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Discovery of a Novel Potent Tetrazole Antifungal Candidate with High Selectivity and Broad Spectrum

Journal of medicinal chemistry, 2024-04, Vol.67 (8), p.6238-6252

2024

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Structure-Function Analysis of the Essential Mycobacterium tuberculosis P450 Drug Target, CYP121A1

International journal of molecular sciences, 2024-05, Vol.25 (9), p.4886

2024

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Determination of arbutin in vitro and in vivo by LC-MS/MS: Pre-clinical evaluation of natural product arbutin for its early medicinal properties

Journal of ethnopharmacology, 2024-08, Vol.330, p.118232-118232, Article 118232

2024

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Metabolic activation and cytochrome P450 inhibition of piperlonguminine mediated by CYP3A4

International journal of biological macromolecules, 2024-05, Vol.268 (Pt 2), p.131502-131502, Article 131502

2024

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CYP2J2-mediated metabolism of arachidonic acid in heart: A review of its kinetics, inhibition and role in heart rhythm control

Pharmacology & therapeutics (Oxford), 2024-06, Vol.258, p.108637-108637, Article 108637

2024

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Cytochrome P450 CYP736A12 is crucial for Trichoderma asperellum-induced alleviation of phoxim phytotoxicity and reduction of pesticide residue in tomato roots

Journal of hazardous materials, 2024-06, Vol.471, p.134299-134299, Article 134299

2024

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Phytomediated stress modulates antioxidant status, induces overexpression of CYP6M2, Hsp70, α-esterase, and suppresses the ABC transporter in Anopheles gambiae (sensu stricto) exposed to Ocimum tenuiflorum extracts

PloS one, 2024, Vol.19 (5), p.e0302677-e0302677

2024

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A secondary mechanism of action for triazole antifungals in Aspergillus fumigatus mediated by hmg1

Nature communications, 2024-04, Vol.15 (1), p.3642-3642

2024

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Role of CYP9E2 and a long non-coding RNA gene in resistance to a spinosad insecticide in the Colorado potato beetle, Leptinotarsa decemlineata

PloS one, 2024-05, Vol.19 (5), p.e0304037-e0304037

2024

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Carboxylesterase and Cytochrome P450 Confer Metabolic Resistance Simultaneously to Azoxystrobin and Some Other Fungicides in Botrytis cinerea

Journal of agricultural and food chemistry, 2024-05, Vol.72 (17), p.9680-9690

2024

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Cytochrome P450 SmCYP78A7a positively functions in eggplant response to salt stress via forming a positive feedback loop with SmWRKY11

International journal of biological macromolecules, 2024-06, Vol.269 (Pt 2), p.132139-132139, Article 132139

2024

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Lactic acid bacteria modulate the CncC pathway to enhance resistance to β-cypermethrin in the oriental fruit fly

The ISME Journal, 2024-01, Vol.18 (1)

2024

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Target-site and non-target-site resistance mechanisms confer mesosulfuron-methyl resistance in Alopecurus aequalis

Plant physiology and biochemistry, 2024-05, Vol.210, p.108597-108597, Article 108597

2024

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Metabolism-Based Nontarget-Site Mechanism Is the Main Cause of a Four-Way Resistance in Shortawn Foxtail (Alopecurus aequalis Sobol.)

Journal of agricultural and food chemistry, 2024-05, Vol.72 (21), p.12014-12028

2024

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Enhanced Herbicide Metabolism and Target Site Mutation Enabled the Multiple Resistance to Cyhalofop-butyl, Florpyrauxifen-benzyl, and Penoxsulam in Echinochloa crus-galli

Journal of agricultural and food chemistry, 2024-05, Vol.72 (20), p.11405-11414

2024

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Transcription Factors AhR and ARNT Regulate the Expression of CYP6SX1 and CYP3828A1 Involved in Insecticide Detoxification in Bradysia odoriphaga

Journal of agricultural and food chemistry, 2024-05, Vol.72 (19), p.10805-10813

2024

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The role of the cytochrome P450 superfamily in the skin

Expert reviews in molecular medicine, 2024-04, Vol.26, p.e15-e15

2024

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Molecular mechanisms of cytochrome P450-mediated detoxification of tetraniliprole, spinetoram, and emamectin benzoate in the fall armyworm, Spodoptera frugiperda (J.E. Smith)

Bulletin of entomological research, 2024-04, Vol.114 (2), p.159-171

2024

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An Asp376Glu substitution and P450s-involved metabolism endow resistance to ALS inhibitors in an Ammannia auriculata Willd. Population

Pesticide biochemistry and physiology, 2024-05, Vol.201, p.105911-105911, Article 105911

2024

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Effect of chlorpyrifos‐exposure on the expression levels of CYP genes in Daphnia magna and examination of a possibility that an up‐regulated clan 3 CYP, CYP360A8, reacts with pesticides

