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Lysosomal impairment in Parkinson's disease

Movement disorders, 2013-06, Vol.28 (6), p.725-732

2013

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Coordination of mitochondrial and lysosomal homeostasis mitigates inflammation and muscle atrophy during aging

Aging cell, 2022-04, Vol.21 (4), p.e13583-n/a

2022

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Investigating the impact of physical activity on mitochondrial function in Parkinson’s disease (PARKEX): Study protocol for A randomized controlled clinical trial

PloS one, 2023-11, Vol.18 (11), p.e0293774-e0293774

2023

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Protein degradation, aggregation, and misfolding

Movement disorders, 2010, Vol.25 (S1), p.S49-S54

2010

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Brain region- and age-dependent dysregulation of p62 and NBR1 in a mouse model of Huntington's disease

Neurobiology of disease, 2013-04, Vol.52, p.219-228

2013

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Autophagy maintains stemness by preventing senescence

Nature (London), 2016-01, Vol.529 (7584), p.37-42

2016

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Autophagy and neurodegeneration: when the cleaning crew goes on strike

Lancet neurology, 2007-04, Vol.6 (4), p.352-361

2007

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Brain tyrosinase overexpression implicates age-dependent neuromelanin production in Parkinson's disease pathogenesis

Nature communications, 2019-03, Vol.10 (1), p.973-973, Article 973

2019

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Impaired proteasome activity and neurodegeneration with brain iron accumulation in FBXO7 defect

Annals of clinical and translational neurology, 2020-08, Vol.7 (8), p.1436-1442

2020

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The Emerging Role of the Lysosome in Parkinson's Disease

Cells (Basel, Switzerland), 2020-11, Vol.9 (11), p.2399

2020

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Clusterin deficiency is associated with a lack of response to teriflunomide in multiple sclerosis

Clinical and translational medicine, 2024-04, Vol.14 (4), p.e1654-n/a

2024

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Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease

Nature neuroscience, 2010-05, Vol.13 (5), p.567-576

2010

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Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration

Proceedings of the National Academy of Sciences - PNAS, 2012-06, Vol.109 (24), p.9611-9616

2012

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Constitutive upregulation of chaperone-mediated autophagy in Huntington's disease

The Journal of neuroscience, 2011-12, Vol.31 (50), p.18492-18505

2011

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A photoconvertible fluorescent reporter to track chaperone-mediated autophagy

Nature communications, 2011-07, Vol.2 (1), p.386-386, Article 386

2011

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The Consequences of GBA Deficiency in the Autophagy-Lysosome System in Parkinson's Disease Associated with GBA

Cells (Basel, Switzerland), 2023-01, Vol.12 (1), p.191

2023

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Novel Therapeutic Approach to Induce Autophagy in a Drosophila Model for Huntington's Disease

Cells (Basel, Switzerland), 2020-02, Vol.9 (2), p.495

Martinez-Vicente, Marta

2020

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Sex-dependent calcium hyperactivity due to lysosomal-related dysfunction in astrocytes from APOE4 versus APOE3 gene targeted replacement mice

Molecular neurodegeneration, 2020-06, Vol.15 (1), p.1-35, Article 35

2020

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Lysosomal dysfunction in Parkinson disease: ATP13A2 gets into the groove

Autophagy, 2012-09, Vol.8 (9), p.1389-1391

2012

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Lysosomal lipid alterations caused by glucocerebrosidase deficiency promote lysosomal dysfunction, chaperone-mediated-autophagy deficiency, and alpha-synuclein pathology

NPJ Parkinson's Disease, 2022-10, Vol.8 (1), p.126-126, Article 126

2022

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Synergy and antagonism of macroautophagy and chaperone-mediated autophagy in a cell model of pathological tau aggregation

Autophagy, 2010-01, Vol.6 (1), p.182-183

2010

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Fighting neurodegeneration with rapamycin: mechanistic insights

Nature reviews. Neuroscience, 2011-08, Vol.12 (8), p.437-452

2011

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Neuronal Mitophagy in Neurodegenerative Diseases

Frontiers in molecular neuroscience, 2017-03, Vol.10, p.64-64

Martinez-Vicente, Marta

2017

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Capacidad predictiva de variables asociadas al funcionamiento ejecutivo en el perfil estudiantil: aportaciones a la neurociencia educativa

Revista complutense de educación, 2023-04, Vol.34 (2), p.301-312

2023

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Autophagy in neurodegenerative diseases: From pathogenic dysfunction to therapeutic modulation

Seminars in cell & developmental biology, 2015-04, Vol.40, p.115-126

Martinez-Vicente, Marta

2015

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Lysosomal impairment in Parkinson's disease

Coordination of mitochondrial and lysosomal homeostasis mitigates inflammation and muscle atrophy during aging

Investigating the impact of physical activity on mitochondrial function in Parkinson’s disease (PARKEX): Study protocol for A randomized controlled clinical trial

Protein degradation, aggregation, and misfolding

Brain region- and age-dependent dysregulation of p62 and NBR1 in a mouse model of Huntington's disease

Autophagy maintains stemness by preventing senescence

Autophagy and neurodegeneration: when the cleaning crew goes on strike

Brain tyrosinase overexpression implicates age-dependent neuromelanin production in Parkinson's disease pathogenesis

Impaired proteasome activity and neurodegeneration with brain iron accumulation in FBXO7 defect

The Emerging Role of the Lysosome in Parkinson's Disease

Clusterin deficiency is associated with a lack of response to teriflunomide in multiple sclerosis

Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease

Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration

Constitutive upregulation of chaperone-mediated autophagy in Huntington's disease

A photoconvertible fluorescent reporter to track chaperone-mediated autophagy

The Consequences of GBA Deficiency in the Autophagy-Lysosome System in Parkinson's Disease Associated with GBA

Novel Therapeutic Approach to Induce Autophagy in a Drosophila Model for Huntington's Disease

Sex-dependent calcium hyperactivity due to lysosomal-related dysfunction in astrocytes from APOE4 versus APOE3 gene targeted replacement mice

Lysosomal dysfunction in Parkinson disease: ATP13A2 gets into the groove

Lysosomal lipid alterations caused by glucocerebrosidase deficiency promote lysosomal dysfunction, chaperone-mediated-autophagy deficiency, and alpha-synuclein pathology

Synergy and antagonism of macroautophagy and chaperone-mediated autophagy in a cell model of pathological tau aggregation

Fighting neurodegeneration with rapamycin: mechanistic insights

Neuronal Mitophagy in Neurodegenerative Diseases

Capacidad predictiva de variables asociadas al funcionamiento ejecutivo en el perfil estudiantil: aportaciones a la neurociencia educativa

Autophagy in neurodegenerative diseases: From pathogenic dysfunction to therapeutic modulation

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