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Preparation of (4-Amino-1-Hydroxybutylidene)bisphosphonic Acid Sodium Salt, MK-217 (Alendronate Sodium). An Improved Procedure for the Preparation of 1-Hydroxy-1,1-bisphosphonic Acids

Journal of organic chemistry, 1995-12, Vol.60 (25), p.8310-8312

1995

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Synthesis of the first sulfur-35-labeled hERG radioligand

Bioorganic & medicinal chemistry letters, 2006-03, Vol.16 (6), p.1692-1695

2006

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Practical enantioselective synthesis of a homotyrosine derivative and (R,R)-4-propyl-9-hydroxynaphthoxazine, a potent dopamine agonist

Journal of organic chemistry, 1987-11, Vol.52 (23), p.5143-5150

1987

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Use of fluorous and solid-phase electrophiles as scavengers for excess amine in the preparation of sulfur-35 labelled radioligands

Journal of labelled compounds & radiopharmaceuticals, 2005-03, Vol.48 (3), p.203-208

2005

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Development of a High Specific Activity Sulfur-35-Labeled Sulfonamide Radioligand That Allowed the Identification of a New Growth Hormone Secretagogue Receptor

Journal of medicinal chemistry, 1996-04, Vol.39 (9), p.1767-1770

1996

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Synthesis of [35S]aryl sulfonyl chlorides from [35S]elemental sulfur

Journal of labelled compounds & radiopharmaceuticals, 2005-03, Vol.48 (4), p.275-283

2005

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A convenient method for [14C] carbonylation reactions

Journal of labelled compounds & radiopharmaceuticals, 2000-10, Vol.43 (11), p.1135-1144

2000

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Applications of LC-ARC™ stop-flow radiochemical detection

Journal of labelled compounds & radiopharmaceuticals, 2007-04, Vol.50 (5-6), p.543-544

2007

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Synthesis of two non-peptidyl GnRH receptor antagonists via [14C]carbonylation

Journal of labelled compounds & radiopharmaceuticals, 2003-09, Vol.46 (10), p.993-1000

2003

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Use of Dibutyl[14C]formamide as a Formylating Reagent in the Vilsmeier-Haack Reaction and Synthesis of a 14C-Labeled Novel Phosphodiesterase-4 (PDE-4) Inhibitor

Helvetica chimica acta, 2005-05, Vol.88 (5), p.1040-1047

2005

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Carbon-14 labeling of a trifluoromethoxy group: synthesis of a substance P antagonist

Journal of labelled compounds & radiopharmaceuticals, 2001-10, Vol.44 (12), p.815-829

2001

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Synthesis of [3,5-dichlorobenzenesulfonamide-U-14C)] labeled VLA-4 antagonists

Journal of labelled compounds & radiopharmaceuticals, 2004-02, Vol.47 (2), p.115-125

2004

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Ultrasonic particle size reduction of radiolabeled pharmaceuticals

Journal of labelled compounds & radiopharmaceuticals, 2004-06, Vol.47 (7), p.399-406

2004

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Synthesis of [C2H3]methotrexate and [C2H3]7-hydroxymethotrexate

Journal of labelled compounds & radiopharmaceuticals, 2002-01, Vol.45 (1), p.29-36

2002

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An enantioselective approach to (+)-thienamycin from dimethyl 1,3-acetonedicarboxylate and (+)-.alpha.-methylbenzylamine

Journal of organic chemistry, 1986-05, Vol.51 (9), p.1498-1504

1986

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Perhydroindan derivatives. XVI. Synthesis of racemic epiallogibberic acid (3)

Journal of organic chemistry, 1973-04, Vol.38 (7), p.1398-1403

1973

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Diastereoselective routes to a 1.beta.-methylcarbapenem key intermediate. Scope of ate complex formation between ester enolates and organoboranes and -alanes

Journal of organic chemistry, 1992-04, Vol.57 (8), p.2411-2418

1992

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Use of Dibutyl[ 14 C]formamide as a Formylating Reagent in the Vilsmeier – Haack Reaction and Synthesis of a 14 C‐Labeled Novel Phosphodiesterase‐4 (PDE‐4) Inhibitor

Helvetica chimica acta, 2005-05, Vol.88 (5), p.1040-1047

2005

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Synthesis of 13C-Labeled Pyrazinone Thrombin Inhibitors and Elucidation of Metabolic Activation Pathways

