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Design, synthesis, and bioassay of 4-thiazolinone derivatives as influenza neuraminidase inhibitors

European journal of medicinal chemistry, 2021-03, Vol.213, p.113161, Article 113161

2021

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Modern trends in diuretics development

European journal of medicinal chemistry, 2020-12, Vol.208, p.112855-112855, Article 112855

2020

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Pyrazolo[3,4-d]pyrimidine derivatives containing a Schiff base moiety as potential antiviral agents

Bioorganic & medicinal chemistry letters, 2018-09, Vol.28 (17), p.2979-2984

2018

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Searching for new agents active against Candida albicans biofilm: A series of indole derivatives, design, synthesis and biological evaluation

European journal of medicinal chemistry, 2019-03, Vol.165, p.93-106

2019

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Discovery of ethyl ketone-based HDACs 1, 2, and 3 selective inhibitors for HIV latency reactivation

Bioorganic & medicinal chemistry letters, 2020-07, Vol.30 (13), p.127197-127197, Article 127197

2020

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Design and synthesis of aminothiazolyl norfloxacin analogues as potential antimicrobial agents and their biological evaluation

European journal of medicinal chemistry, 2019-04, Vol.167, p.105-123

2019

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Synthesis and biological evaluation of novel HIV-1 protease inhibitors using tertiary amine as P2-ligands

Bioorganic & medicinal chemistry letters, 2015-05, Vol.25 (9), p.1880-1883

2015

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Rational design of 5-((1H-imidazol-1-yl)methyl)quinolin-8-ol derivatives as novel bromodomain-containing protein 4 inhibitors

European journal of medicinal chemistry, 2019-02, Vol.163, p.281-294

2019

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Antimicrobial peptides: Structure, mechanism, and modification

European journal of medicinal chemistry, 2023-07, Vol.255, p.115377-115377, Article 115377

2023

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Evaluating the druggability of TrmD, a potential antibacterial target, through design and microbiological profiling of a series of potent TrmD inhibitors

Bioorganic & medicinal chemistry letters, 2023-06, Vol.90, p.129331-129331, Article 129331

2023

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Synthesis and anti-neuroinflammatory activity of N-heterocyclic analogs based on natural biphenyl-neolignan honokiol

Bioorganic & medicinal chemistry letters, 2019-01, Vol.29 (2), p.329-333

2019

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Design, synthesis and biological evaluation of novel FXIa inhibitors with 2-phenyl-1H-imidazole-5-carboxamide moiety as P1 fragment

European journal of medicinal chemistry, 2021-08, Vol.220, p.113437-113437, Article 113437

2021

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Design, synthesis, bioactivity and mechanism of dithioacetal derivatives containing dioxyether moiety

Bioorganic & medicinal chemistry letters, 2019-08, Vol.29 (16), p.2218-2223

2019

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Synthesis and antimicrobial studies of hydrazone derivatives of 4-[3-(2,4-difluorophenyl)-4-formyl-1H-pyrazol-1-yl]benzoic acid and 4-[3-(3,4-difluorophenyl)-4-formyl-1H-pyrazol-1-yl]benzoic acid

Bioorganic & medicinal chemistry letters, 2018-09, Vol.28 (17), p.2914-2919

2018

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A new exploration towards aminothiazolquinolone oximes as potentially multi-targeting antibacterial agents: Design, synthesis and evaluation acting on microbes, DNA, HSA and topoisomerase IV

European journal of medicinal chemistry, 2019-10, Vol.179, p.166-181

2019

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Chemical structure of hydrolysates of cereulide and their time course profile

Bioorganic & medicinal chemistry letters, 2020-05, Vol.30 (9), p.127050-127050, Article 127050

2020

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Efficient click chemistry towards novel 1H-1,2,3-triazole-tethered 4H-chromene−d-glucose conjugates: Design, synthesis and evaluation of in vitro antibacterial, MRSA and antifungal activities

European journal of medicinal chemistry, 2019-04, Vol.167, p.454-471

2019

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Isoquinolines from Corydalis tomentella from Tibet, China, possess hepatoprotective activities

Phytochemistry (Oxford), 2018-11, Vol.155, p.93-99

2018

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PRODRUGS FOR NITROREDUCTASE BASED CANCER THERAPY- 2: Novel amide/Ntr combinations targeting PC3 cancer cells

European journal of medicinal chemistry, 2019-06, Vol.171, p.383-400

2019

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Syntheses, antiviral activities and induced resistance mechanisms of novel quinazoline derivatives containing a dithioacetal moiety

