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Cyclin D-CDK4 kinase destabilizes PD-L1 via cullin 3-SPOP to control cancer immune surveillance

Nature (London), 2018-01, Vol.553 (7686), p.91-95

2018

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T cell-targeting nanoparticles focus delivery of immunotherapy to improve antitumor immunity

Nature communications, 2017-11, Vol.8 (1), p.1747-12, Article 1747

2017

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Labeling Extracellular Vesicles for Nanoscale Flow Cytometry

Scientific reports, 2017-05, Vol.7 (1), p.1878-10, Article 1878

2017

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Strength of PD-1 signaling differentially affects T-cell effector functions

Proceedings of the National Academy of Sciences - PNAS, 2013-07, Vol.110 (27), p.E2480-E2489

2013

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Metabolomic adaptations and correlates of survival to immune checkpoint blockade

Nature communications, 2019-09, Vol.10 (1), p.4346-6, Article 4346

2019

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Selective expansion of a subset of exhausted CD8 T cells by αPD-L1 blockade

Proceedings of the National Academy of Sciences - PNAS, 2008-09, Vol.105 (39), p.15016-15021

2008

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Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection

Proceedings of the National Academy of Sciences - PNAS, 2010-08, Vol.107 (33), p.14733-14738

2010

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Enhancing SIV-specific immunity in vivo by PD-1 blockade

Nature, 2009-03, Vol.458 (7235), p.206-210

2009

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Immuno-PET identifies the myeloid compartment as a key contributor to the outcome of the antitumor response under PD-1 blockade

Proceedings of the National Academy of Sciences - PNAS, 2019-08, Vol.116 (34), p.16971-16980

2019

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PD-1 blockade in chronically HIV-1-infected humanized mice suppresses viral loads

PloS one, 2013-10, Vol.8 (10), p.e77780-e77780

2013

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PRMT1 mediated methylation of cGAS suppresses anti-tumor immunity

Nature communications, 2023-05, Vol.14 (1), p.2806-2806, Article 2806

2023

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mTORC1 upregulates B7-H3/CD276 to inhibit antitumor T cells and drive tumor immune evasion

Nature communications, 2023-03, Vol.14 (1), p.1214-1214, Article 1214

2023

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Immunotherapy of chronic hepatitis C virus infection with antibodies against programmed cell death-1 (PD-1)

Proceedings of the National Academy of Sciences - PNAS, 2013-09, Vol.110 (37), p.15001-15006

2013

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USP8 inhibition reshapes an inflamed tumor microenvironment that potentiates the immunotherapy

Nature communications, 2022-03, Vol.13 (1), p.1700-1700, Article 1700

2022

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RGMb protects against acute kidney injury by inhibiting tubular cell necroptosis via an MLKL-dependent mechanism

Proceedings of the National Academy of Sciences - PNAS, 2018-02, Vol.115 (7), p.E1475-E1484

2018

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Structures of PD-1 with its ligands: Sideways and dancing cheek to cheek

Proceedings of the National Academy of Sciences - PNAS, 2008-07, Vol.105 (30), p.10275-10276

Freeman, Gordon J

2008

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Antigen-specific CD4 T-cell help rescues exhausted CD8 T cells during chronic viral infection

Proceedings of the National Academy of Sciences - PNAS, 2011-12, Vol.108 (52), p.21182-21187

2011

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ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy

Nature communications, 2023-05, Vol.14 (1), p.2859-2859, Article 2859

2023

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IL-10 and PD-L1 operate through distinct pathways to suppress T-cell activity during persistent viral infection

Proceedings of the National Academy of Sciences - PNAS, 2008-12, Vol.105 (51), p.20428-20433

2008

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PD-L1-Deficient Mice Show That PD-L1 on T Cells, Antigen-Presenting Cells, and Host Tissues Negatively Regulates T Cells

Proceedings of the National Academy of Sciences - PNAS, 2004-07, Vol.101 (29), p.10691-10696

2004

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Viral targeting of fibroblastic reticular cells contributes to immunosuppression and persistence during chronic infection

Proceedings of the National Academy of Sciences - PNAS, 2007-09, Vol.104 (39), p.15430-15435

2007

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Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease

Nature (London), 2002-01, Vol.415 (6871), p.536-541

2002

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Role of PD-1 during effector CD8 T cell differentiation

Proceedings of the National Academy of Sciences - PNAS, 2018-05, Vol.115 (18), p.4749-4754

2018

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PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation

Nature communications, 2015-03, Vol.6 (1), p.6692-6692, Article 6692

2015

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ICOS is critical for CD40-mediated antibody class switching

Nature (London), 2001-01, Vol.409 (6816), p.102-105

2001

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Cyclin D-CDK4 kinase destabilizes PD-L1 via cullin 3-SPOP to control cancer immune surveillance

T cell-targeting nanoparticles focus delivery of immunotherapy to improve antitumor immunity

Labeling Extracellular Vesicles for Nanoscale Flow Cytometry

Strength of PD-1 signaling differentially affects T-cell effector functions

Metabolomic adaptations and correlates of survival to immune checkpoint blockade

Selective expansion of a subset of exhausted CD8 T cells by αPD-L1 blockade

Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection

Enhancing SIV-specific immunity in vivo by PD-1 blockade

Immuno-PET identifies the myeloid compartment as a key contributor to the outcome of the antitumor response under PD-1 blockade

PD-1 blockade in chronically HIV-1-infected humanized mice suppresses viral loads

PRMT1 mediated methylation of cGAS suppresses anti-tumor immunity

mTORC1 upregulates B7-H3/CD276 to inhibit antitumor T cells and drive tumor immune evasion

Immunotherapy of chronic hepatitis C virus infection with antibodies against programmed cell death-1 (PD-1)

USP8 inhibition reshapes an inflamed tumor microenvironment that potentiates the immunotherapy

RGMb protects against acute kidney injury by inhibiting tubular cell necroptosis via an MLKL-dependent mechanism

Structures of PD-1 with its ligands: Sideways and dancing cheek to cheek

Antigen-specific CD4 T-cell help rescues exhausted CD8 T cells during chronic viral infection

ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy

IL-10 and PD-L1 operate through distinct pathways to suppress T-cell activity during persistent viral infection

PD-L1-Deficient Mice Show That PD-L1 on T Cells, Antigen-Presenting Cells, and Host Tissues Negatively Regulates T Cells

Viral targeting of fibroblastic reticular cells contributes to immunosuppression and persistence during chronic infection

Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease

Role of PD-1 during effector CD8 T cell differentiation

PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation

ICOS is critical for CD40-mediated antibody class switching

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