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Metabolism and Disposition of Cabozantinib in Healthy Male Volunteers and Pharmacologic Characterization of Its Major Metabolites

Drug metabolism and disposition, 2015-08, Vol.43 (8), p.1190-1207

2015

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Metformin sinusoidal efflux from the liver is consistent with negligible biliary excretion and absence of enterohepatic cycling

Drug metabolism and disposition, 2013-11, Vol.41 (11), p.1967

2013

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Recommendation to Exclude Bile-Duct-Cannulated Rats with Hyperbilirubinemia for Proper Conduct of Biliary Drug Excretion Studies

Drug metabolism and disposition, 2016-08, Vol.44 (8), p.1180-1183

2016

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Hepatobiliary toxicity of furan: identification of furan metabolites in bile of male f344/n rats

Drug metabolism and disposition, 2010-10, Vol.38 (10), p.1698

2010

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The impact of hepatic uptake on the pharmacokinetics of organic anions

Drug metabolism and disposition, 2011-10, Vol.39 (10), p.1930

2011

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In vitro and in vivo metabolism of a selective δ-opioid receptor

Drug metabolism and disposition, 2011-10, Vol.39 (10), p.1883

2011

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Hepatic and extrahepatic synthesis and disposition of dinitrophenyl-S-glutathione in bile duct-ligated rats

Drug metabolism and disposition, 2006-08, Vol.34 (8), p.1301

2006

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Biotransformation of carbon-14-labeled muraglitazar in male mice: interspecies difference in metabolic pathways leading to unique metabolites

Drug metabolism and disposition, 2006-05, Vol.34 (5), p.807

2006

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Absorption, distribution, metabolism, and excretion of donepezil (Aricept) after a single oral administration to Rat

Drug metabolism and disposition, 1999-12, Vol.27 (12), p.1406

1999

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In vivo metabolism and mass balance of 4-[4-fluorophenoxy]benzaldehyde semicarbazone in rats

Drug metabolism and disposition, 2000-10, Vol.28 (10), p.1153

2000

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Pharmacokinetics and metabolism of a RAS farnesyl transferase inhibitor in rats and dogs: in vitro-in vivo correlation

Drug metabolism and disposition, 2001-12, Vol.29 (12), p.1578

2001

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Biliary and urinary metabolic profiles of 1,2-diethyl-3-hydroxypyridin-4-one (CP94) in the rat

Drug metabolism and disposition, 2000-08, Vol.28 (8), p.873

2000

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Metabolic fate of [3H]-l-menthol in the rat

Drug metabolism and disposition, 1994-07, Vol.22 (4), p.616

1994

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Toxicokinetics of 1,2-diethylbenzene in male Sprague-Dawley rats-part 1: excretion and metabolism of [(14)C]1,2-diethylbenzene

Drug metabolism and disposition, 1999-12, Vol.27 (12), p.1470

1999

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Tissue distribution and biotransformation of zopolrestat, an aldose reductase inhibitor, in rats

Drug metabolism and disposition, 1998-11, Vol.26 (11), p.1149

1998

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Effect of its demethylated metabolite on the pharmacokinetics of unchanged TAK-603, a new antirheumatic agent, in rats

Drug metabolism and disposition, 1999-04, Vol.27 (4), p.495

1999

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Disposition, metabolism, and excretion of U-71038, a novel renin inhibitor peptide, in the rat

Drug metabolism and disposition, 1989-09, Vol.17 (5), p.518

1989

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Stereoselective metabolism of 2-phenylpropionic acid in rat. II. Studies on the organs responsible for the optical isomerization of 2-phenylpropionic acid in rat in vivo

Drug metabolism and disposition, 1987-07, Vol.15 (4), p.535

1987

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Characterization of Fasiglifam-Related Liver Toxicity in Dogs

Drug metabolism and disposition, 2019-05, Vol.47 (5), p.525-534

2019

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Identification of Novel Metabolites of Vildagliptin in Rats: Thiazoline-Containing Thiol Adducts Formed via Cysteine or Glutathione Conjugation