Helvetica chimica acta, 2004-03, Vol.87 (3), p.674-681

2004

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Synthesis of 13 C‐Labeled Pyrazinone Thrombin Inhibitors and Elucidation of Metabolic Activation Pathways

Helvetica chimica acta, 2004-03, Vol.87 (3), p.674-681

2004

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Cyclization of unsaturated hydroxylamine derivatives

Journal of organic chemistry, 1976-03, Vol.41 (5), p.855-863

1976

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Efficient utilization of [ 14C]carbon dioxide as a phosgene equivalent for labeled synthesis

Tetrahedron letters, 1997-02, Vol.38 (6), p.919-922

1997

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Perhydroindan derivatives. XV. Synthesis of a tetracyclic precursor to epiallogibberic acid

Journal of organic chemistry, 1973-02, Vol.38 (4), p.741-748

1973

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Suzuki cross-coupling for the incorporation of labeled methyl groups onto aryl halides. A synthesis of [14C]tosyl chloride and its use in the synthesis of [14C]L-738,167

Journal of labelled compounds & radiopharmaceuticals, 1999-05, Vol.42 (5), p.469-476

1999

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Diastereoselective routes to a 1β-methylcarbapenem key intermediate. Scope of ate complex formation between ester enolates and organoboranes and- alanes

Journal of organic chemistry, 1992-04, Vol.57 (8), p.2411-2418

1992

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Preparation of (4-Amino-1-Hydroxybutylidene)bisphosphonic Acid Sodium Salt, MK-217 (Alendronate Sodium). An Improved Procedure for the Preparation of 1-Hydroxy-1,1-bisphosphonic Acids

Synthesis of the first sulfur-35-labeled hERG radioligand

Practical enantioselective synthesis of a homotyrosine derivative and (R,R)-4-propyl-9-hydroxynaphthoxazine, a potent dopamine agonist

Use of fluorous and solid-phase electrophiles as scavengers for excess amine in the preparation of sulfur-35 labelled radioligands

Development of a High Specific Activity Sulfur-35-Labeled Sulfonamide Radioligand That Allowed the Identification of a New Growth Hormone Secretagogue Receptor

Synthesis of [35S]aryl sulfonyl chlorides from [35S]elemental sulfur

A convenient method for [14C] carbonylation reactions

Applications of LC-ARC™ stop-flow radiochemical detection

Synthesis of two non-peptidyl GnRH receptor antagonists via [14C]carbonylation

Use of Dibutyl[14C]formamide as a Formylating Reagent in the Vilsmeier-Haack Reaction and Synthesis of a 14C-Labeled Novel Phosphodiesterase-4 (PDE-4) Inhibitor

Carbon-14 labeling of a trifluoromethoxy group: synthesis of a substance P antagonist

Synthesis of [3,5-dichlorobenzenesulfonamide-U-14C)] labeled VLA-4 antagonists

Ultrasonic particle size reduction of radiolabeled pharmaceuticals

Synthesis of [C2H3]methotrexate and [C2H3]7-hydroxymethotrexate

An enantioselective approach to (+)-thienamycin from dimethyl 1,3-acetonedicarboxylate and (+)-.alpha.-methylbenzylamine

Perhydroindan derivatives. XVI. Synthesis of racemic epiallogibberic acid (3)

Diastereoselective routes to a 1.beta.-methylcarbapenem key intermediate. Scope of ate complex formation between ester enolates and organoboranes and -alanes

Use of Dibutyl[ 14 C]formamide as a Formylating Reagent in the Vilsmeier – Haack Reaction and Synthesis of a 14 C‐Labeled Novel Phosphodiesterase‐4 (PDE‐4) Inhibitor

Synthesis of 13C-Labeled Pyrazinone Thrombin Inhibitors and Elucidation of Metabolic Activation Pathways

Synthesis of 13 C‐Labeled Pyrazinone Thrombin Inhibitors and Elucidation of Metabolic Activation Pathways

Cyclization of unsaturated hydroxylamine derivatives

Efficient utilization of [ 14C]carbon dioxide as a phosgene equivalent for labeled synthesis

Perhydroindan derivatives. XV. Synthesis of a tetracyclic precursor to epiallogibberic acid

Suzuki cross-coupling for the incorporation of labeled methyl groups onto aryl halides. A synthesis of [14C]tosyl chloride and its use in the synthesis of [14C]L-738,167

Diastereoselective routes to a 1β-methylcarbapenem key intermediate. Scope of ate complex formation between ester enolates and organoboranes and- alanes

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