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Diabetes clinical trials: helped or hindered by the current shift in regulatory requirements?

European heart journal, 2012-05, Vol.33 (9), p.1049-1057

2012

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Outcomes of Combined Cardiovascular Risk Factor Management Strategies in Type 2 Diabetes: The ACCORD Randomized Trial

Diabetes care, 2014-06, Vol.37 (6), p.1721-1728

2014

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A Randomized Trial of Intensive versus Standard Blood-Pressure Control

The New England journal of medicine, 2015-11, Vol.373 (22), p.2103-2116

2015

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Contributors to the Excess Stroke Mortality in Rural Areas in the United States

Stroke (1970), 2017-07, Vol.48 (7), p.1773-1778

2017

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Treatment-resistant hypertension and the incidence of cardiovascular disease and end-stage renal disease: results from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)

Hypertension (Dallas, Tex. 1979), 2014-11, Vol.64 (5), p.1012-1021

2014

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Blood pressure and mortality in U.S. veterans with chronic kidney disease: a cohort study

Annals of internal medicine, 2013-08, Vol.159 (4), p.233

2013

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HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials

The Lancet (British edition), 2015-01, Vol.385 (9965), p.351-361

2015

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The predominant PAR4 variant in individuals of African ancestry worsens murine and human stroke outcomes

The Journal of clinical investigation, 2023-09, Vol.133 (18), p.1-18

2023

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Association of orthostatic hypertension with mortality in the Systolic Hypertension in the Elderly Program

Journal of human hypertension, 2019-10, Vol.33 (10), p.735-740

2019

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Anticoagulant interventions in hospitalized patients with COVID‐19: A scoping review of randomized controlled trials and call for international collaboration

Journal of thrombosis and haemostasis, 2020-11, Vol.18 (11), p.2958-2967

2020

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The Benefits of Intensive Versus Standard Blood Pressure Treatment According to Fine Particulate Matter Air Pollution Exposure: A Post Hoc Analysis of SPRINT

Hypertension (Dallas, Tex. 1979), 2021-03, Vol.77 (3), p.813-822

2021

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Blood Pressure Control and the Association With Diabetes Mellitus Incidence: Results From SPRINT Randomized Trial

Hypertension (Dallas, Tex. 1979), 2020-02, Vol.75 (2), p.331-338

2020

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Nine-Year Effects of 3.7 Years of Intensive Glycemic Control on Cardiovascular Outcomes

Diabetes care, 2016-05, Vol.39 (5), p.701-708

2016

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Depressive symptoms and risks of coronary heart disease and mortality in elderly Americans

Circulation (New York, N.Y.), 2000-10, Vol.102 (15), p.1773-1779

2000

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Rural/urban differences in the prevalence of stroke risk factors: A cross‐sectional analysis from the REGARDS study

The Journal of rural health, 2022-06, Vol.38 (3), p.668-673

2022

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Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data

BMJ (British Medical Journal), 2011-02, Vol.342 (7794), p.425-425

International edition, 2011

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The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report

JAMA : the journal of the American Medical Association, 2003-05, Vol.289 (19), p.2560

2003

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Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)

JAMA : the journal of the American Medical Association, 2002-12, Vol.288 (23), p.2981

ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group. The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial

2002

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Sex-Specific Associations of Cardiovascular Risk Factors and Biomarkers With Incident Heart Failure

Journal of the American College of Cardiology, 2020-09, Vol.76 (12), p.1455-1465

2020

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Glycated hemoglobin measurement and prediction of cardiovascular disease

JAMA : the journal of the American Medical Association, 2014-03, Vol.311 (12), p.1225

2014

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Differences in Natriuretic Peptide Levels by Race/Ethnicity (From the Multi-Ethnic Study of Atherosclerosis)

The American journal of cardiology, 2017-09, Vol.120 (6), p.1008-1015

2017

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Lipid-related markers and cardiovascular disease prediction

JAMA : the journal of the American Medical Association, 2012-06, Vol.307 (23), p.2499

2012

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Lipoprotein-associated phospholipase A(2) and risk of coronary disease, stroke, and mortality: collaborative analysis of 32 prospective studies

The Lancet (British edition), 2010-05, Vol.375 (9725), p.1536-1544

2010

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Major outcomes in moderately hypercholesterolemic, hypertensive patients randomized to pravastatin vs usual care: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT-LLT)

JAMA : the journal of the American Medical Association, 2002-12, Vol.288 (23), p.2998

ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group. The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial

2002

Volltextzugriff (PDF)

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Diabetes clinical trials: helped or hindered by the current shift in regulatory requirements?

Outcomes of Combined Cardiovascular Risk Factor Management Strategies in Type 2 Diabetes: The ACCORD Randomized Trial

A Randomized Trial of Intensive versus Standard Blood-Pressure Control

Contributors to the Excess Stroke Mortality in Rural Areas in the United States

Treatment-resistant hypertension and the incidence of cardiovascular disease and end-stage renal disease: results from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)

Blood pressure and mortality in U.S. veterans with chronic kidney disease: a cohort study

HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials

The predominant PAR4 variant in individuals of African ancestry worsens murine and human stroke outcomes

Association of orthostatic hypertension with mortality in the Systolic Hypertension in the Elderly Program

Anticoagulant interventions in hospitalized patients with COVID‐19: A scoping review of randomized controlled trials and call for international collaboration

The Benefits of Intensive Versus Standard Blood Pressure Treatment According to Fine Particulate Matter Air Pollution Exposure: A Post Hoc Analysis of SPRINT

Blood Pressure Control and the Association With Diabetes Mellitus Incidence: Results From SPRINT Randomized Trial

Nine-Year Effects of 3.7 Years of Intensive Glycemic Control on Cardiovascular Outcomes

Depressive symptoms and risks of coronary heart disease and mortality in elderly Americans

Rural/urban differences in the prevalence of stroke risk factors: A cross‐sectional analysis from the REGARDS study

Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data

The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report

Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)

Sex-Specific Associations of Cardiovascular Risk Factors and Biomarkers With Incident Heart Failure

Glycated hemoglobin measurement and prediction of cardiovascular disease

Differences in Natriuretic Peptide Levels by Race/Ethnicity (From the Multi-Ethnic Study of Atherosclerosis)

Lipid-related markers and cardiovascular disease prediction

Association of Traditional Cardiovascular Risk Factors with Venous Thromboembolism: An Individual Participant Data Meta-analysis of Prospective Studies

Lipoprotein-associated phospholipase A(2) and risk of coronary disease, stroke, and mortality: collaborative analysis of 32 prospective studies

Major outcomes in moderately hypercholesterolemic, hypertensive patients randomized to pravastatin vs usual care: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT-LLT)

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