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Promise and challenges for direct small molecule AMPK activators

Biochemical pharmacology, 2018-07, Vol.153, p.147-158

2018

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Metformin suppresses adipogenesis through both AMP-activated protein kinase (AMPK)-dependent and AMPK-independent mechanisms

Molecular and cellular endocrinology, 2017-01, Vol.440, p.57-68

2017

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Motif affinity and mass spectrometry proteomic approach for the discovery of cellular AMPK targets: Identification of mitochondrial fission factor as a new AMPK substrate

Cellular signalling, 2015-05, Vol.27 (5), p.978-988

2015

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Activation of AMP-activated protein kinase rapidly suppresses multiple pro-inflammatory pathways in adipocytes including IL-1 receptor-associated kinase-4 phosphorylation

Molecular and cellular endocrinology, 2017-01, Vol.440, p.44-56

2017

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TIM-4 Glycoprotein-Mediated Degradation of Dying Tumor Cells by Autophagy Leads to Reduced Antigen Presentation and Increased Immune Tolerance

Immunity (Cambridge, Mass.), 2013-12, Vol.39 (6), p.1070-1081

2013

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Hypoxic activation of AMPK is dependent on mitochondrial ROS but independent of an increase in AMP/ATP ratio

Free radical biology & medicine, 2009-05, Vol.46 (10), p.1386-1391

2009

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AMPKα1 controls hepatocyte proliferation independently of energy balance by regulating Cyclin A2 expression

Journal of hepatology, 2014-01, Vol.60 (1), p.152-159

2014

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Role of AMP-activated protein kinase in autophagy and proteasome function

Biochemical and biophysical research communications, 2008-05, Vol.369 (3), p.964-968

2008

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Apoptolidins A and C activate AMPK in metabolically sensitive cell types and are mechanistically distinct from oligomycin A

Biochemical pharmacology, 2015-02, Vol.93 (3), p.251-265

2015

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Activation of Adenosine Monophosphate—Activated Protein Kinase Reduces the Onset of Diet‐Induced Hepatocellular Carcinoma in Mice

Hepatology communications, 2020-07, Vol.4 (7), p.1056-1072

2020

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Regulation of hepatic metabolism by AMPK

Journal of hepatology, 2011-04, Vol.54 (4), p.827-829

2011

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Prevention of steatohepatitis by pioglitazone: Implication of adiponectin-dependent inhibition of SREBP-1c and inflammation

Journal of hepatology, 2009-03, Vol.50 (3), p.489-500

2009

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Expanding roles for AMPK in skeletal muscle plasticity

Trends in endocrinology and metabolism, 2015-06, Vol.26 (6), p.275-286

2015

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Non-CDK-bound p27 (p27 NCDK) is a marker for cell stress and is regulated through the Akt/PKB and AMPK-kinase pathways

Experimental cell research, 2010-03, Vol.316 (5), p.762-774

2010

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Cell adhesion suppresses autophagy via Src/FAK-mediated phosphorylation and inhibition of AMPK

Cellular signalling, 2022-01, Vol.89, p.110170-110170, Article 110170

2022

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Ionizing radiation regulates the expression of AMP-activated protein kinase (AMPK) in epithelial cancer cells

Radiotherapy and oncology, 2012-03, Vol.102 (3), p.459-465

2012

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The Energy Sensor AMPK Regulates T Cell Metabolic Adaptation and Effector Responses In Vivo

Immunity (Cambridge, Mass.), 2015-01, Vol.42 (1), p.41-54

2015

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Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR

Cell, 2019-05, Vol.177 (5), p.1201-1216.e19

2019

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Abatement of aircraft noise-induced vascular disorders by exercise, fasting and pharmacological activation of α1AMPK or NRF2/HO1 pathway

Free radical biology & medicine, 2024-06, Vol.218, p.24-25

2024

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AMPK and O-GlcNAcylation, a new paradigm to protect the failing heart

