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Strength of PD-1 signaling differentially affects T-cell effector functions

Proceedings of the National Academy of Sciences - PNAS, 2013-07, Vol.110 (27), p.E2480-E2489

2013

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Selective expansion of a subset of exhausted CD8 T cells by αPD-L1 blockade

Proceedings of the National Academy of Sciences - PNAS, 2008-09, Vol.105 (39), p.15016-15021

2008

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Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection

Proceedings of the National Academy of Sciences - PNAS, 2010-08, Vol.107 (33), p.14733-14738

2010

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Immuno-PET identifies the myeloid compartment as a key contributor to the outcome of the antitumor response under PD-1 blockade

Proceedings of the National Academy of Sciences - PNAS, 2019-08, Vol.116 (34), p.16971-16980

2019

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Immunotherapy of chronic hepatitis C virus infection with antibodies against programmed cell death-1 (PD-1)

Proceedings of the National Academy of Sciences - PNAS, 2013-09, Vol.110 (37), p.15001-15006

2013

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RGMb protects against acute kidney injury by inhibiting tubular cell necroptosis via an MLKL-dependent mechanism

Proceedings of the National Academy of Sciences - PNAS, 2018-02, Vol.115 (7), p.E1475-E1484

2018

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Structures of PD-1 with its ligands: Sideways and dancing cheek to cheek

Proceedings of the National Academy of Sciences - PNAS, 2008-07, Vol.105 (30), p.10275-10276

Freeman, Gordon J

2008

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Antigen-specific CD4 T-cell help rescues exhausted CD8 T cells during chronic viral infection

Proceedings of the National Academy of Sciences - PNAS, 2011-12, Vol.108 (52), p.21182-21187

2011

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IL-10 and PD-L1 operate through distinct pathways to suppress T-cell activity during persistent viral infection

Proceedings of the National Academy of Sciences - PNAS, 2008-12, Vol.105 (51), p.20428-20433

2008

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PD-L1-Deficient Mice Show That PD-L1 on T Cells, Antigen-Presenting Cells, and Host Tissues Negatively Regulates T Cells

Proceedings of the National Academy of Sciences - PNAS, 2004-07, Vol.101 (29), p.10691-10696

2004

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Viral targeting of fibroblastic reticular cells contributes to immunosuppression and persistence during chronic infection

Proceedings of the National Academy of Sciences - PNAS, 2007-09, Vol.104 (39), p.15430-15435

2007

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Role of PD-1 during effector CD8 T cell differentiation

Proceedings of the National Academy of Sciences - PNAS, 2018-05, Vol.115 (18), p.4749-4754

2018

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PD-1/PD-L costimulatory pathway critically affects host resistance to the pathogenic fungus Histoplasma capsulatum

Proceedings of the National Academy of Sciences - PNAS, 2008-02, Vol.105 (7), p.2658-2663

2008

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Targeting Tim-1 to overcome resistance to transplantation tolerance mediated by CD8 T17 cells

Proceedings of the National Academy of Sciences - PNAS, 2009-06, Vol.106 (26), p.10734-10739

2009

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PD-1 blockade following ART interruption enhances control of pathogenic SIV in rhesus macaques

Proceedings of the National Academy of Sciences - PNAS, 2022-08, Vol.119 (33), p.e2202148119-e2202148119

2022

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Losartan controls immune checkpoint blocker-induced edema and improves survival in glioblastoma mouse models

Proceedings of the National Academy of Sciences - PNAS, 2023-02, Vol.120 (6), p.e2219199120-e2219199120

2023

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Molecular Cloning of Porimin, A Novel Cell Surface Receptor Mediating Oncotic Cell Death

Proceedings of the National Academy of Sciences - PNAS, 2001-08, Vol.98 (17), p.9778-9783

2001

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CD48-Deficient Mice Have a Pronounced Defect in CD4+T Cell Activation

Proceedings of the National Academy of Sciences - PNAS, 1999-02, Vol.96 (3), p.1019-1023

1999

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Human T-Cell Clonal Anergy is Induced by Antigen Presentation in the Absence of B7 Costimulation

Proceedings of the National Academy of Sciences - PNAS, 1993-07, Vol.90 (14), p.6586-6590

