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Characterization of Proinsulin T Cell Epitopes Restricted by Type 1 Diabetes-Associated HLA Class II Molecules

The Journal of immunology (1950), 2020-05, Vol.204 (9), p.2349-2359

2020

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Insulin inhibits IL-10-mediated regulatory T cell function: implications for obesity

The Journal of immunology (1950), 2014-01, Vol.192 (2), p.623-629

2014

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Reversion of β-Cell Autoimmunity Changes Risk of Type 1 Diabetes: TEDDY Study

Diabetes care, 2016-09, Vol.39 (9), p.1535-1542

2016

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NK cells link obesity-induced adipose stress to inflammation and insulin resistance

Nature immunology, 2015-04, Vol.16 (4), p.376-385

2015

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Evaluation of the innate immunostimulatory potential of originator and non-originator copies of insulin glargine in an in vitro human immune model

PloS one, 2018-06, Vol.13 (6), p.e0197478-e0197478

2018

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Maladaptive immune and inflammatory pathways lead to cardiovascular insulin resistance

Metabolism, clinical and experimental, 2013-11, Vol.62 (11), p.1543-1552

2013

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Autoimmune forms of hypoglycemia

Medicine (Baltimore), 2009-05, Vol.88 (3), p.141-153

2009

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Anti-Insulin Receptor Antibodies Improve Hyperglycemia in a Mouse Model of Human Insulin Receptoropathy

Diabetes (New York, N.Y.), 2020-11, Vol.69 (11), p.2481-2489

2020

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Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease--is this type 3 diabetes?

Journal of Alzheimer's disease, 2005-02, Vol.7 (1), p.63-80

2005

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Extensive study of human insulin immunoassays: promises and pitfalls for insulin analogue detection and quantification

Clinical chemistry and laboratory medicine, 2014-03, Vol.52 (3), p.355-362

2014

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The importance of the Non Obese Diabetic (NOD) mouse model in autoimmune diabetes

Journal of autoimmunity, 2016-01, Vol.66, p.76-88

2016

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Extreme Adhesion Activity of Amyloid Fibrils Induces Subcutaneous Insulin Resistance

Diabetes (New York, N.Y.), 2019-03, Vol.68 (3), p.609-616

2019

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Anti–Insulin Receptor Antibody for Malignant Insulinoma and Refractory Hypoglycemia

The New England journal of medicine, 2023-08, Vol.389 (8), p.767-769

2023

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Hybrid Insulin Peptides Are Recognized by Human T Cells in the Context of DRB104:01

Diabetes (New York, N.Y.), 2020-07, Vol.69 (7), p.1492-1502

2020

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Type 1 diabetes mellitus: much progress, many opportunities

The Journal of clinical investigation, 2021-04, Vol.131 (8)

Powers, Alvin C

2021

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The insulin autoimmune syndrome (IAS) as a cause of hypoglycaemia: an update on the pathophysiology, biochemical investigations and diagnosis

Clinical chemistry and laboratory medicine, 2016-11, Vol.54 (11), p.1715-1724

Ismail, Adel A A

2016

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Beyond the Hormone: Insulin as an Autoimmune Target in Type 1 Diabetes

Endocrine reviews, 2011-10, Vol.32 (5), p.623-669

2011

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Beta cells transfer vesicles containing insulin to phagocytes for presentation to T cells

Proceedings of the National Academy of Sciences - PNAS, 2015-10, Vol.112 (40), p.E5496-E5502

2015

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Anti-Insulin B Cells Are Poised for Antigen Presentation in Type 1 Diabetes

The Journal of immunology (1950), 2018-08, Vol.201 (3), p.861-873

2018

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Development and Characterization of Guinea Pig Anti-Insulin Polyclonal Antibody

Applied biochemistry and biotechnology, 2024-07, Vol.196 (7), p.3675-3692

2024

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Insulin-induced cytokine production in macrophages causes insulin resistance in hepatocytes

American journal of physiology: endocrinology and metabolism, 2016-06, Vol.310 (11), p.E938-E946

2016

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Culture on a native bone marrow‐derived extracellular matrix restores the pancreatic islet basement membrane, preserves islet function, and attenuates islet immunogenicity

The FASEB journal, 2020-06, Vol.34 (6), p.8044-8056

2020

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Crinophagic granules in pancreatic β cells contribute to mouse autoimmune diabetes by diversifying pathogenic epitope repertoire

Nature communications, 2024-09, Vol.15 (1), p.8318-22, Article 8318

2024

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Insulin receptor and IRS-1 co-immunoprecipitation with SOCS-3, and IKKα/β phosphorylation are increased in obese Zucker rat skeletal muscle

Life sciences (1973), 2012-10, Vol.91 (15-16), p.816-822

2012

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Circulating β cell‐specific CD8+ T cells restricted by high‐risk HLA class I molecules show antigen experience in children with and at risk of type 1 diabetes

Clinical and experimental immunology, 2020-03, Vol.199 (3), p.263-277

2020

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Characterization of Proinsulin T Cell Epitopes Restricted by Type 1 Diabetes-Associated HLA Class II Molecules

Insulin inhibits IL-10-mediated regulatory T cell function: implications for obesity

Reversion of β-Cell Autoimmunity Changes Risk of Type 1 Diabetes: TEDDY Study

NK cells link obesity-induced adipose stress to inflammation and insulin resistance

Evaluation of the innate immunostimulatory potential of originator and non-originator copies of insulin glargine in an in vitro human immune model

Maladaptive immune and inflammatory pathways lead to cardiovascular insulin resistance

Autoimmune forms of hypoglycemia

Anti-Insulin Receptor Antibodies Improve Hyperglycemia in a Mouse Model of Human Insulin Receptoropathy

Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease--is this type 3 diabetes?

Extensive study of human insulin immunoassays: promises and pitfalls for insulin analogue detection and quantification

The importance of the Non Obese Diabetic (NOD) mouse model in autoimmune diabetes

Extreme Adhesion Activity of Amyloid Fibrils Induces Subcutaneous Insulin Resistance

Anti–Insulin Receptor Antibody for Malignant Insulinoma and Refractory Hypoglycemia

Hybrid Insulin Peptides Are Recognized by Human T Cells in the Context of DRB104:01

Type 1 diabetes mellitus: much progress, many opportunities

The insulin autoimmune syndrome (IAS) as a cause of hypoglycaemia: an update on the pathophysiology, biochemical investigations and diagnosis

Beyond the Hormone: Insulin as an Autoimmune Target in Type 1 Diabetes

Beta cells transfer vesicles containing insulin to phagocytes for presentation to T cells

Anti-Insulin B Cells Are Poised for Antigen Presentation in Type 1 Diabetes

Development and Characterization of Guinea Pig Anti-Insulin Polyclonal Antibody

Insulin-induced cytokine production in macrophages causes insulin resistance in hepatocytes

Culture on a native bone marrow‐derived extracellular matrix restores the pancreatic islet basement membrane, preserves islet function, and attenuates islet immunogenicity

Crinophagic granules in pancreatic β cells contribute to mouse autoimmune diabetes by diversifying pathogenic epitope repertoire

Insulin receptor and IRS-1 co-immunoprecipitation with SOCS-3, and IKKα/β phosphorylation are increased in obese Zucker rat skeletal muscle

Circulating β cell‐specific CD8+ T cells restricted by high‐risk HLA class I molecules show antigen experience in children with and at risk of type 1 diabetes

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