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A regenerative approach to the treatment of multiple sclerosis

Nature (London), 2013-10, Vol.502 (7471), p.327-332

2013

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Type I interferons (alpha/beta) in immunity and autoimmunity

Annual review of immunology, 2005-01, Vol.23 (1), p.307-335

2005

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The solute carrier SLC15A4 is required for optimal trafficking of nucleic acid-sensing TLRs and ligands to endolysosomes

Proceedings of the National Academy of Sciences - PNAS, 2022-04, Vol.119 (14), p.e2200544119-e2200544119

2022

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The multiple pathways to autoimmunity

Nature immunology, 2017-07, Vol.18 (7), p.716-724

2017

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Essential requirement for IRF8 and SLC15A4 implicates plasmacytoid dendritic cells in the pathogenesis of lupus

Proceedings of the National Academy of Sciences - PNAS, 2013-02, Vol.110 (8), p.2940-2945

2013

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Lupus acceleration by a MAVS-activating RNA virus requires endosomal TLR signaling and host genetic predisposition

PloS one, 2018-09, Vol.13 (9), p.e0203118-e0203118

2018

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TLRs and interferons: a central paradigm in autoimmunity

Current opinion in immunology, 2013-12, Vol.25 (6), p.720-727

2013

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Type I interferon is a therapeutic target for virus-induced lethal vascular damage

Proceedings of the National Academy of Sciences - PNAS, 2014-06, Vol.111 (24), p.8925-8930

2014

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Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus

Proceedings of the National Academy of Sciences - PNAS, 2009-07, Vol.106 (29), p.12061-12066

2009

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Interferons as pathogenic effectors in autoimmunity

Immunological reviews, 2005-04, Vol.204 (1), p.9-26

2005

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Commitment to the regulatory T cell lineage requires CARMA1 in the thymus but not in the periphery

PLoS biology, 2009-03, Vol.7 (3), p.e51-e1000051

2009

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Systemic autoimmunity and lymphoproliferation are associated with excess IL-7 and inhibited by IL-7Rα blockade

PloS one, 2011-11, Vol.6 (11), p.e27528-e27528

2011

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An Slfn2 mutation causes lymphoid and myeloid immunodeficiency due to loss of immune cell quiescence

Nature immunology, 2010-04, Vol.11 (4), p.335-343

2010

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Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger

Proceedings of the National Academy of Sciences - PNAS, 2008-09, Vol.105 (39), p.15028-15033

2008

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The Lupus-Related Lmb3 Locus Contains a Disease-Suppressing Coronin-1A Gene Mutation

Immunity (Cambridge, Mass.), 2008-01, Vol.28 (1), p.40-51

2008

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Yip1 domain family, member 6 (Yipf6) mutation induces spontaneous intestinal inflammation in mice

Proceedings of the National Academy of Sciences - PNAS, 2012-07, Vol.109 (31), p.12650-12655

2012

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TLR-dependent and TLR-independent pathways of type I interferon induction in systemic autoimmunity

Nature medicine, 2007-05, Vol.13 (5), p.543-551

2007

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TLRs and IFNs: critical pieces of the autoimmunity puzzle

The Journal of clinical investigation, 2012-10, Vol.122 (10), p.3464-3466

Theofilopoulos, Argyrios N

2012

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Critical role of transmethylation in TLR signaling and systemic lupus erythematosus

Clinical immunology (Orlando, Fla.), 2013-05, Vol.147 (2), p.133-143

2013

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Chemoproteomic development of SLC15A4 inhibitors with anti-inflammatory activity

Nature chemical biology, 2024-01, Vol.20 (8), p.1000-1011

2024

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Anti-IFN-α/β receptor antibody treatment ameliorates disease in lupus-predisposed mice

The Journal of immunology (1950), 2012-12, Vol.189 (12), p.5976-5984

2012

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Lack of Intrinsic CTLA-4 Expression Has Minimal Effect on Regulation of Antiviral T-Cell Immunity

Journal of Virology, 2006-01, Vol.80 (1), p.270-280

2006

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Immunologic basis for development of keratoconjunctivitis sicca in systemic autoimmune diseases: Role of innate immune sensors

The ocular surface, 2024-04, Vol.32, p.130-138

2024

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Silica exposure and chronic virus infection synergistically promote lupus-like systemic autoimmunity in mice with low genetic predisposition

Clinical immunology (Orlando, Fla.), 2019-08, Vol.205, p.75-82

2019

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An agonist antibody that blocks autoimmunity by inducing anti‐inflammatory macrophages

The FASEB journal, 2016-02, Vol.30 (2), p.738-747

2016

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A regenerative approach to the treatment of multiple sclerosis

Type I interferons (alpha/beta) in immunity and autoimmunity

The solute carrier SLC15A4 is required for optimal trafficking of nucleic acid-sensing TLRs and ligands to endolysosomes

The multiple pathways to autoimmunity

Essential requirement for IRF8 and SLC15A4 implicates plasmacytoid dendritic cells in the pathogenesis of lupus

Lupus acceleration by a MAVS-activating RNA virus requires endosomal TLR signaling and host genetic predisposition

TLRs and interferons: a central paradigm in autoimmunity

Type I interferon is a therapeutic target for virus-induced lethal vascular damage

Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus

Interferons as pathogenic effectors in autoimmunity

Commitment to the regulatory T cell lineage requires CARMA1 in the thymus but not in the periphery

Systemic autoimmunity and lymphoproliferation are associated with excess IL-7 and inhibited by IL-7Rα blockade

An Slfn2 mutation causes lymphoid and myeloid immunodeficiency due to loss of immune cell quiescence

Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger

The Lupus-Related Lmb3 Locus Contains a Disease-Suppressing Coronin-1A Gene Mutation

Yip1 domain family, member 6 (Yipf6) mutation induces spontaneous intestinal inflammation in mice

TLR-dependent and TLR-independent pathways of type I interferon induction in systemic autoimmunity

TLRs and IFNs: critical pieces of the autoimmunity puzzle

Critical role of transmethylation in TLR signaling and systemic lupus erythematosus

Chemoproteomic development of SLC15A4 inhibitors with anti-inflammatory activity

Anti-IFN-α/β receptor antibody treatment ameliorates disease in lupus-predisposed mice

Lack of Intrinsic CTLA-4 Expression Has Minimal Effect on Regulation of Antiviral T-Cell Immunity

Immunologic basis for development of keratoconjunctivitis sicca in systemic autoimmune diseases: Role of innate immune sensors

Silica exposure and chronic virus infection synergistically promote lupus-like systemic autoimmunity in mice with low genetic predisposition

An agonist antibody that blocks autoimmunity by inducing anti‐inflammatory macrophages

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