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Design and Discovery of an Orally Efficacious Spiroindolinone-Based Tankyrase Inhibitor for the Treatment of Colon Cancer

Journal of medicinal chemistry, 2020-04, Vol.63 (8), p.4183-4204

2020

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Discovery of Novel Spiroindoline Derivatives as Selective Tankyrase Inhibitors

Journal of medicinal chemistry, 2019-04, Vol.62 (7), p.3407-3427

2019

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Design and Synthesis of Tranylcypromine-Derived LSD1 Inhibitors with Improved hERG and Microsomal Stability Profiles

ACS medicinal chemistry letters, 2022-05, Vol.13 (5), p.848-854

2022

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Activity cliff for 7-substituted pyrrolo-pyrimidine inhibitors of HCK explained in terms of predicted basicity of the amine nitrogen

Bioorganic & medicinal chemistry, 2017-08, Vol.25 (16), p.4259-4264

2017

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Identification of pyrrolo[2,3-d]pyrimidines as potent HCK and FLT3-ITD dual inhibitors

Bioorganic & medicinal chemistry letters, 2017-11, Vol.27 (22), p.4994-4998

2017

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Investigation of the route of absorption of lipid and sugar modified leu-enkephalin analogues and their enzymatic stability using the caco-2 cell monolayer system

Medicinal chemistry (Shp-sariqah, United Arab Emirates), 2006-03, Vol.2 (2), p.203-211

2006

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Synthesis and Evaluation of a Series of Bis(pentylpyridinium) Compounds as Antifungal Agents

ChemMedChem, 2018-07, Vol.13 (14), p.1421-1436

2018

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Synthesis and in vitro evaluation of a library of modified endomorphin 1 peptides

Bioorganic & medicinal chemistry, 2008-06, Vol.16 (11), p.6286-6296

2008

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In vitro stability and permeability studies of liposomal delivery systems for a novel lipophilic endomorphin 1 analogue

International journal of pharmaceutics, 2008-05, Vol.356 (1), p.37-43

2008

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Design of bioavailable derivatives of 12-(3-adamantan-1-yl-ureido)dodecanoic acid, a potent inhibitor of the soluble epoxide hydrolase

Bioorganic & medicinal chemistry, 2007-01, Vol.15 (1), p.312-323

2007

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Synthesis, antifungal, haemolytic and cytotoxic activities of a series of bis(alkylpyridinium)alkanes

Bioorganic & medicinal chemistry, 2009-09, Vol.17 (17), p.6329-6339

2009

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Comparison of the in vitro apparent permeability and stability of opioid mimetic compounds with that of the native peptide

Bioorganic & medicinal chemistry letters, 2007-04, Vol.17 (7), p.2043-2046

2007

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Caco-2 cell permeability and stability of two d-glucopyranuronamide conjugates of thyrotropin-releasing hormone

Bioorganic & medicinal chemistry, 2007-07, Vol.15 (14), p.4946-4950

2007

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Strenuous Exercise-Induced Change in Redox State of Human Serum Albumin during Intensive Kendo Training

The Japanese Journal of Physiology, 2002, Vol.52(2), pp.135-140

2002

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In situ FTIR study of pyrazine adsorbed on Au(111), Au(100) and Au(110) electrodes

Electrochimica acta, 2000-01, Vol.45 (13), p.2075-2082

2000

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Effects of physical inactivity on aortic distensibility in visually impaired young men

European journal of applied physiology, 1999-02, Vol.79 (3), p.205-211

1999

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Plasma endothelin-1 level in athletes after exercise in a hot environment: Exercise-induced dehydration contributes to increases in plasma endothelin-1

Life sciences (1973), 1996, Vol.58 (15), p.1259-1268

1996

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ALTERATION OF LOCAL IMMUNITY IN THE ORAL CAVITY AFTER ENDURANCE RUNNING

Japanese Journal of Physical Fitness and Sports Medicine, 1998/02/01, Vol.47(1), pp.53-61

1998

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CARDIOVASCULAR FUNCTION DURING KENDO EXERCISE IN A HOT ENVIRONMENT: Effects of water replacement

Japanese Journal of Physical Fitness and Sports Medicine, 1995/04/01, Vol.44(2), pp.239-249

1995

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CARDIOVASCULAR FUNCTION DURING KENDO EXERCISE IN A HOT ENVIRONMENT

Tairyoku kagaku. Japanese journal of physical fitness and sports medicine, 1995-01, Vol.44 (2), p.239-249

