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Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal Pneumonia in SARS-CoV-Infected Mice

Cell host & microbe, 2016-02, Vol.19 (2), p.181-193

2016

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Middle East Respiratory Syndrome: Emergence of a Pathogenic Human Coronavirus

Annual review of medicine, 2017-01, Vol.68, p.387

2017

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PARP14: A key ADP-ribosylating protein in host-virus interactions?

PLoS pathogens, 2022-06, Vol.18 (6), p.e1010535-e1010535

2022

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The coronavirus macrodomain is required to prevent PARP-mediated inhibition of virus replication and enhancement of IFN expression

PLoS pathogens, 2019-05, Vol.15 (5), p.e1007756-e1007756

2019

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Coronavirus infection and PARP expression dysregulate the NAD metabolome: An actionable component of innate immunity

The Journal of biological chemistry, 2020-12, Vol.295 (52), p.17986-17996

2020

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The Viral Macrodomain Counters Host Antiviral ADP-Ribosylation

Viruses, 2020-03, Vol.12 (4), p.384

2020

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The coronavirus nucleocapsid protein is ADP-ribosylated

Virology (New York, N.Y.), 2018-04, Vol.517, p.62-68

2018

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MERS-CoV 4b protein interferes with the NF-κB-dependent innate immune response during infection

PLoS pathogens, 2018-01, Vol.14 (1), p.e1006838-e1006838

2018

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Control the Host Cell Cycle: Viral Regulation of the Anaphase-Promoting Complex

Journal of Virology, 2013-08, Vol.87 (16), p.8818-8825

2013

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Coronaviruses: an overview of their replication and pathogenesis

Methods in molecular biology (Clifton, N.J.), 2015, Vol.1282, p.1

2015

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Cyclin A degradation by primate cytomegalovirus protein pUL21a counters its innate restriction of virus replication

PLoS pathogens, 2013-12, Vol.9 (12), p.e1003825-e1003825

2013

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The Conserved Macrodomain Is a Potential Therapeutic Target for Coronaviruses and Alphaviruses

Pathogens (Basel), 2022-01, Vol.11 (1), p.94

2022

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Viral Macrodomains: Unique Mediators of Viral Replication and Pathogenesis

Trends in microbiology (Regular ed.), 2018-07, Vol.26 (7), p.598-610

2018

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The impact of PARPs and ADP-ribosylation on inflammation and host-pathogen interactions

Genes & development, 2020-03, Vol.34 (5-6), p.341-359

2020

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An Update on the Current State of SARS-CoV-2 Mac1 Inhibitors

Pathogens (Basel), 2023-10, Vol.12 (10), p.1221

2023

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The Human Cytomegalovirus Gene UL79 Is Required for the Accumulation of Late Viral Transcripts

Journal of Virology, 2011-05, Vol.85 (10), p.4841-4852

2011

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Human Cytomegalovirus Early Protein pUL21a Promotes Efficient Viral DNA Synthesis and the Late Accumulation of Immediate-Early Transcripts

Journal of Virology, 2011-01, Vol.85 (2), p.663-674

2011

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Human Cytomegalovirus Infection of Langerhans-Type Dendritic Cells Does Not Require the Presence of the gH/gL/UL128-131A Complex and Is Blocked after Nuclear Deposition of Viral Genomes in Immature Cells

Journal of Virology, 2014-01, Vol.88 (1), p.403-416

2014

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Human Cytomegalovirus Gene UL21a Encodes a Short-Lived Cytoplasmic Protein and Facilitates Virus Replication in Fibroblasts

Journal of Virology, 2010-01, Vol.84 (1), p.291-302

2010

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IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes

The Journal of clinical investigation, 2019-09, Vol.130 (9), p.3625-3639

2019

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In Vitro and In Vivo Characterization of the Pseudomonas aeruginosa Cyclic AMP (cAMP) Phosphodiesterase CpdA, Required for cAMP Homeostasis and Virulence Factor Regulation

Journal of Bacteriology, 2010-06, Vol.192 (11), p.2779-2790

2010

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ADP‐ribosyltransferases, an update on function and nomenclature

The FEBS journal, 2022-12, Vol.289 (23), p.7399-7410

2022

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Inhibitors of One or More Cellular Aurora Kinases Impair the Replication of Herpes Simplex Virus 1 and Other DNA and RNA Viruses with Diverse Genomes and Life Cycles

Microbiology spectrum, 2023-02, Vol.11 (1), p.e0194322

2023

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β-Coronaviruses Use Lysosomes for Egress Instead of the Biosynthetic Secretory Pathway

Cell, 2020-12, Vol.183 (6), p.1520-1535.e14

2020

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Selective Packaging in Murine Coronavirus Promotes Virulence by Limiting Type I Interferon Responses

mBio, 2018-05, Vol.9 (3)

2018

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Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal Pneumonia in SARS-CoV-Infected Mice

Middle East Respiratory Syndrome: Emergence of a Pathogenic Human Coronavirus

PARP14: A key ADP-ribosylating protein in host-virus interactions?

The coronavirus macrodomain is required to prevent PARP-mediated inhibition of virus replication and enhancement of IFN expression

Coronavirus infection and PARP expression dysregulate the NAD metabolome: An actionable component of innate immunity

The Viral Macrodomain Counters Host Antiviral ADP-Ribosylation

The coronavirus nucleocapsid protein is ADP-ribosylated

MERS-CoV 4b protein interferes with the NF-κB-dependent innate immune response during infection

Control the Host Cell Cycle: Viral Regulation of the Anaphase-Promoting Complex

Coronaviruses: an overview of their replication and pathogenesis

Cyclin A degradation by primate cytomegalovirus protein pUL21a counters its innate restriction of virus replication

The Conserved Macrodomain Is a Potential Therapeutic Target for Coronaviruses and Alphaviruses

Viral Macrodomains: Unique Mediators of Viral Replication and Pathogenesis

The impact of PARPs and ADP-ribosylation on inflammation and host-pathogen interactions

An Update on the Current State of SARS-CoV-2 Mac1 Inhibitors

The Human Cytomegalovirus Gene UL79 Is Required for the Accumulation of Late Viral Transcripts

Human Cytomegalovirus Early Protein pUL21a Promotes Efficient Viral DNA Synthesis and the Late Accumulation of Immediate-Early Transcripts

Human Cytomegalovirus Infection of Langerhans-Type Dendritic Cells Does Not Require the Presence of the gH/gL/UL128-131A Complex and Is Blocked after Nuclear Deposition of Viral Genomes in Immature Cells

Human Cytomegalovirus Gene UL21a Encodes a Short-Lived Cytoplasmic Protein and Facilitates Virus Replication in Fibroblasts

IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes

In Vitro and In Vivo Characterization of the Pseudomonas aeruginosa Cyclic AMP (cAMP) Phosphodiesterase CpdA, Required for cAMP Homeostasis and Virulence Factor Regulation

ADP‐ribosyltransferases, an update on function and nomenclature

Inhibitors of One or More Cellular Aurora Kinases Impair the Replication of Herpes Simplex Virus 1 and Other DNA and RNA Viruses with Diverse Genomes and Life Cycles

β-Coronaviruses Use Lysosomes for Egress Instead of the Biosynthetic Secretory Pathway

Selective Packaging in Murine Coronavirus Promotes Virulence by Limiting Type I Interferon Responses

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