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Reconstitution of human microglia and resident T cells in the brain of humanized DRAGA mice

Frontiers in cellular and infection microbiology, 2024-06, Vol.14, p.1367566

2024

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The humanized DRAGA mouse (HLA-A2. HLA-DR4. RAG1 KO. IL-2R g c KO. NOD) establishes inducible and transmissible models for influenza type A infections

Human vaccines & immunotherapeutics, 2020-09, Vol.16 (9), p.2222-2237

2020

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Human-Immune-System (HIS) humanized mouse model (DRAGA: HLA-A2.HLA-DR4.Rag1KO.IL-2RγcKO.NOD) for COVID-19

Human vaccines & immunotherapeutics, 2022-11, Vol.18 (5), p.2048622-2048622

2022

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Generation and testing anti-influenza human monoclonal antibodies in a new humanized mouse model (DRAGA: HLA-A2. HLA-DR4. Rag1 KO. IL-2Rγc KO. NOD)

Human vaccines & immunotherapeutics, 2018-02, Vol.14 (2), p.345-360

2018

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Humanized DRAGA mice immunized with Plasmodium falciparum sporozoites and chloroquine elicit protective pre-erythrocytic immunity

Malaria journal, 2018-03, Vol.17 (1), p.114-114, Article 114

2018

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Differential effect of HLA class-I versus class-II transgenes on human T and B cell reconstitution and function in NRG mice

Scientific reports, 2016-06, Vol.6 (1), p.28093-28093, Article 28093

2016

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Nonobese Diabetic (NOD) Mice Lack a Protective B-Cell Response against the “Nonlethal” Plasmodium yoelii 17XNL Malaria Protozoan

Malaria research and treatment, 2016, Vol.2016, p.6132734-9

2016

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Long-term silencing of autoimmune diabetes and improved life expectancy by a soluble pHLA-DR4 chimera in a newly-humanized NOD/DR4/B7 mouse

Human vaccines & immunotherapeutics, 2014-03, Vol.10 (3), p.693-699

2014

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Humanized HLA-DR4.RagKO.IL2RγcKO.NOD (DRAG) mice sustain the complex vertebrate life cycle of Plasmodium falciparum malaria

Malaria journal, 2014-09, Vol.13 (1), p.386-386, Article 386

2014

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Down-regulation of autoreactive T-cells by HMG CoA reductase inhibitors

Clinical Immunology, 2006-04, Vol.119 (1), p.1-12

2006

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Differential partitioning and trafficking of GM gangliosides and cholesterol-rich lipid rafts in thymic and splenic CD4 T cells

Molecular Immunology, 2007, Vol.44 (4), p.530-540

2007

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Differential effect of CD4+ Foxp3+ T-regulatory cells on the B and T helper cell responses to influenza virus vaccination

Vaccine, 2010-10, Vol.28 (45), p.7319-7330

2010

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Soluble, dimeric HLA DR4‐peptide chimeras: An approach for detection and immunoregulation of human type‐1 diabetes

European Journal of Immunology, 2005-09, Vol.35 (9), p.2762-2775

2005

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Antigen-specific downregulation of T cells by doxorubicin delivered through a recombinant MHC II-peptide chimera

Nature biotechnology, 2001-02, Vol.19 (2), p.142-147

2001

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RNA degradation precedes DNA cleavage in autoreactive CD4 T cells suppressed by calicheamicin γ1

International immunopharmacology, 2004-04, Vol.4 (4), p.521-526

2004

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Reversal of type 1 diabetes by a new MHC II‐peptide chimera: “Single‐epitope‐mediated suppression” to stabilize a polyclonal autoimmune T‐cell process

European journal of immunology, 2010-08, Vol.40 (8), p.2277-2288

2010

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Efficacy of clonal deletion vs. anergy of self-reactive CD4 T-cells for the prevention and reversal of autoimmune diabetes

Journal of autoimmunity, 2005-08, Vol.25 (1), p.21-32

2005

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Enzymatically mediated engineering of multivalent MHC class II–peptide chimeras

Protein engineering, 2001-03, Vol.14 (3), p.195-200

2001

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Analysis of lipid rafts in T cells

Molecular immunology, 2004-06, Vol.41 (4), p.399-409

2004

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CD28 Signaling in T Regulatory Precursors Requires p56lck and Rafts Integrity to Stabilize the Foxp3 Message

