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New miconazole-based azoles derived from eugenol show activity against Candida spp. and Cryptococcus gattii by inhibiting the fungal ergosterol biosynthesis

European journal of medicinal chemistry, 2023-08, Vol.256, p.115436-115436, Article 115436

2023

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Heat shock protein 90 (Hsp90)/Histone deacetylase (HDAC) dual inhibitors for the treatment of azoles-resistant Candida albicans

European journal of medicinal chemistry, 2022-01, Vol.227, p.113961-113961, Article 113961

2022

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Design, synthesis, and structure–activity relationship studies of novel thienopyrrolidone derivatives with strong antifungal activity against Aspergillus fumigates

European journal of medicinal chemistry, 2015-09, Vol.102, p.471-476

2015

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Synthesis and biological activities of novel amine-derived bis-azoles as potential antibacterial and antifungal agents

European journal of medicinal chemistry, 2010-09, Vol.45 (9), p.4388-4398

2010

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Imidazolylchromanones containing non-benzylic oxime ethers: Synthesis and molecular modeling study of new azole antifungals selective against Cryptococcus gattii

European journal of medicinal chemistry, 2014-04, Vol.76, p.264-273

2014

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Synthesis and antimicrobial activity of amido linked pyrrolyl and pyrazolyl-oxazoles, thiazoles and imidazoles

European journal of medicinal chemistry, 2011-11, Vol.46 (11), p.5317-5326

2011

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New (arylalkyl)azole derivatives showing anticonvulsant effects could have VGSC and/or GABA A R affinity according to molecular modeling studies

European journal of medicinal chemistry, 2016-11, Vol.124, p.407-416

2016

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Antifungal activity, mode of action variability, and subcellular distribution of coumarin-based antifungal azoles

European journal of medicinal chemistry, 2019-10, Vol.179, p.779-790

2019

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Design, synthesis, and evaluation of antitumor activity in Pseudolaric acid B Azole derivatives: Novel and potent angiogenesis inhibitor via regulation of the PI3K/AKT and MAPK mediated HIF-1/VEGF signaling pathway

European journal of medicinal chemistry, 2024-11, Vol.278, p.116813, Article 116813

2024

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Synthesis and evaluation of new furanyl and thiophenyl azoles as antileishmanial agents

European journal of medicinal chemistry, 2011-05, Vol.46 (5), p.1694-1700

2011

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Synthesis, characterisation and biological activity of novel 4-thiazolidinones, 1,3,4-oxadiazoles and some related compounds

European journal of medicinal chemistry, 2002-03, Vol.37 (3), p.197-206

2002

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New azoles with potent antifungal activity: Design, synthesis and molecular docking

European journal of medicinal chemistry, 2009-10, Vol.44 (10), p.4218-4226

2009

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Thiadiazole-, selenadiazole- and triazole-fused anthraquinones as G-quadruplex targeting anticancer compounds

European journal of medicinal chemistry, 2024-03, Vol.268, p.116222-116222, Article 116222

2024

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Design and synthesis of antifungal benzoheterocyclic derivatives by scaffold hopping

European journal of medicinal chemistry, 2011-05, Vol.46 (5), p.1706-1712

2011

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Synthesis and evaluation of new difluoromethyl azoles as antileishmanial agents

European journal of medicinal chemistry, 2007-11, Vol.42 (11), p.1388-1395

2007

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Current advances of triazole alcohols derived from fluconazole: Design, in vitro and in silico studies

European journal of medicinal chemistry, 2019-05, Vol.170, p.173-194

2019

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The synthesis and activities of novel mononuclear or dinuclear cyclen complexes bearing azole pendants as antibacterial and antifungal agents

European journal of medicinal chemistry, 2014-09, Vol.84, p.677-686

2014

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Synthesis and in vitro anti-bacterial evaluation of tetracyclic-ortho-fused 4H-naphtho[1',2'-5,6]pyrano [3,4-d](1,2,3)selenadiazole and its derivatives

European journal of medicinal chemistry, 2008-11, Vol.43 (11), p.2615-2617

2008

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A facile synthesis of carbocycle-fused mono and bis-1,2,3-selenadiazoles and their antimicrobial and antimycobacterial studies