Journal of molecular and cellular cardiology, 2022-12, Vol.173, p.25-25

2022

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Attenuation of aircraft noise-induced vascular dysfunction and oxidative stress by exercise, fasting and pharmacological activation of α1AMPK or NRF2/HO1 pathway

Free radical biology & medicine, 2023, Vol.208, p.S92-S93

2023

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AMPK-independent induction of autophagy by cytosolic Ca2+ increase

Cellular signalling, 2010-06, Vol.22 (6), p.914-925

2010

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CCCP induces autophagy in an AMPK-independent manner

Biochemical and biophysical research communications, 2011-12, Vol.416 (3-4), p.343-348

2011

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Role of the energy sensor AMPK in the heart: lessons learned from an inducible AMPK α1α2-knockout in mouse cardiomyocytes

Biochimica et biophysica acta. Bioenergetics, 2022-09, Vol.1863

2022

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Role of the energy sensor AMPK in the heart: lessons learned from an inducible AMPK α1α2-knockout in mouse cardiomyocytes

Biochimica et biophysica acta. Bioenergetics, 2022-09, Vol.1863, p.148891, Article 148891

2022

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Promise and challenges for direct small molecule AMPK activators

Metformin suppresses adipogenesis through both AMP-activated protein kinase (AMPK)-dependent and AMPK-independent mechanisms

Motif affinity and mass spectrometry proteomic approach for the discovery of cellular AMPK targets: Identification of mitochondrial fission factor as a new AMPK substrate

Activation of AMP-activated protein kinase rapidly suppresses multiple pro-inflammatory pathways in adipocytes including IL-1 receptor-associated kinase-4 phosphorylation

TIM-4 Glycoprotein-Mediated Degradation of Dying Tumor Cells by Autophagy Leads to Reduced Antigen Presentation and Increased Immune Tolerance

Hypoxic activation of AMPK is dependent on mitochondrial ROS but independent of an increase in AMP/ATP ratio

AMPKα1 controls hepatocyte proliferation independently of energy balance by regulating Cyclin A2 expression

Role of AMP-activated protein kinase in autophagy and proteasome function

Apoptolidins A and C activate AMPK in metabolically sensitive cell types and are mechanistically distinct from oligomycin A

Activation of Adenosine Monophosphate—Activated Protein Kinase Reduces the Onset of Diet‐Induced Hepatocellular Carcinoma in Mice

Regulation of hepatic metabolism by AMPK

Prevention of steatohepatitis by pioglitazone: Implication of adiponectin-dependent inhibition of SREBP-1c and inflammation

Expanding roles for AMPK in skeletal muscle plasticity

Non-CDK-bound p27 (p27 NCDK) is a marker for cell stress and is regulated through the Akt/PKB and AMPK-kinase pathways

Cell adhesion suppresses autophagy via Src/FAK-mediated phosphorylation and inhibition of AMPK

Ionizing radiation regulates the expression of AMP-activated protein kinase (AMPK) in epithelial cancer cells

The Energy Sensor AMPK Regulates T Cell Metabolic Adaptation and Effector Responses In Vivo

Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR

Abatement of aircraft noise-induced vascular disorders by exercise, fasting and pharmacological activation of α1AMPK or NRF2/HO1 pathway

AMPK and O-GlcNAcylation, a new paradigm to protect the failing heart

Attenuation of aircraft noise-induced vascular dysfunction and oxidative stress by exercise, fasting and pharmacological activation of α1AMPK or NRF2/HO1 pathway

AMPK-independent induction of autophagy by cytosolic Ca2+ increase

CCCP induces autophagy in an AMPK-independent manner

Role of the energy sensor AMPK in the heart: lessons learned from an inducible AMPK α1α2-knockout in mouse cardiomyocytes

Role of the energy sensor AMPK in the heart: lessons learned from an inducible AMPK α1α2-knockout in mouse cardiomyocytes

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