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Understanding the glucoregulatory mechanisms of metformin in type 2 diabetes mellitus

Nature reviews. Endocrinology, 2019-10, Vol.15 (10), p.569-589

2019

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AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

Nature cell biology, 2011-02, Vol.13 (2), p.132-141

2011

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AMP-activated protein kinase suppresses urate crystal-induced inflammation and transduces colchicine effects in macrophages

Annals of the rheumatic diseases, 2016-01, Vol.75 (1), p.286-294

2016

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AMPK Activation Reduces Hepatic Lipid Content by Increasing Fat Oxidation In Vivo

International journal of molecular sciences, 2018-09, Vol.19 (9), p.2826

2018

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AMPK Activation Promotes Tight Junction Assembly in Intestinal Epithelial Caco-2 Cells

International journal of molecular sciences, 2019-10, Vol.20 (20), p.5171

2019

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AMP-Activated Protein Kinase Signalling

International journal of molecular sciences, 2019-02, Vol.20 (3), p.766

2019

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AMPK activation counteracts cardiac hypertrophy by reducing O-GlcNAcylation

Nature communications, 2018-01, Vol.9 (1), p.374-17, Article 374

2018

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Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

Science (American Association for the Advancement of Science), 2011-01, Vol.331 (6016), p.456-461

2011

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Metformin Antagonizes Cancer Cell Proliferation by Suppressing Mitochondrial-Dependent Biosynthesis

PLoS biology, 2015-12, Vol.13 (12), p.e1002309-e1002309

2015

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AMP-Activated Protein Kinase―Deficient Mice Are Resistant to the Metabolic Effects of Resveratrol

Diabetes (New York, N.Y.), 2010-03, Vol.59 (3), p.554-563

2010

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AMPK Activation by A-769662 Controls IL-6 Expression in Inflammatory Arthritis

PloS one, 2015-10, Vol.10 (10), p.e0140452

2015

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Aβ42 oligomers trigger synaptic loss through CAMKK2-AMPK-dependent effectors coordinating mitochondrial fission and mitophagy

Nature communications, 2022-08, Vol.13 (1), p.4444-4444, Article 4444

2022

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Discrete mechanisms of mTOR and cell cycle regulation by AMPK agonists independent of AMPK

Proceedings of the National Academy of Sciences - PNAS, 2014-01, Vol.111 (4), p.1235-1235

2014

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Motif affinity and mass spectrometry proteomic approach for the discovery of cellular AMPK targets: Identification of mitochondrial fission factor as a new AMPK substrate

Cellular signalling, 2015-05, Vol.27 (5), p.978-988

2015

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Signaling Kinase AMPK Activates Stress-Promoted Transcription via Histone H2B Phosphorylation

Science (American Association for the Advancement of Science), 2010-09, Vol.329 (5996), p.1201-1205

2010

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AICAR Antiproliferative Properties Involve the AMPK-Independent Activation of the Tumor Suppressors LATS 1 and 2

Neoplasia (New York, N.Y.), 2018-06, Vol.20 (6), p.555-562

2018

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AMPKα1‐LDH pathway regulates muscle stem cell self‐renewal by controlling metabolic homeostasis

The EMBO journal, 2017-07, Vol.36 (13), p.1946-1962

2017

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Activation of the AMP-Activated Kinase by Antidiabetes Drug Metformin Stimulates Nitric Oxide Synthesis In Vivo by Promoting the Association of Heat Shock Protein 90 and Endothelial Nitric Oxide Synthase

Diabetes (New York, N.Y.), 2006-02, Vol.55 (2), p.496-505

2006

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Upregulation of Mitochondrial Uncoupling Protein-2 by the AMP-Activated Protein Kinase in Endothelial Cells Attenuates Oxidative Stress in Diabetes

Diabetes (New York, N.Y.), 2008-12, Vol.57 (12), p.3222-3230

2008

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In Vivo Activation of AMP-Activated Protein Kinase Attenuates Diabetes-Enhanced Degradation of GTP Cyclohydrolase I

