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Reduced secretion of LCN2 (lipocalin 2) from reactive astrocytes through autophagic and proteasomal regulation alleviates inflammatory stress and neuronal damage

Autophagy, 2023-08, Vol.19 (8), p.2296-2317

2023

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Lipocalin-2 Promotes Pancreatic Ductal Adenocarcinoma by Regulating Inflammation in the Tumor Microenvironment

Cancer research (Chicago, Ill.), 2017-05, Vol.77 (10), p.2647-2660

2017

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Tumour stroma-derived lipocalin-2 promotes breast cancer metastasis

The Journal of pathology, 2016-07, Vol.239 (3), p.274-285

2016

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Lipocalin‐2 (NGAL) Attenuates Autophagy to Exacerbate Cardiac Apoptosis Induced by Myocardial Ischemia

Journal of cellular physiology, 2017-08, Vol.232 (8), p.2125-2134

2017

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Ultra-Early Cerebral Thrombosis Formation After Experimental Subarachnoid Hemorrhage Detected on T2 Magnetic Resonance Imaging

Stroke (1970), 2021-03, Vol.52 (3), p.1033-1042

2021

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Lipocalin-2 deficiency or blockade protects against aortic abdominal aneurysm development in mice

Cardiovascular research, 2016-08, Vol.111 (3), p.262-273

2016

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Lipocalin-2 inhibition alleviates neural injury by microglia ferroptosis suppression after experimental intracerebral hemorrhage in mice via enhancing ferritin light chain expression

Biochimica et biophysica acta. Molecular basis of disease, 2024-10, Vol.1870 (7), p.167435, Article 167435

2024

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PGC‐1α deficiency causes spontaneous kidney inflammation and increases the severity of nephrotoxic AKI

The Journal of pathology, 2019-09, Vol.249 (1), p.65-78

2019

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NGAL as a Potential Target in Tumor Microenvironment

International journal of molecular sciences, 2021-11, Vol.22 (22), p.12333

2021

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Neutrophil Gelatinase-Associated Lipocalin From Macrophages Plays a Critical Role in Renal Fibrosis Via the CCL5 (Chemokine Ligand 5)-Th2 Cells-IL4 (Interleukin 4) Pathway

Hypertension (Dallas, Tex. 1979), 2022-02, Vol.79 (2), p.352-364

2022

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Biological Functions and Therapeutic Potential of Lipocalin 2 in Cancer

International journal of molecular sciences, 2020-06, Vol.21 (12), p.4365

2020

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Nicotine promotes breast cancer metastasis by stimulating N2 neutrophils and generating pre-metastatic niche in lung

Nature communications, 2021-01, Vol.12 (1), p.474-18, Article 474

2021

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Lipocalin 2 mediates appetite suppression during pancreatic cancer cachexia

Nature communications, 2021-04, Vol.12 (1), p.2057-15, Article 2057

2021

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Lipocalin-2 as a prognostic marker in patients with acute exacerbation of idiopathic pulmonary fibrosis

Respiratory research, 2024-05, Vol.25 (1), p.195-195, Article 195

2024

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Deceased donor kidney function and branched chain amino acid metabolism during ex vivo normothermic perfusion

Kidney international, 2024-10, Vol.106 (4), p.712-722

2024

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Neutrophil-derived lipocalin-2 in adult-onset Still’s disease: a novel biomarker of disease activity and liver damage

Rheumatology (Oxford, England), 2021-01, Vol.60 (1), p.304-315

2021

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Activating the AKT2–nuclear factor‐κB–lipocalin‐2 axis elicits an inflammatory response in age‐related macular degeneration

The Journal of pathology, 2017-04, Vol.241 (5), p.583-588

2017

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Bacterial Siderophores Hijack Neutrophil Functions

The Journal of immunology (1950), 2017-06, Vol.198 (11), p.4293-4303

2017

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Vitamin D promotes the cisplatin sensitivity of oral squamous cell carcinoma by inhibiting LCN2-modulated NF-κB pathway activation through RPS3

Cell death & disease, 2019-12, Vol.10 (12), p.936, Article 936

2019

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The role of LCN2 in exacerbating ferroptosis levels in acute ischemic stroke injury

