures: roles of relative stimulus control in two-drug cases

Psychopharmacologia, 1985, Vol.86 (4), p.444-451

1985

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Compound drug discrimination learning

Drug development research, 1989, Vol.16 (2-4), p.111-122

1989

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Ivabradine and outcomes in chronic heart failure (SHIFT): a randomised placebo-controlled study

The Lancet (British edition), 2010-09, Vol.376 (9744), p.875-885

2010

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Establishment of auditory discrimination and detection of tinnitus induced by salicylic acid and intense tone exposure in the rat

A behavioural operant discrimination model for assessment and pharmacological manipulation of visual function in rats

AZD9272 and AZD2066: selective and highly central nervous system penetrant mGluR5 antagonists characterized by their discriminative effects

Drug discrimination: A versatile tool for characterization of CNS safety pharmacology and potential for drug abuse

mGluR5 antagonist-induced psychoactive properties: MTEP drug discrimination, a pharmacologically selective non-NMDA effect with apparent lack of reinforcing properties

Prediction and modeling of effects on the QTc interval for clinical safety margin assessment, based on single-ascending-dose study data with AZD3839

Synthesis of Novel GABA Uptake Inhibitors. 3. Diaryloxime and Diarylvinyl Ether Derivatives of Nipecotic Acid and Guvacine as Anticonvulsant Agents

Synthesis of Novel GABA Uptake Inhibitors. 4. Bioisosteric Transformation and Successive Optimization of Known GABA Uptake Inhibitors Leading to a Series of Potent Anticonvulsant Drug Candidates

Synthesis of Novel γ-Aminobutyric Acid (GABA) Uptake Inhibitors. 5. Preparation and Structure−Activity Studies of Tricyclic Analogues of Known GABA Uptake Inhibitors

Muscarinic Agonists with Antipsychotic-like Activity: Structure−Activity Relationships of 1,2,5-Thiadiazole Analogues with Functional Dopamine Antagonist Activity

1,2,5-Thiadiazole Analogues of Aceclidine as Potent m1 Muscarinic Agonists

Effects of infusion rate of intravenously administered morphine on physiological, psychomotor, and self-reported measures in humans

Muscarinic Analgesics with Potent and Selective Effects on the Gastrointestinal Tract: Potential Application for the Treatment of Irritable Bowel Syndrome

Conformationally Constrained Analogues of the Muscarinic Agonist 3-(4-(Methylthio)-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methylpyridine. Synthesis, Receptor Affinity, and Antinociceptive Activity

Drug discrimination: A model for detection of psychoactive effects

Assessment of abuse liability using rat self-administration: Methodological considerations

Synthesis of novel GABA uptake inhibitors. Part 6 : Preparation and evaluation of N-Ω asymmetrically substituted nipecotic acid derivatives

Butylthio[2.2.2] (NNC 11-1053/LY297802): an orally active muscarinic agonist analgesic

Pharmacology of butylthio[2.2.2] (LY297802/NNC11-1053): a novel analgesic with mixed muscarinic receptor agonist and antagonist activity

NNC 19-1228 and NNC 22-0031, novel neuroleptics with a mesolimbic-selective behavioral profile

M1 receptor agonist activity is not a requirement for muscarinic antinociception

1,2,5-Thiadiazole Analogues of Aceclidine as Potent m 1 Muscarinic Agonists

Drug discrimination procedures: roles of relative stimulus control in two-drug cases

Compound drug discrimination learning

Ivabradine and outcomes in chronic heart failure (SHIFT): a randomised placebo-controlled study

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