Diabetes (New York, N.Y.), 2009-08, Vol.58 (8), p.1893-1901

2009

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TIM-4 Glycoprotein-Mediated Degradation of Dying Tumor Cells by Autophagy Leads to Reduced Antigen Presentation and Increased Immune Tolerance

Immunity (Cambridge, Mass.), 2013-12, Vol.39 (6), p.1070-1081

2013

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Modulation of cardiac cAMP signaling by AMPK and its adjustments in pressure overload-induced myocardial dysfunction in rat and mouse

PloS one, 2023-09, Vol.18 (9), p.e0292015-e0292015

2023

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Nicotinamide phosphoribosyltransferase protects against ischemic stroke through SIRT1-dependent adenosine monophosphate-activated kinase pathway

Annals of neurology, 2011-02, Vol.69 (2), p.360-374

2011

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AMP-activated protein kinase (AMPK) activity is not required for neuronal development but regulates axogenesis during metabolic stress

Proceedings of the National Academy of Sciences - PNAS, 2011-04, Vol.108 (14), p.5849-5854

2011

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LKB1 and AMPK regulate synaptic remodeling in old age

Nature neuroscience, 2014-09, Vol.17 (9), p.1190-1197

2014

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Understanding the glucoregulatory mechanisms of metformin in type 2 diabetes mellitus

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

AMP-activated protein kinase suppresses urate crystal-induced inflammation and transduces colchicine effects in macrophages

AMPK Activation Reduces Hepatic Lipid Content by Increasing Fat Oxidation In Vivo

AMPK Activation Promotes Tight Junction Assembly in Intestinal Epithelial Caco-2 Cells

AMP-Activated Protein Kinase Signalling

AMPK activation counteracts cardiac hypertrophy by reducing O-GlcNAcylation

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

Metformin Antagonizes Cancer Cell Proliferation by Suppressing Mitochondrial-Dependent Biosynthesis

AMP-Activated Protein Kinase―Deficient Mice Are Resistant to the Metabolic Effects of Resveratrol

AMPK Activation by A-769662 Controls IL-6 Expression in Inflammatory Arthritis

Aβ42 oligomers trigger synaptic loss through CAMKK2-AMPK-dependent effectors coordinating mitochondrial fission and mitophagy

Discrete mechanisms of mTOR and cell cycle regulation by AMPK agonists independent of AMPK

Motif affinity and mass spectrometry proteomic approach for the discovery of cellular AMPK targets: Identification of mitochondrial fission factor as a new AMPK substrate

Signaling Kinase AMPK Activates Stress-Promoted Transcription via Histone H2B Phosphorylation

AICAR Antiproliferative Properties Involve the AMPK-Independent Activation of the Tumor Suppressors LATS 1 and 2

AMPKα1‐LDH pathway regulates muscle stem cell self‐renewal by controlling metabolic homeostasis

Activation of the AMP-Activated Kinase by Antidiabetes Drug Metformin Stimulates Nitric Oxide Synthesis In Vivo by Promoting the Association of Heat Shock Protein 90 and Endothelial Nitric Oxide Synthase

Upregulation of Mitochondrial Uncoupling Protein-2 by the AMP-Activated Protein Kinase in Endothelial Cells Attenuates Oxidative Stress in Diabetes

In Vivo Activation of AMP-Activated Protein Kinase Attenuates Diabetes-Enhanced Degradation of GTP Cyclohydrolase I

TIM-4 Glycoprotein-Mediated Degradation of Dying Tumor Cells by Autophagy Leads to Reduced Antigen Presentation and Increased Immune Tolerance

Modulation of cardiac cAMP signaling by AMPK and its adjustments in pressure overload-induced myocardial dysfunction in rat and mouse

Nicotinamide phosphoribosyltransferase protects against ischemic stroke through SIRT1-dependent adenosine monophosphate-activated kinase pathway

AMP-activated protein kinase (AMPK) activity is not required for neuronal development but regulates axogenesis during metabolic stress

LKB1 and AMPK regulate synaptic remodeling in old age

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