Biochemical and biophysical research communications, 2024-11, Vol.733, p.150452, Article 150452

2024

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CD4 + T Cell-Derived NGAL Modifies the Outcome of Ischemic Acute Kidney Injury

The Journal of immunology (1950), 2020-02, Vol.204 (3), p.586-595

2020

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Lipocalin-2 Is a Key Regulator of Neuroinflammation in Secondary Traumatic and Ischemic Brain Injury

Neurotherapeutics, 2023-04, Vol.20 (3), p.803-821

2023

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Glioma-derived exosomes hijack the blood–brain barrier to facilitate nanocapsule delivery via LCN2

Journal of controlled release, 2022-05, Vol.345, p.537-548

2022

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Photobiomodulation inhibits the activation of neurotoxic microglia and astrocytes by inhibiting Lcn2/JAK2-STAT3 crosstalk after spinal cord injury in male rats

Journal of neuroinflammation, 2021-11, Vol.18 (1), p.256-20, Article 256

2021

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A novel transgenic mouse model highlights molecular disruptions involved in the pathogenesis of Dent disease 1

Gene, 2024-11, Vol.928, p.148766, Article 148766

2024

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Reduced secretion of LCN2 (lipocalin 2) from reactive astrocytes through autophagic and proteasomal regulation alleviates inflammatory stress and neuronal damage

Lipocalin-2 Promotes Pancreatic Ductal Adenocarcinoma by Regulating Inflammation in the Tumor Microenvironment

Tumour stroma-derived lipocalin-2 promotes breast cancer metastasis

Lipocalin‐2 (NGAL) Attenuates Autophagy to Exacerbate Cardiac Apoptosis Induced by Myocardial Ischemia

Ultra-Early Cerebral Thrombosis Formation After Experimental Subarachnoid Hemorrhage Detected on T2 Magnetic Resonance Imaging

Lipocalin-2 deficiency or blockade protects against aortic abdominal aneurysm development in mice

Lipocalin-2 inhibition alleviates neural injury by microglia ferroptosis suppression after experimental intracerebral hemorrhage in mice via enhancing ferritin light chain expression

PGC‐1α deficiency causes spontaneous kidney inflammation and increases the severity of nephrotoxic AKI

NGAL as a Potential Target in Tumor Microenvironment

Neutrophil Gelatinase-Associated Lipocalin From Macrophages Plays a Critical Role in Renal Fibrosis Via the CCL5 (Chemokine Ligand 5)-Th2 Cells-IL4 (Interleukin 4) Pathway

Biological Functions and Therapeutic Potential of Lipocalin 2 in Cancer

Nicotine promotes breast cancer metastasis by stimulating N2 neutrophils and generating pre-metastatic niche in lung

Lipocalin 2 mediates appetite suppression during pancreatic cancer cachexia

Lipocalin-2 as a prognostic marker in patients with acute exacerbation of idiopathic pulmonary fibrosis

Deceased donor kidney function and branched chain amino acid metabolism during ex vivo normothermic perfusion

Neutrophil-derived lipocalin-2 in adult-onset Still’s disease: a novel biomarker of disease activity and liver damage

Activating the AKT2–nuclear factor‐κB–lipocalin‐2 axis elicits an inflammatory response in age‐related macular degeneration

Bacterial Siderophores Hijack Neutrophil Functions

Vitamin D promotes the cisplatin sensitivity of oral squamous cell carcinoma by inhibiting LCN2-modulated NF-κB pathway activation through RPS3

The role of LCN2 in exacerbating ferroptosis levels in acute ischemic stroke injury

CD4 + T Cell-Derived NGAL Modifies the Outcome of Ischemic Acute Kidney Injury

Lipocalin-2 Is a Key Regulator of Neuroinflammation in Secondary Traumatic and Ischemic Brain Injury

Glioma-derived exosomes hijack the blood–brain barrier to facilitate nanocapsule delivery via LCN2

Photobiomodulation inhibits the activation of neurotoxic microglia and astrocytes by inhibiting Lcn2/JAK2-STAT3 crosstalk after spinal cord injury in male rats

A novel transgenic mouse model highlights molecular disruptions involved in the pathogenesis of Dent disease 1

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