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Glucocorticoid receptor control of transcription: precision and plasticity via allostery

Nature reviews. Molecular cell biology, 2017-03, Vol.18 (3), p.159-174

2017

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Metabolic gatekeeper function of B-lymphoid transcription factors

Nature (London), 2017-02, Vol.542 (7642), p.479-483

2017

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Glucocorticoid regulation of the circadian clock modulates glucose homeostasis

Proceedings of the National Academy of Sciences - PNAS, 2009-10, Vol.106 (41), p.17582-17587

2009

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Germline signals deploy NHR-49 to modulate fatty-acid β-oxidation and desaturation in somatic tissues of C. elegans

PLoS genetics, 2014-12, Vol.10 (12), p.e1004829-e1004829

2014

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The glucocorticoid receptor dimer interface allosterically transmits sequence-specific DNA signals

Nature structural & molecular biology, 2013-07, Vol.20 (7), p.876-883

2013

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Crosstalk in Inflammation: The Interplay of Glucocorticoid Receptor-Based Mechanisms and Kinases and Phosphatases

Endocrine reviews, 2009-12, Vol.30 (7), p.830-882

2009

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Opposing Chromatin Signals Direct and Regulate the Activity of Lysine Demethylase 4C (KDM4C)

The Journal of biological chemistry, 2016-03, Vol.291 (12), p.6060-6070

2016

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Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids

Proceedings of the National Academy of Sciences - PNAS, 2007-10, Vol.104 (40), p.15858-15863

2007

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Computational resources to define alleles and altered regulatory motifs at genomically edited candidate response elements

Nucleic acids research, 2021-09, Vol.49 (16), p.9117-9131

2021

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Cell- and gene-specific regulation of primary target genes by the androgen receptor

Genes & development, 2007-08, Vol.21 (16), p.2005-2017

2007

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Determinants of cell- and gene-specific transcriptional regulation by the glucocorticoid receptor

PLoS genetics, 2007-06, Vol.3 (6), p.e94-e94

2007

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Nuclear hormone receptor NHR-49 controls fat consumption and fatty acid composition in C. elegans

PLoS biology, 2005-02, Vol.3 (2), p.e53-e53

2005

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Hic-5 is a transcription coregulator that acts before and/or after glucocorticoid receptor genome occupancy in a gene-selective manner

Proceedings of the National Academy of Sciences - PNAS, 2014-03, Vol.111 (11), p.4007-4012

2014

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A Caenorhabditis elegans Nutrient Response System Partially Dependent on Nuclear Receptor NHR-49

Proceedings of the National Academy of Sciences - PNAS, 2005-09, Vol.102 (38), p.13496-13501

2005

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The Mediator subunit MDT-15 confers metabolic adaptation to ingested material

PLoS genetics, 2008-02, Vol.4 (2), p.e1000021

2008

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Sumoylated NHR-25/NR5A regulates cell fate during C. elegans vulval development

PLoS genetics, 2013-12, Vol.9 (12), p.e1003992-e1003992

2013

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Myostatin modulates adipogenesis to generate adipocytes with favorable metabolic effects

Proceedings of the National Academy of Sciences - PNAS, 2006-10, Vol.103 (42), p.15675-15680

2006

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naturally occuring insertion of a single amino acid rewires transcriptional regulation by glucocorticoid receptor isoforms

Proceedings of the National Academy of Sciences - PNAS, 2013-10, Vol.110 (44), p.17826-17831

2013

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The Glucocorticoid Receptor and the Coregulator Brm Selectively Modulate Each Other's Occupancy and Activity in a Gene-Specific Manner

Molecular and Cellular Biology, 2011-08, Vol.31 (16), p.3267-3276

2011

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Chromatin Immunoprecipitation (ChIP) Scanning Identifies Primary Glucocorticoid Receptor Target Genes

Proceedings of the National Academy of Sciences - PNAS, 2004-11, Vol.101 (44), p.15603-15608

2004

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Non-competitive androgen receptor inhibition in vitro and in vivo

Proceedings of the National Academy of Sciences - PNAS, 2009-04, Vol.106 (17), p.7233-7238

2009

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Circadian Rhythm Gene Period 3 Is an Inhibitor of the Adipocyte Cell Fate

The Journal of biological chemistry, 2011-03, Vol.286 (11), p.9063-9070

2011

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Defects in the C. elegans acyl-CoA synthase, acs-3, and nuclear hormone receptor, nhr-25, cause sensitivity to distinct, but overlapping stresses

PloS one, 2014-03, Vol.9 (3), p.e92552

2014

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Incoherent feed-forward regulatory logic underpinning glucocorticoid receptor action

Proceedings of the National Academy of Sciences - PNAS, 2013-01, Vol.110 (5), p.1964-1969

2013

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Leveraging crowdsourcing to facilitate the discovery of new medicines

Science translational medicine, 2011-06, Vol.3 (88), p.88mr1

2011

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Glucocorticoid receptor control of transcription: precision and plasticity via allostery

Metabolic gatekeeper function of B-lymphoid transcription factors

Glucocorticoid regulation of the circadian clock modulates glucose homeostasis

Germline signals deploy NHR-49 to modulate fatty-acid β-oxidation and desaturation in somatic tissues of C. elegans

The glucocorticoid receptor dimer interface allosterically transmits sequence-specific DNA signals

Crosstalk in Inflammation: The Interplay of Glucocorticoid Receptor-Based Mechanisms and Kinases and Phosphatases

Opposing Chromatin Signals Direct and Regulate the Activity of Lysine Demethylase 4C (KDM4C)

Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids

Computational resources to define alleles and altered regulatory motifs at genomically edited candidate response elements

Cell- and gene-specific regulation of primary target genes by the androgen receptor

Determinants of cell- and gene-specific transcriptional regulation by the glucocorticoid receptor

Nuclear hormone receptor NHR-49 controls fat consumption and fatty acid composition in C. elegans

Hic-5 is a transcription coregulator that acts before and/or after glucocorticoid receptor genome occupancy in a gene-selective manner

A Caenorhabditis elegans Nutrient Response System Partially Dependent on Nuclear Receptor NHR-49

The Mediator subunit MDT-15 confers metabolic adaptation to ingested material

Sumoylated NHR-25/NR5A regulates cell fate during C. elegans vulval development

Myostatin modulates adipogenesis to generate adipocytes with favorable metabolic effects

naturally occuring insertion of a single amino acid rewires transcriptional regulation by glucocorticoid receptor isoforms

The Glucocorticoid Receptor and the Coregulator Brm Selectively Modulate Each Other's Occupancy and Activity in a Gene-Specific Manner

Chromatin Immunoprecipitation (ChIP) Scanning Identifies Primary Glucocorticoid Receptor Target Genes

Non-competitive androgen receptor inhibition in vitro and in vivo

Circadian Rhythm Gene Period 3 Is an Inhibitor of the Adipocyte Cell Fate

Defects in the C. elegans acyl-CoA synthase, acs-3, and nuclear hormone receptor, nhr-25, cause sensitivity to distinct, but overlapping stresses

Incoherent feed-forward regulatory logic underpinning glucocorticoid receptor action

Leveraging crowdsourcing to facilitate the discovery of new medicines

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