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Role of mitochondrial dysfunction and altered autophagy in cardiovascular aging and disease: from mechanisms to therapeutics

American journal of physiology. Heart and circulatory physiology, 2013-08, Vol.305 (4), p.H459-H476

2013

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The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging

Molecular cell, 2019-02, Vol.73 (4), p.775-787.e10

2019

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Protective Effects of α-Tocopherol, γ-Tocopherol and Oleic Acid, Three Compounds of Olive Oils, and No Effect of Trolox, on 7-Ketocholesterol-Induced Mitochondrial and Peroxisomal Dysfunction in Microglial BV-2 Cells

International journal of molecular sciences, 2016-11, Vol.17 (12), p.1973

2016

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Quantitative 3D electron microscopy characterization of mitochondrial structure, mitophagy, and organelle interactions in murine atrial fibrillation

Journal of structural biology, 2024-09, Vol.216 (3), p.108110, Article 108110

2024

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Mitochondrial remodeling underlying age-induced skeletal muscle wasting: let’s talk about sex

Free radical biology & medicine, 2024-06, Vol.218, p.68-81

2024

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Iron deficiency‐induced loss of skeletal muscle mitochondrial proteins and respiratory capacity; the role of mitophagy and secretion of mitochondria‐containing vesicles

The FASEB journal, 2020-05, Vol.34 (5), p.6703-6717

2020

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Mitochondrial toxicity assessment in industry - a decade of technology development and insight

Expert opinion on drug metabolism & toxicology, 2014-08, Vol.10 (8), p.1061-1067

2014

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Mitochondria and NLRP3 inflammasome in cardiac hypertrophy

Molecular and cellular biochemistry, 2024-07, Vol.479 (7), p.1571-1582

2024

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Preserving mitochondria to treat hypertrophic cardiomyopathy: From rare mitochondrial DNA mutation to heart failure therapy?

The Journal of clinical investigation, 2023-07, Vol.133 (14)

Diwan, Abhinav

2023

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Current Perspectives of Mitochondria in Sepsis-Induced Cardiomyopathy

International journal of molecular sciences, 2024-05, Vol.25 (9), p.4710

2024

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Alda-1 Ameliorates Oxidative Stress-Induced Cardiomyocyte Damage by Inhibiting the Mitochondrial ROS/TXNIP/NLRP3 Pathway

Journal of biochemical and molecular toxicology, 2024-11, Vol.38 (11), p.e70032

2024

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In the eye of the storm: mitochondrial damage during heart and brain ischaemia

The FEBS journal, 2013-10, Vol.280 (20), p.4999-5014

2013

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Mitochondrial Potassium Channels as Pharmacological Target for Cardioprotective Drugs

Medicinal research reviews, 2015-05, Vol.35 (3), p.520-553

2015

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Brain aging, Alzheimer's disease, and mitochondria

Biochimica et biophysica acta, 2011-12, Vol.1812 (12), p.1630-1639

Swerdlow, Russell H.

2011

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2-APQC, a small-molecule activator of Sirtuin-3 (SIRT3), alleviates myocardial hypertrophy and fibrosis by regulating mitochondrial homeostasis

Signal transduction and targeted therapy, 2024-05, Vol.9 (1), p.133-17, Article 133

2024

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Mono- and double-mutant mouse models of Parkinson's disease display severe mitochondrial damage

Human molecular genetics, 2007-10, Vol.16 (20), p.2377-2393

2007

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Mitochondria-to-nucleus retrograde signaling drives formation of cytoplasmic chromatin and inflammation in senescence

Genes & development, 2020-03, Vol.34 (5-6), p.428-445

2020

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The role of mitochondrial ROS in the aging brain

FEBS letters, 2018-03, Vol.592 (5), p.743-758

2018

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CMT2Q-causing mutation in the Dhtkd1 gene lead to sensory defects, mitochondrial accumulation and altered metabolism in a knock-in mouse model

Acta neuropathologica communications, 2020-03, Vol.8 (1), p.32-32, Article 32

2020

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Calcium-induced generation of reactive oxygen species in brain mitochondria is mediated by permeability transition

Free radical biology & medicine, 2008-08, Vol.45 (3), p.284-294

2008

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Mitochondrial ROS in myocardial ischemia reperfusion and remodeling

Biochimica et biophysica acta. Molecular basis of disease, 2020-07, Vol.1866 (7), p.165768-165768, Article 165768

2020

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Insulin resistance: Review of the underlying molecular mechanisms

Journal of cellular physiology, 2019-06, Vol.234 (6), p.8152-8161

2019

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Role of mitochondrial ROS in the brain: from physiology to neurodegeneration

FEBS letters, 2018-03, Vol.592 (5), p.692-702

2018

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Silencing METTL14 alleviates liver injury in non-alcoholic fatty liver disease by regulating mitochondrial homeostasis

Biomolecules & Biomedicine, 2024-05, Vol.24 (3), p.505-519

2024

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Role of Mitochondria in Ferroptosis

Molecular cell, 2019-01, Vol.73 (2), p.354-363.e3

2019

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Role of mitochondrial dysfunction and altered autophagy in cardiovascular aging and disease: from mechanisms to therapeutics

The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging

Protective Effects of α-Tocopherol, γ-Tocopherol and Oleic Acid, Three Compounds of Olive Oils, and No Effect of Trolox, on 7-Ketocholesterol-Induced Mitochondrial and Peroxisomal Dysfunction in Microglial BV-2 Cells

Quantitative 3D electron microscopy characterization of mitochondrial structure, mitophagy, and organelle interactions in murine atrial fibrillation

Mitochondrial remodeling underlying age-induced skeletal muscle wasting: let’s talk about sex

Iron deficiency‐induced loss of skeletal muscle mitochondrial proteins and respiratory capacity; the role of mitophagy and secretion of mitochondria‐containing vesicles

Mitochondrial toxicity assessment in industry - a decade of technology development and insight

Mitochondria and NLRP3 inflammasome in cardiac hypertrophy

Preserving mitochondria to treat hypertrophic cardiomyopathy: From rare mitochondrial DNA mutation to heart failure therapy?

Current Perspectives of Mitochondria in Sepsis-Induced Cardiomyopathy

Alda-1 Ameliorates Oxidative Stress-Induced Cardiomyocyte Damage by Inhibiting the Mitochondrial ROS/TXNIP/NLRP3 Pathway

In the eye of the storm: mitochondrial damage during heart and brain ischaemia

Mitochondrial Potassium Channels as Pharmacological Target for Cardioprotective Drugs

Brain aging, Alzheimer's disease, and mitochondria

2-APQC, a small-molecule activator of Sirtuin-3 (SIRT3), alleviates myocardial hypertrophy and fibrosis by regulating mitochondrial homeostasis

Mono- and double-mutant mouse models of Parkinson's disease display severe mitochondrial damage

Mitochondria-to-nucleus retrograde signaling drives formation of cytoplasmic chromatin and inflammation in senescence

The role of mitochondrial ROS in the aging brain

CMT2Q-causing mutation in the Dhtkd1 gene lead to sensory defects, mitochondrial accumulation and altered metabolism in a knock-in mouse model

Calcium-induced generation of reactive oxygen species in brain mitochondria is mediated by permeability transition

Mitochondrial ROS in myocardial ischemia reperfusion and remodeling

Insulin resistance: Review of the underlying molecular mechanisms

Role of mitochondrial ROS in the brain: from physiology to neurodegeneration

Silencing METTL14 alleviates liver injury in non-alcoholic fatty liver disease by regulating mitochondrial homeostasis

Role of Mitochondria in Ferroptosis

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