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Mechanisms of Autophagy Initiation

Annual review of biochemistry, 2017-06, Vol.86 (1), p.225-244

2017

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Phosphatidylinositol 3‑Kinase (PI3K) and Phosphatidylinositol 3‑Kinase-Related Kinase (PIKK) Inhibitors: Importance of the Morpholine Ring

Journal of medicinal chemistry, 2015-01, Vol.58 (1), p.41-71

2015

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Natural products targeting the PI3K-Akt-mTOR signaling pathway in cancer: A novel therapeutic strategy

Seminars in cancer biology, 2022-05, Vol.80, p.1-17

2022

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Inhibition of the PI3K/AKT Pathway Reduces Tumor Necrosis Factor-Alpha Production in the Cellular Response to Wear Particles In Vitro

Artificial organs, 2013-03, Vol.37 (3), p.298-307

2013

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The PI3K AKT Pathway as a Target for Cancer Treatment

Annual review of medicine, 2016-01, Vol.67 (1), p.11-28

2016

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Activation of phosphatidylinositol 3-kinase/Akt signaling pathway mediates acquired resistance to sorafenib in hepatocellular carcinoma cells

The Journal of pharmacology and experimental therapeutics, 2011-04, Vol.337 (1), p.155-161

2011

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Phosphatidylinositol 3-kinase and COPII generate LC3 lipidation vesicles from the ER-Golgi intermediate compartment

eLife, 2014-11, Vol.3, p.e04135-e04135

2014

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Dysregulated phosphoinositide 3-kinase signaling in microglia: shaping chronic neuroinflammation

Journal of neuroinflammation, 2021-11, Vol.18 (1), p.276-276, Article 276

2021

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Cellular Entry of Human Papillomavirus Type 16 Involves Activation of the Phosphatidylinositol 3-Kinase/Akt/mTOR Pathway and Inhibition of Autophagy

Journal of Virology, 2013-03, Vol.87 (5), p.2508-2517

2013

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Signaling through the Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Axis Is Responsible for Aerobic Glycolysis mediated by Glucose Transporter in Epidermal Growth Factor Receptor (EGFR)-mutated Lung Adenocarcinoma

The Journal of biological chemistry, 2015-07, Vol.290 (28), p.17495-17504

2015

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Antigen receptor–mediated changes in glucose metabolism in B lymphocytes: role of phosphatidylinositol 3-kinase signaling in the glycolytic control of growth

Blood, 2006-06, Vol.107 (11), p.4458-4465

2006

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Ultrafine particulate matter impairs mitochondrial redox homeostasis and activates phosphatidylinositol 3-kinase mediated DNA damage responses in lymphocytes

Environmental pollution (1987), 2018-03, Vol.234, p.406-419

2018

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Autophagy-related (ATG) 11, ATG9 and the phosphatidylinositol 3-kinase control ATG2-mediated formation of autophagosomes in Arabidopsis

Plant cell reports, 2018-04, Vol.37 (4), p.653-664

2018

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The PI3K-AKT-mTOR Pathway and Prostate Cancer: At the Crossroads of AR, MAPK, and WNT Signaling

International journal of molecular sciences, 2020-06, Vol.21 (12), p.4507

2020

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Targeting the Phosphatidylinositol 3‐Kinase Signaling Pathway in Breast Cancer

The oncologist (Dayton, Ohio), 2011-01, Vol.16 (4), p.404-414

2011

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Insulin Enhances Gene Expression of Midnolin , a Novel Genetic Risk Factor for Parkinson's Disease, via Extracellular Signal-Regulated Kinase, Phosphoinositide 3-Kinase and Multiple Transcription Factors in SH-SY5Y Cells

The Journal of pharmacology and experimental therapeutics, 2022-05, Vol.381 (2), p.68-78

2022

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Discovery of selective phosphatidylinositol 3-kinase inhibitors to treat hematological malignancies

Drug discovery today, 2015-08, Vol.20 (8), p.988-994

2015

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A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria

Nature (London), 2015-04, Vol.520 (7549), p.683-687

2015

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Growth Factor Receptor Signaling Inhibition Prevents SARS-CoV-2 Replication

Molecular cell, 2020-10, Vol.80 (1), p.164-174.e4

2020

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Luminal B breast cancer: molecular characterization, clinical management, and future perspectives

