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Role of mitochondrial dysfunction and altered autophagy in cardiovascular aging and disease: from mechanisms to therapeutics

American journal of physiology. Heart and circulatory physiology, 2013-08, Vol.305 (4), p.H459-H476

2013

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The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging

Molecular cell, 2019-02, Vol.73 (4), p.775-787.e10

2019

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Protective Effects of α-Tocopherol, γ-Tocopherol and Oleic Acid, Three Compounds of Olive Oils, and No Effect of Trolox, on 7-Ketocholesterol-Induced Mitochondrial and Peroxisomal Dysfunction in Microglial BV-2 Cells

International journal of molecular sciences, 2016-11, Vol.17 (12), p.1973

2016

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Propofol Related Infusion Syndrome: Ultrastructural Evidence for a Mitochondrial Disorder

Critical care medicine, 2018-01, Vol.46 (1), p.e91-e94

2018

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Evidence for association of mitochondrial metabolism alteration with lipid accumulation in aging rats

Experimental gerontology, 2014-08, Vol.56, p.3-12

2014

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Neonatal multiorgan failure due to ACAD9 mutation and complex I deficiency with mitochondrial hyperplasia in liver, cardiac myocytes, skeletal muscle, and renal tubules

Human pathology, 2016-03, Vol.49, p.27-32

2016

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Idebenone ameliorates statin-induced myotoxicity in atherosclerotic ApoE−/− mice by reducing oxidative stress and improving mitochondrial function

Biochimica et biophysica acta. Molecular basis of disease, 2024-06, Vol.1870 (5), p.167157-167157, Article 167157

2024

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Mitochondrial remodeling underlying age-induced skeletal muscle wasting: let’s talk about sex

Free radical biology & medicine, 2024-06, Vol.218, p.68-81

2024

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Preserving mitochondria to treat hypertrophic cardiomyopathy: From rare mitochondrial DNA mutation to heart failure therapy?

The Journal of clinical investigation, 2023-07, Vol.133 (14)

Diwan, Abhinav

2023

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A stagewise response to mitochondrial dysfunction in mitochondrial DNA maintenance disorders

Biochimica et biophysica acta. Molecular basis of disease, 2024-06, Vol.1870 (5), p.167131-167131, Article 167131

2024

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Iron deficiency‐induced loss of skeletal muscle mitochondrial proteins and respiratory capacity; the role of mitophagy and secretion of mitochondria‐containing vesicles

The FASEB journal, 2020-05, Vol.34 (5), p.6703-6717

2020

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Mitochondrial Dysfunction in Heart Failure With Preserved Ejection Fraction

Circulation (New York, N.Y.), 2019-03, Vol.139 (11), p.1435-1450

2019

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Current Perspectives of Mitochondria in Sepsis-Induced Cardiomyopathy

International journal of molecular sciences, 2024-05, Vol.25 (9), p.4710

2024

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Aberrant expression of thyroidal hormone receptor α exasperating mitochondrial dysfunction induced sarcopenia in aged mice

Aging (Albany, NY.), 2024-04, Vol.16 (8), p.7141

2024

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In the eye of the storm: mitochondrial damage during heart and brain ischaemia

The FEBS journal, 2013-10, Vol.280 (20), p.4999-5014

2013

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Mitochondrial toxicity assessment in industry - a decade of technology development and insight

Expert opinion on drug metabolism & toxicology, 2014-08, Vol.10 (8), p.1061-1067

2014

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Mitochondrial Potassium Channels as Pharmacological Target for Cardioprotective Drugs

Medicinal research reviews, 2015-05, Vol.35 (3), p.520-553

2015

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Brain aging, Alzheimer's disease, and mitochondria

Biochimica et biophysica acta, 2011-12, Vol.1812 (12), p.1630-1639

Swerdlow, Russell H.

