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Design and Synthesis of Tetrahydropyridothieno[2,3-d]pyrimidine Scaffold Based Epidermal Growth Factor Receptor (EGFR) Kinase Inhibitors: The Role of Side Chain Chirality and Michael Acceptor Group for Maximal Potency

Journal of medicinal chemistry, 2010-10, Vol.53 (20), p.7316-7326

2010

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Anti-Influenza Drug Discovery: Structure−Activity Relationship and Mechanistic Insight into Novel Angelicin Derivatives

Journal of medicinal chemistry, 2010-02, Vol.53 (4), p.1519-1533

2010

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Identification of danthron as an isoform-specific inhibitor of HEME OXYGENASE-1/cytochrome P450 reductase interaction with anti-tumor activity

Journal of biomedical science, 2018-01, Vol.25 (1), p.6-6, Article 6

2018

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Synergistic Inhibition of Enterovirus 71 Replication by Interferon and Rupintrivir

The Journal of infectious diseases, 2011-06, Vol.203 (12), p.1784-1790

2011

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Extracellular HSP90α Induces MyD88-IRAK Complex-Associated IKKα/β-NF-κB/IRF3 and JAK2/TYK2-STAT-3 Signaling in Macrophages for Tumor-Promoting M2-Polarization

Cells (Basel, Switzerland), 2022-01, Vol.11 (2), p.229

2022

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Identification of neuraminidase inhibitors against dual H274Y/I222R mutant strains

Scientific reports, 2017-09, Vol.7 (1), p.12336-14, Article 12336

2017

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Identification of Substituted Naphthotriazolediones as Novel Tryptophan 2,3-Dioxygenase (TDO) Inhibitors through Structure-Based Virtual Screening

Journal of medicinal chemistry, 2015-10, Vol.58 (19), p.7807-7819

2015

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Suppression of Stat3 activity sensitizes gefitinib-resistant non small cell lung cancer cells

Biochemical pharmacology, 2011-06, Vol.81 (11), p.1263-1270

2011

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Identification of BPR3P0128 as an Inhibitor of Cap-Snatching Activities of Influenza Virus

Antimicrobial Agents and Chemotherapy, 2012-02, Vol.56 (2), p.647-657

2012

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Aurintricarboxylic acid inhibits influenza virus neuraminidase

Antiviral research, 2009-02, Vol.81 (2), p.123-131

2009

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Optimization of Ligand and Lipophilic Efficiency To Identify an in Vivo Active Furano-Pyrimidine Aurora Kinase Inhibitor

Journal of medicinal chemistry, 2013-07, Vol.56 (13), p.5247-5260

2013

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Inhibition of enterovirus 71 replication and the viral 3D polymerase by aurintricarboxylic acid

Journal of antimicrobial chemotherapy, 2010-04, Vol.65 (4), p.676-683

2010

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The combination effects of licl and the active leflunomide metabolite, A771726, on viral-induced interleukin 6 production and EV-A71 replication

PloS one, 2014-11, Vol.9 (11), p.e111331

2014

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Inhibition of Severe Acute Respiratory Syndrome Coronavirus Replication by Niclosamide

Antimicrobial Agents and Chemotherapy, 2004-07, Vol.48 (7), p.2693-2696

2004

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Identification of ligand efficient, fragment-like hits from an HTS library: structure-based virtual screening and docking investigations of 2H- and 3H-pyrazolo tautomers for Aurora kinase A selectivity

Journal of computer-aided molecular design, 2015-01, Vol.29 (1), p.89-100

2015

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Epstein-Barr virus BALF3 has nuclease activity and mediates mature virion production during the lytic cycle

Journal of virology, 2014-05, Vol.88 (9), p.4962-4975

2014

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Diosgenin, a Plant-Derived Sapogenin, Exhibits Antiviral Activity in Vitro against Hepatitis C Virus

Journal of natural products (Washington, D.C.), 2011-04, Vol.74 (4), p.580-584

2011

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Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules

Proceedings of the National Academy of Sciences - PNAS, 2013-05, Vol.110 (19), p.E1779-E1787

2013

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Parallel screening of wild-type and drug-resistant targets for anti-resistance neuraminidase inhibitors

PloS one, 2013-02, Vol.8 (2), p.e56704

2013

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Fast-Forwarding Hit to Lead: Aurora and Epidermal Growth Factor Receptor Kinase Inhibitor Lead Identification

Journal of medicinal chemistry, 2010-07, Vol.53 (13), p.4980-4988

2010

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Homology modeling of DFG-in FMS-like tyrosine kinase 3 (FLT3) and structure-based virtual screening for inhibitor identification

Scientific reports, 2015-06, Vol.5 (1), p.11702-11702, Article 11702

2015

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Evaluation of the antitumor effects of BPR1J-340, a potent and selective FLT3 inhibitor, alone or in combination with an HDAC inhibitor, vorinostat, in AML cancer

PloS one, 2014-01, Vol.9 (1), p.e83160

2014

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Development of an Anti-Influenza Drug Screening Assay Targeting Nucleoproteins with Tryptophan Fluorescence Quenching

Analytical chemistry (Washington), 2012-08, Vol.84 (15), p.6391-6399

2012

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Anchor-based classification and type-C inhibitors for tyrosine kinases

Scientific reports, 2015-06, Vol.5 (1), p.10938-10938, Article 10938

2015

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Structure-Based Drug Design of Novel Aurora Kinase A Inhibitors: Structural Basis for Potency and Specificity

Journal of medicinal chemistry, 2009-02, Vol.52 (4), p.1050-1062

2009

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