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Prime Editing: Precision Genome Editing by Reverse Transcription

Molecular cell, 2020-01, Vol.77 (2), p.210-212

2020

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Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation

Cell, 2014-10, Vol.159 (3), p.647-661

2014

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Mapping the genetic landscape of DNA double-strand break repair

Cell, 2021-10, Vol.184 (22), p.5653-5669.e25

2021

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A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response

Nature cell biology, 2012-03, Vol.14 (3), p.318-328

2012

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Efficient C•G-to-G•C base editors developed using CRISPRi screens, target-library analysis, and machine learning

Nature biotechnology, 2021-11, Vol.39 (11), p.1414-1425

2021

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A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response

Cell, 2016-12, Vol.167 (7), p.1867-1882.e21

2016

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Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation

eLife, 2016-09, Vol.5

2016

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Combinatorial single-cell CRISPR screens by direct guide RNA capture and targeted sequencing

Nature biotechnology, 2020-08, Vol.38 (8), p.954-961

2020

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Mapping the Genetic Landscape of Human Cells

Cell, 2018-08, Vol.174 (4), p.953-967.e22

2018

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chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage

Proceedings of the National Academy of Sciences - PNAS, 2010-10, Vol.107 (43), p.18475-18480

2010

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Polyubiquitinated PCNA Recruits the ZRANB3 Translocase to Maintain Genomic Integrity after Replication Stress

Molecular cell, 2012-08, Vol.47 (3), p.396-409

2012

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A Systematic Analysis of Factors Localized to Damaged Chromatin Reveals PARP-Dependent Recruitment of Transcription Factors

Cell reports (Cambridge), 2015-06, Vol.11 (9), p.1486-1500

2015

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Nuclear mechanosensing of cell confinement through biomolecular condensates

Biophysical journal, 2024-02, Vol.123 (3), p.41a-41a

2024

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Mechanochemical induction of nuclear condensates during cell confined migration

Biophysical journal, 2023-02, Vol.122 (3), p.485a-485a

2023

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Enhanced prime editing systems by manipulating cellular determinants of editing outcomes

Cell, 2021-10, Vol.184 (22), p.5635-5652.e29

2021

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Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens

Cell, 2016-12, Vol.167 (7), p.1853-1866.e17

2016

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Molecular recording of mammalian embryogenesis

Nature (London), 2019-06, Vol.570 (7759), p.77-82

2019

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A bioinformatics method identifies prominent off-targeted transcripts in RNAi screens

Nature methods, 2012-04, Vol.9 (4), p.363-366

2012

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Membrane-proximal motifs encode differences in signaling strength between type I and III interferon receptors

Science signaling, 2023-10, Vol.16 (806), p.eadf5494

2023

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Efficient prime editing in two-cell mouse embryos using PEmbryo

Nature biotechnology, 2024-02

2024

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Improving prime editing with an endogenous small RNA-binding protein

Nature (London), 2024-04, Vol.628 (8008), p.639-647

2024

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Development of a set of C•G-to-G•C transversion base editors from CRISPRi screens, target-library analysis, and machine learning

Nature biotechnology, 2021-06, Vol.39 (11), p.1414-1425

2021

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Author Correction: Efficient C•G-to-G•C base editors developed using CRISPRi screens, target-library analysis, and machine learning

Nature biotechnology, 2023-11, Vol.41 (11), p.1655-1655

2023

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Single-cell massively-parallel multiplexed microbial sequencing (M3-seq) identifies rare bacterial populations and profiles phage infection

Nature microbiology, 2023-10, Vol.8 (10), p.1846-1862

2023

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A Genome-wide Camptothecin Sensitivity Screen Identifies a Mammalian MMS22L-NFKBIL2 Complex Required for Genomic Stability

Molecular cell, 2010-11, Vol.40 (4), p.645-657

2010

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Prime Editing: Precision Genome Editing by Reverse Transcription

Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation

Mapping the genetic landscape of DNA double-strand break repair

A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response

Efficient C•G-to-G•C base editors developed using CRISPRi screens, target-library analysis, and machine learning

A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response

Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation

Combinatorial single-cell CRISPR screens by direct guide RNA capture and targeted sequencing

Mapping the Genetic Landscape of Human Cells

chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage

Polyubiquitinated PCNA Recruits the ZRANB3 Translocase to Maintain Genomic Integrity after Replication Stress

A Systematic Analysis of Factors Localized to Damaged Chromatin Reveals PARP-Dependent Recruitment of Transcription Factors

Nuclear mechanosensing of cell confinement through biomolecular condensates

Mechanochemical induction of nuclear condensates during cell confined migration

Enhanced prime editing systems by manipulating cellular determinants of editing outcomes

Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens

Molecular recording of mammalian embryogenesis

A bioinformatics method identifies prominent off-targeted transcripts in RNAi screens

Membrane-proximal motifs encode differences in signaling strength between type I and III interferon receptors

Efficient prime editing in two-cell mouse embryos using PEmbryo

Improving prime editing with an endogenous small RNA-binding protein

Development of a set of C•G-to-G•C transversion base editors from CRISPRi screens, target-library analysis, and machine learning

Author Correction: Efficient C•G-to-G•C base editors developed using CRISPRi screens, target-library analysis, and machine learning

Single-cell massively-parallel multiplexed microbial sequencing (M3-seq) identifies rare bacterial populations and profiles phage infection

A Genome-wide Camptothecin Sensitivity Screen Identifies a Mammalian MMS22L-NFKBIL2 Complex Required for Genomic Stability

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