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Role of mitochondrial dysfunction and altered autophagy in cardiovascular aging and disease: from mechanisms to therapeutics

American journal of physiology. Heart and circulatory physiology, 2013-08, Vol.305 (4), p.H459-H476

2013

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The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging

Molecular cell, 2019-02, Vol.73 (4), p.775-787.e10

2019

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Protective Effects of α-Tocopherol, γ-Tocopherol and Oleic Acid, Three Compounds of Olive Oils, and No Effect of Trolox, on 7-Ketocholesterol-Induced Mitochondrial and Peroxisomal Dysfunction in Microglial BV-2 Cells

International journal of molecular sciences, 2016-11, Vol.17 (12), p.1973

2016

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Propofol Related Infusion Syndrome: Ultrastructural Evidence for a Mitochondrial Disorder

Critical care medicine, 2018-01, Vol.46 (1), p.e91-e94

2018

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Evidence for association of mitochondrial metabolism alteration with lipid accumulation in aging rats

Experimental gerontology, 2014-08, Vol.56, p.3-12

2014

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Quantitative 3D electron microscopy characterization of mitochondrial structure, mitophagy, and organelle interactions in murine atrial fibrillation

Journal of structural biology, 2024-09, Vol.216 (3), p.108110, Article 108110

2024

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Neonatal multiorgan failure due to ACAD9 mutation and complex I deficiency with mitochondrial hyperplasia in liver, cardiac myocytes, skeletal muscle, and renal tubules

Human pathology, 2016-03, Vol.49, p.27-32

2016

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Mitochondrial remodeling underlying age-induced skeletal muscle wasting: let’s talk about sex

Free radical biology & medicine, 2024-06, Vol.218, p.68-81

2024

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Iron deficiency‐induced loss of skeletal muscle mitochondrial proteins and respiratory capacity; the role of mitophagy and secretion of mitochondria‐containing vesicles

The FASEB journal, 2020-05, Vol.34 (5), p.6703-6717

2020

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Mitochondrial toxicity assessment in industry - a decade of technology development and insight

Expert opinion on drug metabolism & toxicology, 2014-08, Vol.10 (8), p.1061-1067

2014

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Mitochondria and NLRP3 inflammasome in cardiac hypertrophy

Molecular and cellular biochemistry, 2024-07, Vol.479 (7), p.1571-1582

2024

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Mitochondrial Dysfunction in Heart Failure With Preserved Ejection Fraction

Circulation (New York, N.Y.), 2019-03, Vol.139 (11), p.1435-1450

2019

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Preserving mitochondria to treat hypertrophic cardiomyopathy: From rare mitochondrial DNA mutation to heart failure therapy?

The Journal of clinical investigation, 2023-07, Vol.133 (14)

Diwan, Abhinav

2023

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Current Perspectives of Mitochondria in Sepsis-Induced Cardiomyopathy

International journal of molecular sciences, 2024-05, Vol.25 (9), p.4710

2024

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Alda-1 Ameliorates Oxidative Stress-Induced Cardiomyocyte Damage by Inhibiting the Mitochondrial ROS/TXNIP/NLRP3 Pathway

Journal of biochemical and molecular toxicology, 2024-11, Vol.38 (11), p.e70032

2024

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In the eye of the storm: mitochondrial damage during heart and brain ischaemia

The FEBS journal, 2013-10, Vol.280 (20), p.4999-5014

2013

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Mitochondrial Potassium Channels as Pharmacological Target for Cardioprotective Drugs

Medicinal research reviews, 2015-05, Vol.35 (3), p.520-553

2015

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Brain aging, Alzheimer's disease, and mitochondria

Biochimica et biophysica acta, 2011-12, Vol.1812 (12), p.1630-1639

Swerdlow, Russell H.

