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2.3 Å resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition

Science (American Association for the Advancement of Science), 2016-02, Vol.351 (6275), p.871-875

2016

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Real-time imaging of DNA loop extrusion by condensin

Science (American Association for the Advancement of Science), 2018-04, Vol.360 (6384), p.102-105

2018

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Delicate structural coordination of the Severe Acute Respiratory Syndrome coronavirus Nsp13 upon ATP hydrolysis

Nucleic acids research, 2019-07, Vol.47 (12), p.6538-6550

2019

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Stairway to translocation: AAA+ motor structures reveal the mechanisms of ATP‐dependent substrate translocation

Protein science, 2020-02, Vol.29 (2), p.407-419

2020

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Structural mechanism of cytosolic DNA sensing by cGAS

Nature (London), 2013-06, Vol.498 (7454), p.332-337

2013

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Agonist-bound structure of the human P2Y12 receptor

Nature (London), 2014-05, Vol.509 (7498), p.119-122

2014

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A small-molecule modulator of cardiac myosin acts on multiple stages of the myosin chemomechanical cycle

The Journal of biological chemistry, 2017-10, Vol.292 (40), p.16571-16577

2017

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Structural insight into substrate and inhibitor discrimination by human P-glycoprotein

Science (American Association for the Advancement of Science), 2019-02, Vol.363 (6428), p.753-756

2019

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Quantifying intracellular rates of glycolytic and oxidative ATP production and consumption using extracellular flux measurements

The Journal of biological chemistry, 2017-04, Vol.292 (17), p.7189-7207

2017

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Structures of the calcium-activated, non-selective cation channel TRPM4

Nature (London), 2017-12, Vol.552 (7684), p.205-209

2017

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Cryo-EM structures capture the transport cycle of the P4-ATPase flippase

Science (American Association for the Advancement of Science), 2019-09, Vol.365 (6458), p.1149-1155

2019

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Structure of human argininosuccinate synthetase

Acta crystallographica. Section D, Biological crystallography., 2008-03, Vol.64 (3), p.279-286

2008

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The mechanism of eukaryotic CMG helicase activation

Nature (London), 2018-03, Vol.555 (7695), p.265-268

2018

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Molecular structure of human P-glycoprotein in the ATP-bound, outward-facing conformation

Science (American Association for the Advancement of Science), 2018-02, Vol.359 (6378), p.915-919

2018

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Light-driven dinitrogen reduction catalyzed by a CdS:nitrogenase MoFe protein biohybrid

Science (American Association for the Advancement of Science), 2016-04, Vol.352 (6284), p.448-450

2016

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Mechanism of allosteric modulation of P-glycoprotein by transport substrates and inhibitors

Science (American Association for the Advancement of Science), 2019-05, Vol.364 (6441), p.689-692

2019

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mTOR kinase structure, mechanism and regulation

Nature (London), 2013-05, Vol.497 (7448), p.217-223

2013

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Unraveling the Mechanism of Protein Disaggregation Through a ClpB-DnaK Interaction

Science (American Association for the Advancement of Science), 2013-03, Vol.339 (6123), p.1080-1083

2013

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Atomic model for the membrane-embedded V O motor of a eukaryotic V-ATPase

Nature (London), 2016-11, Vol.539 (7627), p.118

2016

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A label-free fluorescent molecular beacon based on DNA-templated silver nanoclusters for detection of adenosine and adenosine deaminase

Chemical communications (Cambridge, England), 2012-01, Vol.48 (44), p.5488-5490

2012

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Molecular mechanism of ATP binding and ion channel activation in P2X receptors

Nature (London), 2012-05, Vol.485 (7397), p.207-212

2012

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Multidrug Resistance Protein 1 (MRP1, ABCC1), a “Multitasking” ATP-binding Cassette (ABC) Transporter

The Journal of biological chemistry, 2014-11, Vol.289 (45), p.30880-30888

Cole, Susan P.C.

2014

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Adenosine triphosphate responsive metal-organic frameworks equipped with a DNA structure lock for construction of a ratiometric SERS biosensor

Chemical communications (Cambridge, England), 2020-01, Vol.56 (9), p.1413-1416

2020

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A highly potent and selective Vps34 inhibitor alters vesicle trafficking and autophagy

Nature chemical biology, 2014-12, Vol.10 (12), p.1013-1019

2014

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A target responsive aptamer machine for label-free and sensitive non-enzymatic recycling amplification detection of ATP

Chemical communications (Cambridge, England), 2016-01, Vol.52 (18), p.3673-3676

2016

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2.3 Å resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition

Real-time imaging of DNA loop extrusion by condensin

Delicate structural coordination of the Severe Acute Respiratory Syndrome coronavirus Nsp13 upon ATP hydrolysis

Stairway to translocation: AAA+ motor structures reveal the mechanisms of ATP‐dependent substrate translocation

Structural mechanism of cytosolic DNA sensing by cGAS

Agonist-bound structure of the human P2Y12 receptor

A small-molecule modulator of cardiac myosin acts on multiple stages of the myosin chemomechanical cycle

Structural insight into substrate and inhibitor discrimination by human P-glycoprotein

Quantifying intracellular rates of glycolytic and oxidative ATP production and consumption using extracellular flux measurements

Structures of the calcium-activated, non-selective cation channel TRPM4

Cryo-EM structures capture the transport cycle of the P4-ATPase flippase

Structure of human argininosuccinate synthetase

The mechanism of eukaryotic CMG helicase activation

Molecular structure of human P-glycoprotein in the ATP-bound, outward-facing conformation

Light-driven dinitrogen reduction catalyzed by a CdS:nitrogenase MoFe protein biohybrid

Mechanism of allosteric modulation of P-glycoprotein by transport substrates and inhibitors

mTOR kinase structure, mechanism and regulation

Unraveling the Mechanism of Protein Disaggregation Through a ClpB-DnaK Interaction

Atomic model for the membrane-embedded V O motor of a eukaryotic V-ATPase

A label-free fluorescent molecular beacon based on DNA-templated silver nanoclusters for detection of adenosine and adenosine deaminase

Molecular mechanism of ATP binding and ion channel activation in P2X receptors

Multidrug Resistance Protein 1 (MRP1, ABCC1), a “Multitasking” ATP-binding Cassette (ABC) Transporter

Adenosine triphosphate responsive metal-organic frameworks equipped with a DNA structure lock for construction of a ratiometric SERS biosensor

A highly potent and selective Vps34 inhibitor alters vesicle trafficking and autophagy

A target responsive aptamer machine for label-free and sensitive non-enzymatic recycling amplification detection of ATP

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