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IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome

The Journal of cell biology, 2009-12, Vol.187 (7), p.1083-1099

2009

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PIAS1 modulates striatal transcription, DNA damage repair, and SUMOylation with relevance to Huntington's disease

Proceedings of the National Academy of Sciences - PNAS, 2021-01, Vol.118 (4)

2021

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IKKβ slows Huntington’s disease progression in R6/1 mice

Proceedings of the National Academy of Sciences - PNAS, 2019-05, Vol.116 (22), p.10952-10961

2019

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Diminished LC3-Associated Phagocytosis by Huntington's Disease Striatal Astrocytes

Journal of Huntington's disease, 2022-01, Vol.11 (1), p.25

2022

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Autophagy researchers

Autophagy, 2014-02, Vol.10 (2), p.188-191

2014

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Histone Deacetylase Inhibitors Reduce Polyglutamine Toxicity

Proceedings of the National Academy of Sciences - PNAS, 2001-12, Vol.98 (26), p.15179-15184

2001

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Human Neural Progenitor Transplantation Rescues Behavior and Reduces α‐Synuclein in a Transgenic Model of Dementia with Lewy Bodies

Stem cells translational medicine, 2017-06, Vol.6 (6), p.1477-1490

2017

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Striatal Mutant Huntingtin Protein Levels Decline with Age in Homozygous Huntington's Disease Knock-In Mouse Models

Journal of Huntington's disease, 2018-01, Vol.7 (2), p.137

2018

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A bivalent Huntingtin binding peptide suppresses polyglutamine aggregation and pathogenesis in Drosophila

Nature genetics, 2002-04, Vol.30 (4), p.367-376

2002

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Longitudinal Biochemical Assay Analysis of Mutant Huntingtin Exon 1 Protein in R6/2 Mice

Journal of Huntington's disease, 2018-01, Vol.7 (4), p.321

2018

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Deletion of the huntingtin proline-rich region does not significantly affect normal huntingtin function in mice

Journal of Huntington's disease, 2012, Vol.1 (1), p.71

2012

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Targeting aggregation in the development of therapeutics for the treatment of Huntington's disease and other polyglutamine repeat diseases

Expert opinion on therapeutic targets, 2003-04, Vol.7 (2), p.201-213

2003

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Gene sequence and primary structure of mitochondrial malate dehydrogenase from Saccharomyces cerevisiae

Biochemistry (Easton), 1988-11, Vol.27 (22), p.8393-8400

1988

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Interaction of TATA-Binding Protein with Upstream Activation Factor Is Required for Activated Transcription of Ribosomal DNA by RNA Polymerase I in Saccharomyces cerevisiae In Vivo

Molecular and Cellular Biology, 1998-07, Vol.18 (7), p.3752-3761

1998

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Does Huntingtin play a role in selective macroautophagy?

Cell cycle (Georgetown, Tex.), 2010-09, Vol.9 (17), p.3401-3413

Steffan, Joan S

2010

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The role of TBP in rDNA transcription by RNA polymerase I in Saccharomyces cerevisiae: TBP is required for upstream activation factor-dependent recruitment of core factor

Genes & development, 1996-10, Vol.10 (20), p.2551-2563

1996

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RRN6 and RRN7 encode subunits of a multiprotein complex essential for the initiation of rDNA transcription by RNA polymerase I in Saccharomyces cerevisiae

Genes & development, 1994-10, Vol.8 (19), p.2349-2362

1994

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Structural and functional effects of mutations altering the subunit interface of mitochondrial malate dehydrogenase

Archives of biochemistry and biophysics, 1991-06, Vol.287 (2), p.276-282

1991

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Expression and function of heterologous forms of malate dehydrogenase in yeast

Archives of biochemistry and biophysics, 1992-02, Vol.293 (1), p.93-102

1992

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Habitat fragmentation causes immediate and time-delayed biodiversity loss at different trophic levels

Ecology letters, 2010-05, Vol.13 (5), p.597-605

2010

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Treating the whole body in Huntington's disease

Lancet neurology, 2015-11, Vol.14 (11), p.1135-1142

2015

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Extinction debt: a challenge for biodiversity conservation

Trends in ecology & evolution (Amsterdam), 2009-10, Vol.24 (10), p.564-571

2009

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Multiplexed deep sequencing analysis of ALK kinase domain identifies resistance mutations in relapsed patients following crizotinib treatment

Genomics (San Diego, Calif.), 2013-09, Vol.102 (3), p.157-162

2013

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Some Problems in the Structural Elucidation of Fungal Metabolites

Ciba Foundation Symposium 154 ‐ Bioactive Compounds from Plants, 2007, p.56-65

2007

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A COMPARISON OF IN VITRO BIOACTIVITY AND IMMUNOACTIVITY OF LUTEINIZING HORMONE IN WOMEN IN VIVO AND IN PERIFUSED FEMALE RAT PITUITARIES IN VITRO

SAWYER-STEFFAN, JOAN ELEANOR

1980

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IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome

PIAS1 modulates striatal transcription, DNA damage repair, and SUMOylation with relevance to Huntington's disease

IKKβ slows Huntington’s disease progression in R6/1 mice

Diminished LC3-Associated Phagocytosis by Huntington's Disease Striatal Astrocytes

Autophagy researchers

Histone Deacetylase Inhibitors Reduce Polyglutamine Toxicity

Human Neural Progenitor Transplantation Rescues Behavior and Reduces α‐Synuclein in a Transgenic Model of Dementia with Lewy Bodies

Striatal Mutant Huntingtin Protein Levels Decline with Age in Homozygous Huntington's Disease Knock-In Mouse Models

A bivalent Huntingtin binding peptide suppresses polyglutamine aggregation and pathogenesis in Drosophila

Longitudinal Biochemical Assay Analysis of Mutant Huntingtin Exon 1 Protein in R6/2 Mice

Deletion of the huntingtin proline-rich region does not significantly affect normal huntingtin function in mice

Targeting aggregation in the development of therapeutics for the treatment of Huntington's disease and other polyglutamine repeat diseases

Gene sequence and primary structure of mitochondrial malate dehydrogenase from Saccharomyces cerevisiae

Interaction of TATA-Binding Protein with Upstream Activation Factor Is Required for Activated Transcription of Ribosomal DNA by RNA Polymerase I in Saccharomyces cerevisiae In Vivo

Does Huntingtin play a role in selective macroautophagy?

The role of TBP in rDNA transcription by RNA polymerase I in Saccharomyces cerevisiae: TBP is required for upstream activation factor-dependent recruitment of core factor

RRN6 and RRN7 encode subunits of a multiprotein complex essential for the initiation of rDNA transcription by RNA polymerase I in Saccharomyces cerevisiae

Structural and functional effects of mutations altering the subunit interface of mitochondrial malate dehydrogenase

Expression and function of heterologous forms of malate dehydrogenase in yeast

Habitat fragmentation causes immediate and time-delayed biodiversity loss at different trophic levels

Treating the whole body in Huntington's disease

Extinction debt: a challenge for biodiversity conservation

Multiplexed deep sequencing analysis of ALK kinase domain identifies resistance mutations in relapsed patients following crizotinib treatment

Some Problems in the Structural Elucidation of Fungal Metabolites

A COMPARISON OF IN VITRO BIOACTIVITY AND IMMUNOACTIVITY OF LUTEINIZING HORMONE IN WOMEN IN VIVO AND IN PERIFUSED FEMALE RAT PITUITARIES IN VITRO

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