The Journal of immunology (1950), 2009-01, Vol.182 (1), p.102-110

2009

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A peptide-major histocompatibility complex II chimera favors survival of pancreatic beta-islets grafted in type 1 diabetic mice

Transplantation, 2008-06, Vol.85 (12), p.1717

2008

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Immunopotency of a viral peptide assembled on the carbohydrate moieties of self immunoglobulins

Nature biotechnology, 1996-06, Vol.14 (6), p.722-725

1996

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Antineoplastic efficacy of doxorubicin enzymatically assembled on galactose residues of a monoclonal antibody specific for the carcinoembryonic antigen

Cancer research (Chicago, Ill.), 1999, Vol.59 (1), p.115-121

1999

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Role of lipid rafts in T cells

Archivum Immunologiae et Therapiae Experimentalis, 2004-07, Vol.52 (4), p.215-224

2004

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Thymic Development of CD4+25hi Foxp3+ T-Regulatory Cells Echoes their Suppressogenic Capacity in Periphery

The Open autoimmunity journal, 2009-07, Vol.1 (1), p.64-78

2009

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Reconstitution of human microglia and resident T cells in the brain of humanized DRAGA mice

The humanized DRAGA mouse (HLA-A2. HLA-DR4. RAG1 KO. IL-2R g c KO. NOD) establishes inducible and transmissible models for influenza type A infections

Human-Immune-System (HIS) humanized mouse model (DRAGA: HLA-A2.HLA-DR4.Rag1KO.IL-2RγcKO.NOD) for COVID-19

Generation and testing anti-influenza human monoclonal antibodies in a new humanized mouse model (DRAGA: HLA-A2. HLA-DR4. Rag1 KO. IL-2Rγc KO. NOD)

Humanized DRAGA mice immunized with Plasmodium falciparum sporozoites and chloroquine elicit protective pre-erythrocytic immunity

Differential effect of HLA class-I versus class-II transgenes on human T and B cell reconstitution and function in NRG mice

Nonobese Diabetic (NOD) Mice Lack a Protective B-Cell Response against the “Nonlethal” Plasmodium yoelii 17XNL Malaria Protozoan

Long-term silencing of autoimmune diabetes and improved life expectancy by a soluble pHLA-DR4 chimera in a newly-humanized NOD/DR4/B7 mouse

Humanized HLA-DR4.RagKO.IL2RγcKO.NOD (DRAG) mice sustain the complex vertebrate life cycle of Plasmodium falciparum malaria

Down-regulation of autoreactive T-cells by HMG CoA reductase inhibitors

Differential partitioning and trafficking of GM gangliosides and cholesterol-rich lipid rafts in thymic and splenic CD4 T cells

Differential effect of CD4+ Foxp3+ T-regulatory cells on the B and T helper cell responses to influenza virus vaccination

Soluble, dimeric HLA DR4‐peptide chimeras: An approach for detection and immunoregulation of human type‐1 diabetes

Antigen-specific downregulation of T cells by doxorubicin delivered through a recombinant MHC II-peptide chimera

RNA degradation precedes DNA cleavage in autoreactive CD4 T cells suppressed by calicheamicin γ1

Reversal of type 1 diabetes by a new MHC II‐peptide chimera: “Single‐epitope‐mediated suppression” to stabilize a polyclonal autoimmune T‐cell process

Efficacy of clonal deletion vs. anergy of self-reactive CD4 T-cells for the prevention and reversal of autoimmune diabetes

Enzymatically mediated engineering of multivalent MHC class II–peptide chimeras

Analysis of lipid rafts in T cells

CD28 Signaling in T Regulatory Precursors Requires p56lck and Rafts Integrity to Stabilize the Foxp3 Message

A peptide-major histocompatibility complex II chimera favors survival of pancreatic beta-islets grafted in type 1 diabetic mice

Immunopotency of a viral peptide assembled on the carbohydrate moieties of self immunoglobulins

Antineoplastic efficacy of doxorubicin enzymatically assembled on galactose residues of a monoclonal antibody specific for the carcinoembryonic antigen

Role of lipid rafts in T cells

Thymic Development of CD4+25hi Foxp3+ T-Regulatory Cells Echoes their Suppressogenic Capacity in Periphery

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