European journal of medicinal chemistry, 2011-11, Vol.46 (11), p.5465-5472

2011

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New azole antifungals with a fused triazinone scaffold

European journal of medicinal chemistry, 2020-03, Vol.189, p.112082-112082, Article 112082

2020

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Synthesis of tetrazole derivatives bearing pyrrolidine scaffold and evaluation of their antifungal activity against Candida albicans

European journal of medicinal chemistry, 2019-02, Vol.164, p.106-120

2019

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Design, synthesis, and structure-activity relationship studies of l-amino alcohol derivatives as broad-spectrum antifungal agents

European journal of medicinal chemistry, 2019-09, Vol.177, p.374-385

2019

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Discovery of in vitro antitubercular agents through in silico ligand-based approaches

European journal of medicinal chemistry, 2016-10, Vol.121, p.169-180

2016

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Synthesis and anti-tuberculosis activity of N-aryl- C-nitroazoles

European journal of medicinal chemistry, 2004-10, Vol.39 (10), p.849-853

2004

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Synthesis and antimicrobial activity of pyrimidinyl 1,3,4-oxadiazoles, 1,3,4-thiadiazoles and 1,2,4-triazoles

European journal of medicinal chemistry, 2018-02, Vol.145, p.1-10

2018

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New miconazole-based azoles derived from eugenol show activity against Candida spp. and Cryptococcus gattii by inhibiting the fungal ergosterol biosynthesis

Heat shock protein 90 (Hsp90)/Histone deacetylase (HDAC) dual inhibitors for the treatment of azoles-resistant Candida albicans

Design, synthesis, and structure–activity relationship studies of novel thienopyrrolidone derivatives with strong antifungal activity against Aspergillus fumigates

Synthesis and biological activities of novel amine-derived bis-azoles as potential antibacterial and antifungal agents

Imidazolylchromanones containing non-benzylic oxime ethers: Synthesis and molecular modeling study of new azole antifungals selective against Cryptococcus gattii

Synthesis and antimicrobial activity of amido linked pyrrolyl and pyrazolyl-oxazoles, thiazoles and imidazoles

New (arylalkyl)azole derivatives showing anticonvulsant effects could have VGSC and/or GABA A R affinity according to molecular modeling studies

Antifungal activity, mode of action variability, and subcellular distribution of coumarin-based antifungal azoles

Design, synthesis, and evaluation of antitumor activity in Pseudolaric acid B Azole derivatives: Novel and potent angiogenesis inhibitor via regulation of the PI3K/AKT and MAPK mediated HIF-1/VEGF signaling pathway

Synthesis and evaluation of new furanyl and thiophenyl azoles as antileishmanial agents

Synthesis, characterisation and biological activity of novel 4-thiazolidinones, 1,3,4-oxadiazoles and some related compounds

New azoles with potent antifungal activity: Design, synthesis and molecular docking

Thiadiazole-, selenadiazole- and triazole-fused anthraquinones as G-quadruplex targeting anticancer compounds

Design and synthesis of antifungal benzoheterocyclic derivatives by scaffold hopping

Synthesis and evaluation of new difluoromethyl azoles as antileishmanial agents

Current advances of triazole alcohols derived from fluconazole: Design, in vitro and in silico studies

The synthesis and activities of novel mononuclear or dinuclear cyclen complexes bearing azole pendants as antibacterial and antifungal agents

Synthesis and in vitro anti-bacterial evaluation of tetracyclic-ortho-fused 4H-naphtho[1',2'-5,6]pyrano [3,4-d](1,2,3)selenadiazole and its derivatives

A facile synthesis of carbocycle-fused mono and bis-1,2,3-selenadiazoles and their antimicrobial and antimycobacterial studies

New azole antifungals with a fused triazinone scaffold

Synthesis of tetrazole derivatives bearing pyrrolidine scaffold and evaluation of their antifungal activity against Candida albicans

Design, synthesis, and structure-activity relationship studies of l-amino alcohol derivatives as broad-spectrum antifungal agents

Discovery of in vitro antitubercular agents through in silico ligand-based approaches

Synthesis and anti-tuberculosis activity of N-aryl- C-nitroazoles

Synthesis and antimicrobial activity of pyrimidinyl 1,3,4-oxadiazoles, 1,3,4-thiadiazoles and 1,2,4-triazoles

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