Environmental toxicology, 2024-06, Vol.39 (6), p.3641-3653

2024

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Knockdown of one cytochrome P450 gene CYP6DW4 increases the susceptibility of Bemisia tabaci to dimpropyridaz, a novel pyridazine pyrazolecarboxamide insecticide

Pesticide biochemistry and physiology, 2024-05, Vol.201, p.105888-105888, Article 105888

2024

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Interactions between grapefruit juice and psychotropic medications: an update of the literature and an original case series

Expert opinion on drug metabolism & toxicology, 2024-05, Vol.20 (5), p.333-345

2024

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Effects of Chemicals in Reporter Gene Bioassays with Different Metabolic Activities Compared to Baseline Toxicity

Chemical research in toxicology, 2024-05, Vol.37 (5), p.744-756

2024

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Prediction of cytochrome P450-mediated bioactivation using machine learning models and in vitro validation

Archives of toxicology, 2024-05, Vol.98 (5), p.1457-1467

2024

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Cell type-dependent response to benzo(a)pyrene exposure of human placental cell lines under normoxic, hypoxic, and pro-inflammatory conditions

Ecotoxicology and environmental safety, 2024-05, Vol.276, p.116287-116287, Article 116287

2024

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Discovery of a Novel Potent Tetrazole Antifungal Candidate with High Selectivity and Broad Spectrum

Structure-Function Analysis of the Essential Mycobacterium tuberculosis P450 Drug Target, CYP121A1

Determination of arbutin in vitro and in vivo by LC-MS/MS: Pre-clinical evaluation of natural product arbutin for its early medicinal properties

Metabolic activation and cytochrome P450 inhibition of piperlonguminine mediated by CYP3A4

CYP2J2-mediated metabolism of arachidonic acid in heart: A review of its kinetics, inhibition and role in heart rhythm control

Cytochrome P450 CYP736A12 is crucial for Trichoderma asperellum-induced alleviation of phoxim phytotoxicity and reduction of pesticide residue in tomato roots

Phytomediated stress modulates antioxidant status, induces overexpression of CYP6M2, Hsp70, α-esterase, and suppresses the ABC transporter in Anopheles gambiae (sensu stricto) exposed to Ocimum tenuiflorum extracts

A secondary mechanism of action for triazole antifungals in Aspergillus fumigatus mediated by hmg1

Role of CYP9E2 and a long non-coding RNA gene in resistance to a spinosad insecticide in the Colorado potato beetle, Leptinotarsa decemlineata

Carboxylesterase and Cytochrome P450 Confer Metabolic Resistance Simultaneously to Azoxystrobin and Some Other Fungicides in Botrytis cinerea

Cytochrome P450 SmCYP78A7a positively functions in eggplant response to salt stress via forming a positive feedback loop with SmWRKY11

Lactic acid bacteria modulate the CncC pathway to enhance resistance to β-cypermethrin in the oriental fruit fly

Target-site and non-target-site resistance mechanisms confer mesosulfuron-methyl resistance in Alopecurus aequalis

Metabolism-Based Nontarget-Site Mechanism Is the Main Cause of a Four-Way Resistance in Shortawn Foxtail (Alopecurus aequalis Sobol.)

Enhanced Herbicide Metabolism and Target Site Mutation Enabled the Multiple Resistance to Cyhalofop-butyl, Florpyrauxifen-benzyl, and Penoxsulam in Echinochloa crus-galli

Transcription Factors AhR and ARNT Regulate the Expression of CYP6SX1 and CYP3828A1 Involved in Insecticide Detoxification in Bradysia odoriphaga

The role of the cytochrome P450 superfamily in the skin

Molecular mechanisms of cytochrome P450-mediated detoxification of tetraniliprole, spinetoram, and emamectin benzoate in the fall armyworm, Spodoptera frugiperda (J.E. Smith)

An Asp376Glu substitution and P450s-involved metabolism endow resistance to ALS inhibitors in an Ammannia auriculata Willd. Population

Effect of chlorpyrifos‐exposure on the expression levels of CYP genes in Daphnia magna and examination of a possibility that an up‐regulated clan 3 CYP, CYP360A8, reacts with pesticides

Knockdown of one cytochrome P450 gene CYP6DW4 increases the susceptibility of Bemisia tabaci to dimpropyridaz, a novel pyridazine pyrazolecarboxamide insecticide

Interactions between grapefruit juice and psychotropic medications: an update of the literature and an original case series

Effects of Chemicals in Reporter Gene Bioassays with Different Metabolic Activities Compared to Baseline Toxicity

Prediction of cytochrome P450-mediated bioactivation using machine learning models and in vitro validation

Cell type-dependent response to benzo(a)pyrene exposure of human placental cell lines under normoxic, hypoxic, and pro-inflammatory conditions

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