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Flunitrazepam metabolism by cytochrome P450S 2C19 and 3A4
Drug metabolism and disposition, 2001-04, Vol.29 (4 Pt 1), p.460
2001
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Effect of the adrenal 11-beta-hydroxylase inhibitor metyrapone on human hepatic cytochrome P-450 expression: induction of cytochrome P-450 3A4
Drug metabolism and disposition, 2000-01, Vol.28 (1), p.96
2000
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Microsomal codeine N-demethylation: cosegregation with cytochrome P4503A4 activity
Drug metabolism and disposition, 1996-07, Vol.24 (7), p.761
1996
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Cannabinoid Metabolites as Inhibitors of Major Hepatic CYP450 Enzymes, with Implications for Cannabis-Drug Interactions
Drug metabolism and disposition, 2021-12, Vol.49 (12), p.1070-1080
2021
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Silybin is metabolized by cytochrome P450 2C8 in vitro
Drug metabolism and disposition, 2007-11, Vol.35 (11), p.2035-2039
2007
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Cytochrome b 5 Binds Tightly to Several Human Cytochrome P450 Enzymes
Drug metabolism and disposition, 2021-10, Vol.49 (10), p.902-909
2021
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Gene-specific effects of inflammatory cytokines on cytochrome P450 2C, 2B6 and 3A4 mRNA levels in human hepatocytes
Drug metabolism and disposition, 2007-09, Vol.35 (9), p.1687-1693
2007
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Gemfibrozil is a potent inhibitor of human cytochrome P450 2C9
Drug metabolism and disposition, 2001-11, Vol.29 (11), p.1359
2001
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Metabolism in vivo and in vitro of the refrigerant substitute 1,1,1,2-tetrafluoro-2-chloroethane
Drug metabolism and disposition, 1991-09, Vol.19 (5), p.1004
1991
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The Reliability of Estimating Ki Values for Direct, Reversible Inhibition of Cytochrome P450 Enzymes from Corresponding IC50 Values: A Retrospective Analysis of 343 Experiments
Drug metabolism and disposition, 2015-11, Vol.43 (11), p.1744-1750
2015
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Epigenetic Mechanisms Contribute to Intraindividual Variations of Drug Metabolism Mediated by Cytochrome P450 Enzymes
Drug metabolism and disposition, 2023-06, Vol.51 (6), p.672-684
2023
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Oleuropein-Induced Acceleration of Cytochrome P450-Catalyzed Drug Metabolism: Central Role for Nuclear Receptor Peroxisome Proliferator-Activated Receptor α
Drug metabolism and disposition, 2021-09, Vol.49 (9), p.833-843
2021
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Novel single nucleotide polymorphisms in the promoter and intron 1 of human pregnane X receptor/NR1I2 and their association with CYP3A4 expression
Drug metabolism and disposition, 2008-01, Vol.36 (1), p.169-181
2008
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Validation of bupropion hydroxylation as a selective marker of human cytochrome P450 2B6 catalytic activity
Drug metabolism and disposition, 2000-10, Vol.28 (10), p.1222
2000
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Use of isolated hepatocyte preparations for cytochrome P450 inhibition studies: comparison with microsomes for Ki determination
Drug metabolism and disposition, 2007-11, Vol.35 (11), p.2119
2007
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A comparison of 2-phenyl-2-(1-piperidinyl)propane (ppp), 1,1',1''-phosphinothioylidynetrisaziridine (thioTEPA), clopidogrel, and ticlopidine as selective inactivators of human cytochrome P450 2B6
Drug metabolism and disposition, 2007-11, Vol.35 (11), p.2053-2059
2007
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Alterations of Cytochrome P450-Mediated Drug Metabolism during Liver Repair and Regeneration after Acetaminophen-Induced Liver Injury in Mice
Drug metabolism and disposition, 2022-05, Vol.50 (5), p.694-703
2022
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Serotonin Receptors of 5-HT 2 Type in the Hypothalamic Arcuate Nuclei Positively Regulate Liver Cytochrome P450 via Stimulation of the Growth Hormone-Releasing Hormone/Growth Hormone Hormonal Pathway
Drug metabolism and disposition, 2019-02, Vol.47 (2), p.80-85
2019
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Cytochrome P450 3A-dependent metabolism of a potent and selective gamma-aminobutyric acid Aalpha2/3 receptor agonist in vitro: involvement of cytochrome P450 3A5 displaying biphasic kinetics
Drug metabolism and disposition, 2007-08, Vol.35 (8), p.1301
2007
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Effect of commonly used organic solvents on the kinetics of cytochrome P450 2B6- and 2C8-dependent activity in human liver microsomes
Drug metabolism and disposition, 2007-11, Vol.35 (11), p.1990-1995
2007
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Role of Adaptor Protein Toll-Like Interleukin Domain Containing Adaptor Inducing Interferon β in Toll-Like Receptor 3- and 4-Mediated Regulation of Hepatic Drug Metabolizing Enzyme and Transporter Genes
Drug metabolism and disposition, 2016-01, Vol.44 (1), p.61-67
2016
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Further assessment of 17alpha-ethinyl estradiol as an inhibitor of different human cytochrome P450 forms in vitro
Drug metabolism and disposition, 2009-08, Vol.37 (8), p.1667
2009
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Cytochrome P-450 3A and 2D6 catalyze ortho hydroxylation of 4-hydroxytamoxifen and 3-hydroxytamoxifen (droloxifene) yielding tamoxifen catechol: involvement of catechols in covalent binding to hepatic proteins
Drug metabolism and disposition, 1999-06, Vol.27 (6), p.681
1999
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Modulation of human cytochrome P450 1B1 expression by 2,4,3',5'-tetramethoxystilbene
Drug metabolism and disposition, 2005-12, Vol.33 (12), p.1771
2005
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Warfarin-fluconazole. I. Inhibition of the human cytochrome P450-dependent metabolism of warfarin by fluconazole: in vitro studies
Drug metabolism and disposition, 1996-04, Vol.24 (4), p.414
1996
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