2011

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2-APQC, a small-molecule activator of Sirtuin-3 (SIRT3), alleviates myocardial hypertrophy and fibrosis by regulating mitochondrial homeostasis

Signal transduction and targeted therapy, 2024-05, Vol.9 (1), p.133-17, Article 133

2024

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Mitophagy reporter mouse analysis reveals increased mitophagy activity in disuse‐induced muscle atrophy

Journal of cellular physiology, 2021-11, Vol.236 (11), p.7612-7624

2021

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Mono- and double-mutant mouse models of Parkinson's disease display severe mitochondrial damage

Human molecular genetics, 2007-10, Vol.16 (20), p.2377-2393

2007

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A neuroglobin-based high-affinity ligand trap reverses carbon monoxide–induced mitochondrial poisoning

The Journal of biological chemistry, 2020-05, Vol.295 (19), p.6357-6371

2020

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Mitochondria-to-nucleus retrograde signaling drives formation of cytoplasmic chromatin and inflammation in senescence

Genes & development, 2020-03, Vol.34 (5-6), p.428-445

2020

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The role of mitochondrial ROS in the aging brain

FEBS letters, 2018-03, Vol.592 (5), p.743-758

2018

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CMT2Q-causing mutation in the Dhtkd1 gene lead to sensory defects, mitochondrial accumulation and altered metabolism in a knock-in mouse model

Acta neuropathologica communications, 2020-03, Vol.8 (1), p.32-32, Article 32

2020

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Role of mitochondrial dysfunction and altered autophagy in cardiovascular aging and disease: from mechanisms to therapeutics

The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging

Protective Effects of α-Tocopherol, γ-Tocopherol and Oleic Acid, Three Compounds of Olive Oils, and No Effect of Trolox, on 7-Ketocholesterol-Induced Mitochondrial and Peroxisomal Dysfunction in Microglial BV-2 Cells

Propofol Related Infusion Syndrome: Ultrastructural Evidence for a Mitochondrial Disorder

Evidence for association of mitochondrial metabolism alteration with lipid accumulation in aging rats

Quantitative 3D electron microscopy characterization of mitochondrial structure, mitophagy, and organelle interactions in murine atrial fibrillation

Neonatal multiorgan failure due to ACAD9 mutation and complex I deficiency with mitochondrial hyperplasia in liver, cardiac myocytes, skeletal muscle, and renal tubules

Mitochondrial remodeling underlying age-induced skeletal muscle wasting: let’s talk about sex

Iron deficiency‐induced loss of skeletal muscle mitochondrial proteins and respiratory capacity; the role of mitophagy and secretion of mitochondria‐containing vesicles

Mitochondrial toxicity assessment in industry - a decade of technology development and insight

Mitochondria and NLRP3 inflammasome in cardiac hypertrophy

Mitochondrial Dysfunction in Heart Failure With Preserved Ejection Fraction

Preserving mitochondria to treat hypertrophic cardiomyopathy: From rare mitochondrial DNA mutation to heart failure therapy?

Current Perspectives of Mitochondria in Sepsis-Induced Cardiomyopathy

Alda-1 Ameliorates Oxidative Stress-Induced Cardiomyocyte Damage by Inhibiting the Mitochondrial ROS/TXNIP/NLRP3 Pathway

In the eye of the storm: mitochondrial damage during heart and brain ischaemia

Mitochondrial Potassium Channels as Pharmacological Target for Cardioprotective Drugs

Brain aging, Alzheimer's disease, and mitochondria

2-APQC, a small-molecule activator of Sirtuin-3 (SIRT3), alleviates myocardial hypertrophy and fibrosis by regulating mitochondrial homeostasis

Mitophagy reporter mouse analysis reveals increased mitophagy activity in disuse‐induced muscle atrophy

Mono- and double-mutant mouse models of Parkinson's disease display severe mitochondrial damage

A neuroglobin-based high-affinity ligand trap reverses carbon monoxide–induced mitochondrial poisoning

Mitochondria-to-nucleus retrograde signaling drives formation of cytoplasmic chromatin and inflammation in senescence

The role of mitochondrial ROS in the aging brain

CMT2Q-causing mutation in the Dhtkd1 gene lead to sensory defects, mitochondrial accumulation and altered metabolism in a knock-in mouse model

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