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1,25-Dihydroxyvitamin D(3) and 9-cis-retinoids are synergistic regulators of 24-hydroxylase activity in the rat and 1, 25-dihydroxyvitamin D(3) alters retinoic acid metabolism in vivo

Archives of biochemistry and biophysics, 1999-08, Vol.368 (2), p.244

1999

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1,25-Dihydroxyvitamin D(3) downregulates the rat intestinal vitamin D(3)-25-hydroxylase CYP27A

American journal of physiology: endocrinology and metabolism, 2001-08, Vol.281 (2), p.E315-E325

2001

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1,25-Dihydroxyvitamin D3 Increases Nuclear Vitamin D3 Receptors by Blocking Ubiquitin/Proteasome-Mediated Degradation in Human Skin

Molecular endocrinology (Baltimore, Md.), 1999-10, Vol.13 (10), p.1686-1694

1999

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1,5-Biaryl pyrrole derivatives as EP1 receptor antagonists. structure-activity relationships of 6-substituted and 5,6-disubstituted benzoic acid derivatives

Bioorganic & medicinal chemistry letters, 2007-02, Vol.17 (4), p.916-920

2007

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1 alpha,25-Dihydroxyvitamin D(3) inhibits rat liver ultrastructural changes in diethylnitrosamine-initiated and phenobarbital promoted rat hepatocarcinogenesis

Journal of cellular biochemistry, 2001-03, Vol.81 (2), p.357

2001

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11,12-Epoxyeicosatrienoic Acid Attenuates Synthesis of Prostaglandin E2 in Rat Monocytes Stimulated with Lipopolysaccharide

Experimental biology and medicine (Maywood, N.J.), 2003-07, Vol.228 (7), p.786-794

2003

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12(R)-Hydroxyeicosatetraenoic acid synthesis by 3-methylcholanthrene- and clofibrate-inducible cytochrome P450 in porcine ciliary epithelium

Biochemical and biophysical research communications, 1992-08, Vol.187 (1), p.455-459

1992

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16(R)-hydroxyeicosatetraenoic acid, a novel cytochrome P450 product of arachidonic acid, suppresses activation of human polymorphonuclear leukocyte and reduces intracranial pressure in a rabbit model of thromboembolic stroke

Neurosurgery, 2000-12, Vol.47 (6), p.1410

2000

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17beta-estradiol decreases vascular tone in cerebral arteries by shifting COX-dependent vasoconstriction to vasodilation

American journal of physiology. Heart and circulatory physiology, 2003-07, Vol.285 (1), p.H241-H250

2003

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17beta-estradiol increases rat cerebrovascular prostacyclin synthesis by elevating cyclooxygenase-1 and prostacyclin synthase

Stroke (1970), 2002-02, Vol.33 (2), p.600-605

2002

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17beta-estradiol up-regulates prostacyclin production in cultured human uterine myometrial cells via augmentation of both cyclooxygenase-1 and prostacyclin synthase expression

Journal of the Society for Gynecologic Investigation, 2004-10, Vol.11 (7), p.457-464

2004

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17α-Alkynyl 3α, 17β-androstanediol non-clinical and clinical pharmacology, pharmacokinetics and metabolism

Investigational new drugs, 2012-02, Vol.30 (1), p.59-78

2012

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17β-Estradiol in the systemic circulation derives mainly from the parietal cells in cholestatic female rats

Journal of endocrinological investigation, 2016-04, Vol.39 (4), p.389-400

2016

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19-nor-1,25(OH)2D2 (a novel, noncalcemic vitamin D analogue), combined with arsenic trioxide, has potent antitumor activity against myeloid leukemia

Cancer research (Chicago, Ill.), 2005-03, Vol.65 (6), p.2488-2497

2005

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The 1984 Bernard B. Brodie Award lecture. From morphine to interferon: an odyssey of drug metabolism

Drug metabolism and disposition, 1986-01, Vol.14 (1), p.1

Mannering, G J

1986

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1alpha, 25-Dihydroxyvitamin D3 suppresses the effect of streptozotocin-induced diabetes during chemical rat liver carcinogenesis

Cell biology international, 2001, Vol.25 (3), p.227

2001

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1alpha,25-(OH)2D3 regulates 25-hydroxyvitamin D3 24R-hydroxylase activity in growth zone costochondral growth plate chondrocytes via protein kinase C

Calcified tissue international, 2001-12, Vol.69 (6), p.365-372

2001

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2.1 Å Crystal Structure of Human PXR in Complex with the St. John's Wort Compound Hyperforin

Biochemistry (Easton), 2003-02, Vol.42 (6), p.1430-1438

2003

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2,2',3',4,4'5,5'-Hepatachlorobiphenyl (PCB 180)--on its toxicokinetics, biotransformation and porphyrinogenic action in female rats

Archives of toxicology, 1993, Vol.67 (9), p.651

1993

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2,2′,4,4′,5,5′- and 3,3′,4,4′,5,5′-Hexachlorobiphenyl Alteration of Uterine Progesterone and Estrogen Receptors Coincides with Embryotoxicity in Mink (Mustela vison)

Toxicology and applied pharmacology, 1994-07, Vol.127 (1), p.9-18

1994

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2,2-Dimethyl-5- t-butyl-1,3-benzodioxole: An unusual inducer of microsomal enzymes