1995

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EFFECTS OF REPETITIOUS INTENSE EXERCISE TRAINING ON RESTING SALIVARY IGA

Japanese Journal of Physical Fitness and Sports Medicine, 1998/04/01, Vol.47(2), pp.245-251

1998

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ALTERATION OF SALIVARY IMMUNOGLOBULIN A BY A BOUT OF EXERCISE IN THE VISUALLY IMPAIRED MALES: 視覚障害者における検討

Tairyoku kagaku. Japanese journal of physical fitness and sports medicine, 1997, Vol.46 (5), p.523-527

1997

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ALTERATION OF SALIVARY IMMUNOGLOBULIN A BY A BOUT OF EXERCISE IN THE VISUALLY IMPAIRED MALES

Japanese Journal of Physical Fitness and Sports Medicine, 1997/10/01, Vol.46(5), pp.523-527

1997

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Strenuous Exercise-Induced Change in Redox State of Human Serum Albumin during Intensive Kendo Training

JAPANESE JOURNAL PHYSIOLOGY, 2002-04, Vol.52 (2), p.135-140

2002

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高温環境下における剣道の稽古時の血行動態: 水分摂取の影響

体力科学, 1995/04/01, Vol.44(2), pp.239-249

1995

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Design and Discovery of an Orally Efficacious Spiroindolinone-Based Tankyrase Inhibitor for the Treatment of Colon Cancer

Discovery of Novel Spiroindoline Derivatives as Selective Tankyrase Inhibitors

Design and Synthesis of Tranylcypromine-Derived LSD1 Inhibitors with Improved hERG and Microsomal Stability Profiles

Activity cliff for 7-substituted pyrrolo-pyrimidine inhibitors of HCK explained in terms of predicted basicity of the amine nitrogen

Identification of pyrrolo[2,3-d]pyrimidines as potent HCK and FLT3-ITD dual inhibitors

Investigation of the route of absorption of lipid and sugar modified leu-enkephalin analogues and their enzymatic stability using the caco-2 cell monolayer system

Synthesis and Evaluation of a Series of Bis(pentylpyridinium) Compounds as Antifungal Agents

Synthesis and in vitro evaluation of a library of modified endomorphin 1 peptides

In vitro stability and permeability studies of liposomal delivery systems for a novel lipophilic endomorphin 1 analogue

Design of bioavailable derivatives of 12-(3-adamantan-1-yl-ureido)dodecanoic acid, a potent inhibitor of the soluble epoxide hydrolase

Synthesis, antifungal, haemolytic and cytotoxic activities of a series of bis(alkylpyridinium)alkanes

Comparison of the in vitro apparent permeability and stability of opioid mimetic compounds with that of the native peptide

Caco-2 cell permeability and stability of two d-glucopyranuronamide conjugates of thyrotropin-releasing hormone

Strenuous Exercise-Induced Change in Redox State of Human Serum Albumin during Intensive Kendo Training

In situ FTIR study of pyrazine adsorbed on Au(111), Au(100) and Au(110) electrodes

Effects of physical inactivity on aortic distensibility in visually impaired young men

Plasma endothelin-1 level in athletes after exercise in a hot environment: Exercise-induced dehydration contributes to increases in plasma endothelin-1

ALTERATION OF LOCAL IMMUNITY IN THE ORAL CAVITY AFTER ENDURANCE RUNNING

CARDIOVASCULAR FUNCTION DURING KENDO EXERCISE IN A HOT ENVIRONMENT: Effects of water replacement

CARDIOVASCULAR FUNCTION DURING KENDO EXERCISE IN A HOT ENVIRONMENT

EFFECTS OF REPETITIOUS INTENSE EXERCISE TRAINING ON RESTING SALIVARY IGA

ALTERATION OF SALIVARY IMMUNOGLOBULIN A BY A BOUT OF EXERCISE IN THE VISUALLY IMPAIRED MALES: 視覚障害者における検討

ALTERATION OF SALIVARY IMMUNOGLOBULIN A BY A BOUT OF EXERCISE IN THE VISUALLY IMPAIRED MALES

Strenuous Exercise-Induced Change in Redox State of Human Serum Albumin during Intensive Kendo Training

高温環境下における剣道の稽古時の血行動態: 水分摂取の影響

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