2011

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Mitophagy reporter mouse analysis reveals increased mitophagy activity in disuse‐induced muscle atrophy

Journal of cellular physiology, 2021-11, Vol.236 (11), p.7612-7624

2021

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Inhibition of the mPTP and Lipid Peroxidation Is Additively Protective Against I/R Injury

Circulation research, 2024-05, Vol.134 (10), p.1292

2024

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2-APQC, a small-molecule activator of Sirtuin-3 (SIRT3), alleviates myocardial hypertrophy and fibrosis by regulating mitochondrial homeostasis

Signal transduction and targeted therapy, 2024-05, Vol.9 (1), p.133-133

2024

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Mono- and double-mutant mouse models of Parkinson's disease display severe mitochondrial damage

Human molecular genetics, 2007-10, Vol.16 (20), p.2377-2393

2007

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CMT2Q-causing mutation in the Dhtkd1 gene lead to sensory defects, mitochondrial accumulation and altered metabolism in a knock-in mouse model

Acta neuropathologica communications, 2020-03, Vol.8 (1), p.32-32, Article 32

2020

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Calcium-induced generation of reactive oxygen species in brain mitochondria is mediated by permeability transition

Free radical biology & medicine, 2008-08, Vol.45 (3), p.284-294

2008

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Mitochondrial ROS in myocardial ischemia reperfusion and remodeling

Biochimica et biophysica acta. Molecular basis of disease, 2020-07, Vol.1866 (7), p.165768-165768, Article 165768

2020

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Role of mitochondrial dysfunction and altered autophagy in cardiovascular aging and disease: from mechanisms to therapeutics

The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging

Protective Effects of α-Tocopherol, γ-Tocopherol and Oleic Acid, Three Compounds of Olive Oils, and No Effect of Trolox, on 7-Ketocholesterol-Induced Mitochondrial and Peroxisomal Dysfunction in Microglial BV-2 Cells

Propofol Related Infusion Syndrome: Ultrastructural Evidence for a Mitochondrial Disorder

Evidence for association of mitochondrial metabolism alteration with lipid accumulation in aging rats

Neonatal multiorgan failure due to ACAD9 mutation and complex I deficiency with mitochondrial hyperplasia in liver, cardiac myocytes, skeletal muscle, and renal tubules

Idebenone ameliorates statin-induced myotoxicity in atherosclerotic ApoE−/− mice by reducing oxidative stress and improving mitochondrial function

Mitochondrial remodeling underlying age-induced skeletal muscle wasting: let’s talk about sex

Preserving mitochondria to treat hypertrophic cardiomyopathy: From rare mitochondrial DNA mutation to heart failure therapy?

A stagewise response to mitochondrial dysfunction in mitochondrial DNA maintenance disorders

Iron deficiency‐induced loss of skeletal muscle mitochondrial proteins and respiratory capacity; the role of mitophagy and secretion of mitochondria‐containing vesicles

Mitochondrial Dysfunction in Heart Failure With Preserved Ejection Fraction

Current Perspectives of Mitochondria in Sepsis-Induced Cardiomyopathy

Aberrant expression of thyroidal hormone receptor α exasperating mitochondrial dysfunction induced sarcopenia in aged mice

In the eye of the storm: mitochondrial damage during heart and brain ischaemia

Mitochondrial toxicity assessment in industry - a decade of technology development and insight

Mitochondrial Potassium Channels as Pharmacological Target for Cardioprotective Drugs

Brain aging, Alzheimer's disease, and mitochondria

Mitophagy reporter mouse analysis reveals increased mitophagy activity in disuse‐induced muscle atrophy

Inhibition of the mPTP and Lipid Peroxidation Is Additively Protective Against I/R Injury

2-APQC, a small-molecule activator of Sirtuin-3 (SIRT3), alleviates myocardial hypertrophy and fibrosis by regulating mitochondrial homeostasis

Mono- and double-mutant mouse models of Parkinson's disease display severe mitochondrial damage

CMT2Q-causing mutation in the Dhtkd1 gene lead to sensory defects, mitochondrial accumulation and altered metabolism in a knock-in mouse model

Calcium-induced generation of reactive oxygen species in brain mitochondria is mediated by permeability transition

Mitochondrial ROS in myocardial ischemia reperfusion and remodeling

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