Drug metabolism and disposition, 2019-08, Vol.47 (8), p.809-817

2019

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In silico prediction of biliary excretion of drugs in rats based on physicochemical properties

Drug metabolism and disposition, 2010-03, Vol.38 (3), p.422

2010

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Hepatic synthesis and urinary elimination of acetaminophen glucuronide are exacerbated in bile duct-ligated rats

Drug metabolism and disposition, 2008-03, Vol.36 (3), p.475

2008

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Pharmacokinetics, tissue distribution, metabolism, and excretion of celecoxib in rats

Drug metabolism and disposition, 2000-05, Vol.28 (5), p.514

2000

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Glucuronidation and excretion of nonylphenol in perfused rat liver

Drug metabolism and disposition, 2003-08, Vol.31 (8), p.993

2003

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Dihydropyrimidine dehydrogenase activity and fluorouracil pharmacokinetics with liver damage induced by bile duct ligation in rats

Drug metabolism and disposition, 1999-06, Vol.27 (6), p.651

1999

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Metabolism and Disposition of Cabozantinib in Healthy Male Volunteers and Pharmacologic Characterization of Its Major Metabolites

Metformin sinusoidal efflux from the liver is consistent with negligible biliary excretion and absence of enterohepatic cycling

Recommendation to Exclude Bile-Duct-Cannulated Rats with Hyperbilirubinemia for Proper Conduct of Biliary Drug Excretion Studies

Hepatobiliary toxicity of furan: identification of furan metabolites in bile of male f344/n rats

The impact of hepatic uptake on the pharmacokinetics of organic anions

In vitro and in vivo metabolism of a selective δ-opioid receptor

Hepatic and extrahepatic synthesis and disposition of dinitrophenyl-S-glutathione in bile duct-ligated rats

Biotransformation of carbon-14-labeled muraglitazar in male mice: interspecies difference in metabolic pathways leading to unique metabolites

Absorption, distribution, metabolism, and excretion of donepezil (Aricept) after a single oral administration to Rat

In vivo metabolism and mass balance of 4-[4-fluorophenoxy]benzaldehyde semicarbazone in rats

Pharmacokinetics and metabolism of a RAS farnesyl transferase inhibitor in rats and dogs: in vitro-in vivo correlation

Biliary and urinary metabolic profiles of 1,2-diethyl-3-hydroxypyridin-4-one (CP94) in the rat

Metabolic fate of [3H]-l-menthol in the rat

Toxicokinetics of 1,2-diethylbenzene in male Sprague-Dawley rats-part 1: excretion and metabolism of [(14)C]1,2-diethylbenzene

Tissue distribution and biotransformation of zopolrestat, an aldose reductase inhibitor, in rats

Effect of its demethylated metabolite on the pharmacokinetics of unchanged TAK-603, a new antirheumatic agent, in rats

Disposition, metabolism, and excretion of U-71038, a novel renin inhibitor peptide, in the rat

Stereoselective metabolism of 2-phenylpropionic acid in rat. II. Studies on the organs responsible for the optical isomerization of 2-phenylpropionic acid in rat in vivo

Characterization of Fasiglifam-Related Liver Toxicity in Dogs

Identification of Novel Metabolites of Vildagliptin in Rats: Thiazoline-Containing Thiol Adducts Formed via Cysteine or Glutathione Conjugation

In silico prediction of biliary excretion of drugs in rats based on physicochemical properties

Hepatic synthesis and urinary elimination of acetaminophen glucuronide are exacerbated in bile duct-ligated rats

Pharmacokinetics, tissue distribution, metabolism, and excretion of celecoxib in rats

Glucuronidation and excretion of nonylphenol in perfused rat liver

Dihydropyrimidine dehydrogenase activity and fluorouracil pharmacokinetics with liver damage induced by bile duct ligation in rats

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