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JNJ-77242113, a highly potent, selective peptide targeting the IL-23 receptor, provides robust IL-23 pathway inhibition upon oral dosing in rats and humans

Scientific reports, 2024-07, Vol.14 (1), p.17515-12, Article 17515

2024

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Disposition of the selective cholesterol absorption inhibitor ezetimibe in healthy male subjects

Drug metabolism and disposition, 2002-04, Vol.30 (4), p.430

2002

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HPA Axis Effects of Mometasone Furoate/Formoterol (MF/F) Versus Fluticasone Propionate/Salmeterol (FP/S) Administered via Metered-Dose Inhaler (MDI

Chest, 2012-10, Vol.142 (4), p.685A-685B

2012

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Ezetimibe : A review of its metabolism, pharmacokinetics and drug interactions

Clinical pharmacokinetics, 2005-01, Vol.44 (5), p.467-494

2005

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Mometasone furoate nasal spray : A review of safety and systemic effects

Drug safety, 2007-01, Vol.30 (4), p.317-326

2007

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Effects of Ezetimibe on Cyclosporine Pharmacokinetics in Healthy Subjects

Journal of clinical pharmacology, 2006-03, Vol.46 (3), p.321-327

2006

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Pharmacokinetics of the novel PAR-1 antagonist vorapaxar in patients with hepatic impairment

European journal of clinical pharmacology, 2012-11, Vol.68 (11), p.1501-1508

2012

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The Effect of Multiple Doses of Ketoconazole or Rifampin on the Single- and Multiple-Dose Pharmacokinetics of Vorapaxar

Journal of clinical pharmacology, 2013-05, Vol.53 (5), p.540-549

2013

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No Pharmacokinetic Drug–Drug Interaction Between Prasugrel and Vorapaxar Following Multiple‐Dose Administration in Healthy Volunteers

Clinical pharmacology in drug development, 2018-02, Vol.7 (2), p.143-150

2018

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ONCE-DAILY ADMINISTRATION OF MOMETASONE FUROATE DRY POWDER INHALER HAS NO SIGNIFICANT EFFECT ON CORTISOL CONCENTRATIONS IN SUBJECTS WITH MILD-TO-MODERATE ASTHMA

Chest, 2007-10, Vol.132 (4), p.479A-479A

2007

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Neutral endopeptidase inhibition: augmented atrial and brain natriuretic peptide, haemodynamic and natriuretic responses in ovine heart failure

Clinical science (1979), 1996-09, Vol.91 (3), p.283

1996

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Pharmacodynamic interaction between the new selective cholesterol absorption inhibitor ezetimibe and simvastatin

British journal of clinical pharmacology, 2002-09, Vol.54 (3), p.309-319

2002

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Assessment of potential pharmacokinetic interactions of ezetimibe/simvastatin and extended-release niacin tablets in healthy subjects

European journal of clinical pharmacology, 2011-05, Vol.67 (5), p.483-492

2011

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A population pharmacokinetic model that describes multiple peaks due to enterohepatic recirculation of ezetimibe

Clinical therapeutics, 2001-06, Vol.23 (6), p.871-885

2001

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Comparison of the systemic bioavailability of mometasone furoate after oral inhalation from a mometasone furoate/formoterol fumarate metered-dose inhaler versus a mometasone furoate dry-powder inhaler in patients with chronic obstructive pulmonary disease

International journal of chronic obstructive pulmonary disease, 2013-01, Vol.8 (default), p.107-116

2013

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Effect of the thrombin receptor antagonist (PAR-1) vorapaxar on QT/QTc interval in healthy volunteers: A randomized, placebo- and positive-controlled, parallel group trial

Clinical pharmacology in drug development, 2014-01, Vol.3 (1), p.18-24

2014

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Pharmacodynamics and pharmacokinetics of higher-dose, double-bolus eptifibatide in percutaneous coronary intervention

Circulation (New York, N.Y.), 2001-07, Vol.104 (4), p.406-411

2001

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Effect of Food, Antacid, and Age on the Pharmacokinetics of the Oral Thrombin Receptor Antagonist Vorapaxar (SCH 530348) in Healthy Volunteers

Clinical pharmacology in drug development, 2013-07, Vol.2 (3), p.223-230

2013

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Pharmacodynamic and pharmacokinetic interaction between fenofibrate and ezetimibe

Current medical research and opinion, 2004-08, Vol.20 (8), p.1197

2004

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Pharmacodynamic interaction between ezetimibe and rosuvastatin

Current medical research and opinion, 2004-08, Vol.20 (8), p.1185-1195

2004

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Interaction of Single-Dose Ezetimibe and Steady-State Cyclosporine in Renal Transplant Patients