Biochemical pharmacology, 1984-12, Vol.33 (24), p.3941-3946

1984

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2,3,7,8-Tetrachlorodibenzo-p-dioxin causes an extensive alteration of 17 beta-estradiol metabolism in MCF-7 breast tumor cells

Proceedings of the National Academy of Sciences - PNAS, 1990-09, Vol.87 (17), p.6917-6921

1990

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2,3,7,8-Tetrachlorodibenzo-p-dioxin-dependent regulation of transforming growth factors-alpha and -beta 2 expression in a human keratinocyte cell line involves both transcriptional and post-transcriptional control

The Journal of biological chemistry, 1992-12, Vol.267 (34), p.24591-24595

1992

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2,3,7,8-Tetrachlorodibenzo-p-dioxin-inducible aryl hydrocarbon receptor-mediated change in CYP1A1 chromatin structure occurs independently of transcription

Molecular and Cellular Biology, 1989-12, Vol.9 (12), p.5733-5737

1989

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2,3,7,8-tetrachlorodibenzo- p-dioxin-mediated depression of rat testicular heme synthesis and microsomal cytochrome P-450

Biochemical pharmacology, 1982-11, Vol.31 (22), p.3663-3666

1982

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1,25-Dihydroxyvitamin D(3) and 9-cis-retinoids are synergistic regulators of 24-hydroxylase activity in the rat and 1, 25-dihydroxyvitamin D(3) alters retinoic acid metabolism in vivo

1,25-Dihydroxyvitamin D(3) downregulates the rat intestinal vitamin D(3)-25-hydroxylase CYP27A

1,25-Dihydroxyvitamin D3 Increases Nuclear Vitamin D3 Receptors by Blocking Ubiquitin/Proteasome-Mediated Degradation in Human Skin

1,5-Biaryl pyrrole derivatives as EP1 receptor antagonists. structure-activity relationships of 6-substituted and 5,6-disubstituted benzoic acid derivatives

1 alpha,25-Dihydroxyvitamin D(3) inhibits rat liver ultrastructural changes in diethylnitrosamine-initiated and phenobarbital promoted rat hepatocarcinogenesis

11,12-Epoxyeicosatrienoic Acid Attenuates Synthesis of Prostaglandin E2 in Rat Monocytes Stimulated with Lipopolysaccharide

12(R)-Hydroxyeicosatetraenoic acid synthesis by 3-methylcholanthrene- and clofibrate-inducible cytochrome P450 in porcine ciliary epithelium

16(R)-hydroxyeicosatetraenoic acid, a novel cytochrome P450 product of arachidonic acid, suppresses activation of human polymorphonuclear leukocyte and reduces intracranial pressure in a rabbit model of thromboembolic stroke

17beta-estradiol decreases vascular tone in cerebral arteries by shifting COX-dependent vasoconstriction to vasodilation

17beta-estradiol increases rat cerebrovascular prostacyclin synthesis by elevating cyclooxygenase-1 and prostacyclin synthase

17beta-estradiol up-regulates prostacyclin production in cultured human uterine myometrial cells via augmentation of both cyclooxygenase-1 and prostacyclin synthase expression

17α-Alkynyl 3α, 17β-androstanediol non-clinical and clinical pharmacology, pharmacokinetics and metabolism

17β-Estradiol in the systemic circulation derives mainly from the parietal cells in cholestatic female rats

19-nor-1,25(OH)2D2 (a novel, noncalcemic vitamin D analogue), combined with arsenic trioxide, has potent antitumor activity against myeloid leukemia

The 1984 Bernard B. Brodie Award lecture. From morphine to interferon: an odyssey of drug metabolism

1alpha, 25-Dihydroxyvitamin D3 suppresses the effect of streptozotocin-induced diabetes during chemical rat liver carcinogenesis

1alpha,25-(OH)2D3 regulates 25-hydroxyvitamin D3 24R-hydroxylase activity in growth zone costochondral growth plate chondrocytes via protein kinase C

2.1 Å Crystal Structure of Human PXR in Complex with the St. John's Wort Compound Hyperforin

2,2',3',4,4'5,5'-Hepatachlorobiphenyl (PCB 180)--on its toxicokinetics, biotransformation and porphyrinogenic action in female rats

2,2′,4,4′,5,5′- and 3,3′,4,4′,5,5′-Hexachlorobiphenyl Alteration of Uterine Progesterone and Estrogen Receptors Coincides with Embryotoxicity in Mink (Mustela vison)

2,2-Dimethyl-5- t-butyl-1,3-benzodioxole: An unusual inducer of microsomal enzymes

2,3,7,8-Tetrachlorodibenzo-p-dioxin causes an extensive alteration of 17 beta-estradiol metabolism in MCF-7 breast tumor cells

2,3,7,8-Tetrachlorodibenzo-p-dioxin-dependent regulation of transforming growth factors-alpha and -beta 2 expression in a human keratinocyte cell line involves both transcriptional and post-transcriptional control

2,3,7,8-Tetrachlorodibenzo-p-dioxin-inducible aryl hydrocarbon receptor-mediated change in CYP1A1 chromatin structure occurs independently of transcription

2,3,7,8-tetrachlorodibenzo- p-dioxin-mediated depression of rat testicular heme synthesis and microsomal cytochrome P-450

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