Bioorganic chemistry, 2018-10, Vol.80, p.433-443

2018

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Indirubin-3′-alkoxime derivatives for upregulation of Wnt signaling through dual inhibition of GSK-3β and the CXXC5-Dvl interaction

Bioorganic chemistry, 2022-04, Vol.121, p.105664-105664, Article 105664

2022

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Discovery of deshydroxy bicalutamide derivatives as androgen receptor antagonists

European journal of medicinal chemistry, 2019-04, Vol.167, p.49-60

2019

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Biological evaluation and structure-activity relationships of imidazole-based compounds as antiprotozoal agents

European journal of medicinal chemistry, 2018-08, Vol.156, p.53-60

2018

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Discovery of novel pan-genotypic HCV NS5A inhibitors containing a novel tetracyclic core

Bioorganic & medicinal chemistry letters, 2019-03, Vol.29 (5), p.700-706

2019

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Design, synthesis, and biological evaluation of novel 7-substituted 10,11-methylenedioxy-camptothecin derivatives against drug-resistant small-cell lung cancer in vitro and in vivo

European journal of medicinal chemistry, 2022-11, Vol.241, p.114610-114610, Article 114610

2022

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Design, synthesis, and bioassay of 4-thiazolinone derivatives as influenza neuraminidase inhibitors

Modern trends in diuretics development

Pyrazolo[3,4-d]pyrimidine derivatives containing a Schiff base moiety as potential antiviral agents

Searching for new agents active against Candida albicans biofilm: A series of indole derivatives, design, synthesis and biological evaluation

Discovery of ethyl ketone-based HDACs 1, 2, and 3 selective inhibitors for HIV latency reactivation

Design and synthesis of aminothiazolyl norfloxacin analogues as potential antimicrobial agents and their biological evaluation

Synthesis and biological evaluation of novel HIV-1 protease inhibitors using tertiary amine as P2-ligands

Rational design of 5-((1H-imidazol-1-yl)methyl)quinolin-8-ol derivatives as novel bromodomain-containing protein 4 inhibitors

Antimicrobial peptides: Structure, mechanism, and modification

Evaluating the druggability of TrmD, a potential antibacterial target, through design and microbiological profiling of a series of potent TrmD inhibitors

Synthesis and anti-neuroinflammatory activity of N-heterocyclic analogs based on natural biphenyl-neolignan honokiol

Design, synthesis and biological evaluation of novel FXIa inhibitors with 2-phenyl-1H-imidazole-5-carboxamide moiety as P1 fragment

Design, synthesis, bioactivity and mechanism of dithioacetal derivatives containing dioxyether moiety

Synthesis and antimicrobial studies of hydrazone derivatives of 4-[3-(2,4-difluorophenyl)-4-formyl-1H-pyrazol-1-yl]benzoic acid and 4-[3-(3,4-difluorophenyl)-4-formyl-1H-pyrazol-1-yl]benzoic acid

A new exploration towards aminothiazolquinolone oximes as potentially multi-targeting antibacterial agents: Design, synthesis and evaluation acting on microbes, DNA, HSA and topoisomerase IV

Chemical structure of hydrolysates of cereulide and their time course profile

Efficient click chemistry towards novel 1H-1,2,3-triazole-tethered 4H-chromene−d-glucose conjugates: Design, synthesis and evaluation of in vitro antibacterial, MRSA and antifungal activities

Isoquinolines from Corydalis tomentella from Tibet, China, possess hepatoprotective activities

PRODRUGS FOR NITROREDUCTASE BASED CANCER THERAPY- 2: Novel amide/Ntr combinations targeting PC3 cancer cells

Syntheses, antiviral activities and induced resistance mechanisms of novel quinazoline derivatives containing a dithioacetal moiety

Indirubin-3′-alkoxime derivatives for upregulation of Wnt signaling through dual inhibition of GSK-3β and the CXXC5-Dvl interaction

Discovery of deshydroxy bicalutamide derivatives as androgen receptor antagonists

Biological evaluation and structure-activity relationships of imidazole-based compounds as antiprotozoal agents

Discovery of novel pan-genotypic HCV NS5A inhibitors containing a novel tetracyclic core

Design, synthesis, and biological evaluation of novel 7-substituted 10,11-methylenedioxy-camptothecin derivatives against drug-resistant small-cell lung cancer in vitro and in vivo

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