1993

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Attractin (DPPT-L), a Member of the CUB Family of Cell Adhesion and Guidance Proteins, is Secreted by Activated Human T Lymphocytes and Modulates Immune Cell Interactions

Proceedings of the National Academy of Sciences - PNAS, 1998-09, Vol.95 (19), p.11336-11341

1998

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CTLA4 Mediates Antigen-Specific Apoptosis of Human T Cells

Proceedings of the National Academy of Sciences - PNAS, 1995-01, Vol.92 (3), p.811-815

1995

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Follicular Lymphomas can be Induced to Present Alloantigen Efficiently: A Conceptual Model to Improve Their Tumor Immunogenicity

Proceedings of the National Academy of Sciences - PNAS, 1995-08, Vol.92 (18), p.8200-8204

1995

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Activated human B lymphocytes express three CTLA-4 counterreceptors that costimulate T-cell activation

Proceedings of the National Academy of Sciences - PNAS, 1993-12, Vol.90 (23), p.11059-11063

1993

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Expression and Function of the Murine B7 Antigen, the Major Costimulatory Molecule Expressed by Peritoneal Exudate Cells

Proceedings of the National Academy of Sciences - PNAS, 1992-05, Vol.89 (9), p.4210-4214

1992

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Murine B7 Antigen Provides an Efficient Costimulatory Signal for Activation of Murine T Lymphocytes via the T-Cell Receptor/CD3 Complex

Proceedings of the National Academy of Sciences - PNAS, 1992-01, Vol.89 (1), p.271-275

1992

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Strength of PD-1 signaling differentially affects T-cell effector functions

Selective expansion of a subset of exhausted CD8 T cells by αPD-L1 blockade

Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection

Immuno-PET identifies the myeloid compartment as a key contributor to the outcome of the antitumor response under PD-1 blockade

Immunotherapy of chronic hepatitis C virus infection with antibodies against programmed cell death-1 (PD-1)

RGMb protects against acute kidney injury by inhibiting tubular cell necroptosis via an MLKL-dependent mechanism

Structures of PD-1 with its ligands: Sideways and dancing cheek to cheek

Antigen-specific CD4 T-cell help rescues exhausted CD8 T cells during chronic viral infection

IL-10 and PD-L1 operate through distinct pathways to suppress T-cell activity during persistent viral infection

PD-L1-Deficient Mice Show That PD-L1 on T Cells, Antigen-Presenting Cells, and Host Tissues Negatively Regulates T Cells

Viral targeting of fibroblastic reticular cells contributes to immunosuppression and persistence during chronic infection

Role of PD-1 during effector CD8 T cell differentiation

PD-1/PD-L costimulatory pathway critically affects host resistance to the pathogenic fungus Histoplasma capsulatum

Targeting Tim-1 to overcome resistance to transplantation tolerance mediated by CD8 T17 cells

PD-1 blockade following ART interruption enhances control of pathogenic SIV in rhesus macaques

Losartan controls immune checkpoint blocker-induced edema and improves survival in glioblastoma mouse models

Molecular Cloning of Porimin, A Novel Cell Surface Receptor Mediating Oncotic Cell Death

CD48-Deficient Mice Have a Pronounced Defect in CD4+T Cell Activation

Human T-Cell Clonal Anergy is Induced by Antigen Presentation in the Absence of B7 Costimulation

Attractin (DPPT-L), a Member of the CUB Family of Cell Adhesion and Guidance Proteins, is Secreted by Activated Human T Lymphocytes and Modulates Immune Cell Interactions

CTLA4 Mediates Antigen-Specific Apoptosis of Human T Cells

Follicular Lymphomas can be Induced to Present Alloantigen Efficiently: A Conceptual Model to Improve Their Tumor Immunogenicity

Activated human B lymphocytes express three CTLA-4 counterreceptors that costimulate T-cell activation

Expression and Function of the Murine B7 Antigen, the Major Costimulatory Molecule Expressed by Peritoneal Exudate Cells

Murine B7 Antigen Provides an Efficient Costimulatory Signal for Activation of Murine T Lymphocytes via the T-Cell Receptor/CD3 Complex

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