Journal of clinical pharmacology, 2006-03, Vol.46 (3), p.328-336

2006

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The Influence of Multiple-Dose Vorapaxar, an Oral PAR-1 Receptor Antagonist, on the Single-Dose Pharmacokinetics and Pharmacodynamics of Digoxin

Clinical pharmacology in drug development, 2013-01, Vol.2 (1), p.90-98

2013

Volltextzugriff (PDF)

The Absence of a Clinically Significant Effect of Food on the Single Dose Pharmacokinetics of Vorapaxar, a PAR-1 Antagonist, in Healthy Adult Subjects

Clinical pharmacology in drug development, 2013-10, Vol.2 (4), p.310-315

2013

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The effect of fluvastatin on the pharmacokinetics and pharmacodynamics of ezetimibe

Current medical research and opinion, 2005-08, Vol.21 (8), p.1171-1179

2005

Volltextzugriff (PDF)

Clearance receptors and endopeptidase 24.11: equal role in natriuretic peptide metabolism in conscious sheep

American journal of physiology. Regulatory, integrative and comparative physiology, 1996-08, Vol.271 (2), p.373-R380

1996

Volltextzugriff (PDF)

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JNJ-77242113, a highly potent, selective peptide targeting the IL-23 receptor, provides robust IL-23 pathway inhibition upon oral dosing in rats and humans

Disposition of the selective cholesterol absorption inhibitor ezetimibe in healthy male subjects

HPA Axis Effects of Mometasone Furoate/Formoterol (MF/F) Versus Fluticasone Propionate/Salmeterol (FP/S) Administered via Metered-Dose Inhaler (MDI

Ezetimibe : A review of its metabolism, pharmacokinetics and drug interactions

Mometasone furoate nasal spray : A review of safety and systemic effects

Effects of Ezetimibe on Cyclosporine Pharmacokinetics in Healthy Subjects

Pharmacokinetics of the novel PAR-1 antagonist vorapaxar in patients with hepatic impairment

The Effect of Multiple Doses of Ketoconazole or Rifampin on the Single- and Multiple-Dose Pharmacokinetics of Vorapaxar

No Pharmacokinetic Drug–Drug Interaction Between Prasugrel and Vorapaxar Following Multiple‐Dose Administration in Healthy Volunteers

ONCE-DAILY ADMINISTRATION OF MOMETASONE FUROATE DRY POWDER INHALER HAS NO SIGNIFICANT EFFECT ON CORTISOL CONCENTRATIONS IN SUBJECTS WITH MILD-TO-MODERATE ASTHMA

Neutral endopeptidase inhibition: augmented atrial and brain natriuretic peptide, haemodynamic and natriuretic responses in ovine heart failure

Pharmacodynamic interaction between the new selective cholesterol absorption inhibitor ezetimibe and simvastatin

Assessment of potential pharmacokinetic interactions of ezetimibe/simvastatin and extended-release niacin tablets in healthy subjects

A population pharmacokinetic model that describes multiple peaks due to enterohepatic recirculation of ezetimibe

Comparison of the systemic bioavailability of mometasone furoate after oral inhalation from a mometasone furoate/formoterol fumarate metered-dose inhaler versus a mometasone furoate dry-powder inhaler in patients with chronic obstructive pulmonary disease

Effect of the thrombin receptor antagonist (PAR-1) vorapaxar on QT/QTc interval in healthy volunteers: A randomized, placebo- and positive-controlled, parallel group trial

Pharmacodynamics and pharmacokinetics of higher-dose, double-bolus eptifibatide in percutaneous coronary intervention

Effect of Food, Antacid, and Age on the Pharmacokinetics of the Oral Thrombin Receptor Antagonist Vorapaxar (SCH 530348) in Healthy Volunteers

Pharmacodynamic and pharmacokinetic interaction between fenofibrate and ezetimibe

Pharmacodynamic interaction between ezetimibe and rosuvastatin

Interaction of Single-Dose Ezetimibe and Steady-State Cyclosporine in Renal Transplant Patients

The Influence of Multiple-Dose Vorapaxar, an Oral PAR-1 Receptor Antagonist, on the Single-Dose Pharmacokinetics and Pharmacodynamics of Digoxin

The Absence of a Clinically Significant Effect of Food on the Single Dose Pharmacokinetics of Vorapaxar, a PAR-1 Antagonist, in Healthy Adult Subjects

The effect of fluvastatin on the pharmacokinetics and pharmacodynamics of ezetimibe

Clearance receptors and endopeptidase 24.11: equal role in natriuretic peptide metabolism in conscious sheep

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