Journal of clinical oncology, 2014-09, Vol.32 (25), p.2794-2803

2014

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Fine particulate matter leads to reproductive impairment in male rats by overexpressing phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) signaling pathway

Toxicology letters, 2015-09, Vol.237 (3), p.181-190

2015

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The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation

Trends in biochemical sciences (Amsterdam. Regular ed.), 2011-06, Vol.36 (6), p.320-328

2011

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Quercetin inhibited epithelial mesenchymal transition in diabetic rats, high-glucose-cultured lens, and SRA01/04 cells through transforming growth factor-β2/phosphoinositide 3-kinase/Akt pathway

Molecular and cellular endocrinology, 2017-09, Vol.452, p.44-56

2017

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Identification and characterization of NVP-BKM120, an orally available pan-class I PI3-kinase inhibitor

Molecular cancer therapeutics, 2012-02, Vol.11 (2), p.317-328

2012

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Targeting the PI3K/AKT/mTOR pathway in triple-negative breast cancer: a review

Breast cancer research and treatment, 2018-06, Vol.169 (3), p.397-406

2018

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Mechanisms of Autophagy Initiation

Phosphatidylinositol 3‑Kinase (PI3K) and Phosphatidylinositol 3‑Kinase-Related Kinase (PIKK) Inhibitors: Importance of the Morpholine Ring

Natural products targeting the PI3K-Akt-mTOR signaling pathway in cancer: A novel therapeutic strategy

Inhibition of the PI3K/AKT Pathway Reduces Tumor Necrosis Factor-Alpha Production in the Cellular Response to Wear Particles In Vitro

The PI3K AKT Pathway as a Target for Cancer Treatment

Activation of phosphatidylinositol 3-kinase/Akt signaling pathway mediates acquired resistance to sorafenib in hepatocellular carcinoma cells

Phosphatidylinositol 3-kinase and COPII generate LC3 lipidation vesicles from the ER-Golgi intermediate compartment

Dysregulated phosphoinositide 3-kinase signaling in microglia: shaping chronic neuroinflammation

Cellular Entry of Human Papillomavirus Type 16 Involves Activation of the Phosphatidylinositol 3-Kinase/Akt/mTOR Pathway and Inhibition of Autophagy

Signaling through the Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Axis Is Responsible for Aerobic Glycolysis mediated by Glucose Transporter in Epidermal Growth Factor Receptor (EGFR)-mutated Lung Adenocarcinoma

Antigen receptor–mediated changes in glucose metabolism in B lymphocytes: role of phosphatidylinositol 3-kinase signaling in the glycolytic control of growth

Ultrafine particulate matter impairs mitochondrial redox homeostasis and activates phosphatidylinositol 3-kinase mediated DNA damage responses in lymphocytes

Autophagy-related (ATG) 11, ATG9 and the phosphatidylinositol 3-kinase control ATG2-mediated formation of autophagosomes in Arabidopsis

The PI3K-AKT-mTOR Pathway and Prostate Cancer: At the Crossroads of AR, MAPK, and WNT Signaling

Targeting the Phosphatidylinositol 3‐Kinase Signaling Pathway in Breast Cancer

Insulin Enhances Gene Expression of Midnolin , a Novel Genetic Risk Factor for Parkinson's Disease, via Extracellular Signal-Regulated Kinase, Phosphoinositide 3-Kinase and Multiple Transcription Factors in SH-SY5Y Cells

Discovery of selective phosphatidylinositol 3-kinase inhibitors to treat hematological malignancies

A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria

Growth Factor Receptor Signaling Inhibition Prevents SARS-CoV-2 Replication

Luminal B breast cancer: molecular characterization, clinical management, and future perspectives

Fine particulate matter leads to reproductive impairment in male rats by overexpressing phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) signaling pathway

The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation

Quercetin inhibited epithelial mesenchymal transition in diabetic rats, high-glucose-cultured lens, and SRA01/04 cells through transforming growth factor-β2/phosphoinositide 3-kinase/Akt pathway

Identification and characterization of NVP-BKM120, an orally available pan-class I PI3-kinase inhibitor

Targeting the PI3K/AKT/mTOR pathway in triple-negative breast cancer: a review

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