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Substrate processing by the Cdc48 ATPase complex is initiated by ubiquitin unfolding

Science (American Association for the Advancement of Science), 2019-08, Vol.365 (6452)

2019

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Developments in Hydrogen/Deuterium Exchange Mass Spectrometry

Analytical chemistry (Washington), 2021-01, Vol.93 (1), p.567-582

2021

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Inhibition of Pro-Apoptotic BAX by a Noncanonical Interaction Mechanism

Molecular cell, 2015-03, Vol.57 (5), p.873-886

2015

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Hydrogen exchange mass spectrometry for the analysis of protein dynamics

Mass spectrometry reviews, 2006-01, Vol.25 (1), p.158-170

2006

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Translocation of polyubiquitinated protein substrates by the hexameric Cdc48 ATPase

Molecular cell, 2022-02, Vol.82 (3), p.570-584.e8

2022

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Structure, function, and inhibitor targeting of HIV-1 Nef-effector kinase complexes

The Journal of biological chemistry, 2020-10, Vol.295 (44), p.15158-15171

2020

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High-Speed and High-Resolution UPLC Separation at Zero Degrees Celsius

Analytical chemistry (Washington), 2008-09, Vol.80 (17), p.6815-6820

2008

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Structural Stability and Local Dynamics in Disease-Causing Mutants of Human Apolipoprotein A-I: What Makes the Protein Amyloidogenic?

Journal of molecular biology, 2016-01, Vol.428 (2), p.449-462

2016

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The conformational stability of pro-apoptotic BAX is dictated by discrete residues of the protein core

Nature communications, 2021-08, Vol.12 (1), p.4932-4932, Article 4932

2021

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Structural Basis for Lipid Binding and Function by an Evolutionarily Conserved Protein, Serum Amyloid A

Journal of molecular biology, 2020-03, Vol.432 (7), p.1978-1995

2020

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Differential sensitivity of Src-family kinases to activation by SH3 domain displacement

PloS one, 2014-08, Vol.9 (8), p.e105629-e105629

2014

Volltextzugriff (PDF)

Differential impact of BTK active site inhibitors on the conformational state of full-length BTK

eLife, 2020-11, Vol.9

2020

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Dynamic Allostery Mediated by a Conserved Tryptophan in the Tec Family Kinases

PLoS computational biology, 2016-03, Vol.12 (3), p.e1004826-e1004826

2016

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Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states

eLife, 2024-01, Vol.12

2024

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Structural basis for defective membrane targeting of mutant enzyme in human VLCAD deficiency

Nature communications, 2022-06, Vol.13 (1), p.3669-3669, Article 3669

2022

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Site-Dependent Cysteine Lipidation Potentiates the Activation of Proapoptotic BAX

Cell reports (Cambridge), 2020-03, Vol.30 (10), p.3229-3239.e6

2020

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Hydrocarbon-Stitched Peptide Agonists of Glucagon-Like Peptide-1 Receptor

ACS chemical biology, 2020-06, Vol.15 (6), p.1340-1348

2020

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Evidence for Increased Exposure of the Notch1 Metalloprotease Cleavage Site upon Conversion to an Activated Conformation

Structure (London), 2011-04, Vol.19 (4), p.546-554

2011

Volltextzugriff (PDF)

Identification and Characterization of EX1 Kinetics in H/D Exchange Mass Spectrometry by Peak Width Analysis

Journal of the American Society for Mass Spectrometry, 2006-11, Vol.17 (11), p.1498-1509

2006

Volltextzugriff (PDF)

Design of stapled antimicrobial peptides that are stable, nontoxic and kill antibiotic-resistant bacteria in mice

Nature biotechnology, 2019-10, Vol.37 (10), p.1186-1197

2019

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Conformational Locking upon Cooperative Assembly of Notch Transcription Complexes

Structure (London), 2012-02, Vol.20 (2), p.340-349

2012

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Simple and Fast Maximally Deuterated Control (maxD) Preparation for Hydrogen–Deuterium Exchange Mass Spectrometry Experiments

Analytical chemistry (Washington), 2022-07, Vol.94 (28), p.10142-10150

2022

Volltextzugriff (PDF)

Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments

Nature methods, 2019-07, Vol.16 (7), p.595

2019

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Increase the flow rate and improve hydrogen deuterium exchange mass spectrometry

Journal of Chromatography A, 2023-01, Vol.1689, p.463742-463742, Article 463742

2023

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Structure of the Cdc48 ATPase with its ubiquitin-binding cofactor Ufd1-Npl4

Nature structural & molecular biology, 2018-07, Vol.25 (7), p.616

2018

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Substrate processing by the Cdc48 ATPase complex is initiated by ubiquitin unfolding

Developments in Hydrogen/Deuterium Exchange Mass Spectrometry

Inhibition of Pro-Apoptotic BAX by a Noncanonical Interaction Mechanism

Hydrogen exchange mass spectrometry for the analysis of protein dynamics

Translocation of polyubiquitinated protein substrates by the hexameric Cdc48 ATPase

Structure, function, and inhibitor targeting of HIV-1 Nef-effector kinase complexes

High-Speed and High-Resolution UPLC Separation at Zero Degrees Celsius

Structural Stability and Local Dynamics in Disease-Causing Mutants of Human Apolipoprotein A-I: What Makes the Protein Amyloidogenic?

The conformational stability of pro-apoptotic BAX is dictated by discrete residues of the protein core

Structural Basis for Lipid Binding and Function by an Evolutionarily Conserved Protein, Serum Amyloid A

Differential sensitivity of Src-family kinases to activation by SH3 domain displacement

Differential impact of BTK active site inhibitors on the conformational state of full-length BTK

Dynamic Allostery Mediated by a Conserved Tryptophan in the Tec Family Kinases

Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states

Structural basis for defective membrane targeting of mutant enzyme in human VLCAD deficiency

Site-Dependent Cysteine Lipidation Potentiates the Activation of Proapoptotic BAX

Hydrocarbon-Stitched Peptide Agonists of Glucagon-Like Peptide-1 Receptor

Evidence for Increased Exposure of the Notch1 Metalloprotease Cleavage Site upon Conversion to an Activated Conformation

Identification and Characterization of EX1 Kinetics in H/D Exchange Mass Spectrometry by Peak Width Analysis

Design of stapled antimicrobial peptides that are stable, nontoxic and kill antibiotic-resistant bacteria in mice

Conformational Locking upon Cooperative Assembly of Notch Transcription Complexes

Simple and Fast Maximally Deuterated Control (maxD) Preparation for Hydrogen–Deuterium Exchange Mass Spectrometry Experiments

Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments

Increase the flow rate and improve hydrogen deuterium exchange mass spectrometry

Structure of the Cdc48 ATPase with its ubiquitin-binding cofactor Ufd1-Npl4

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