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An Evolutionary Conservation and Druggability Analysis of Enzymes Belonging to the Bacterial Shikimate Pathway

Antibiotics (Basel), 2022-05, Vol.11 (5), p.675

Frlan, Rok

2022

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6-Membered Pyrrololactams: An Overview of Current Synthetic Approaches to their Preparation

Current organic chemistry, 2018-01, Vol.22 (28), p.2780-2800

Frlan, Rok

2018

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Navigating the Chemical Space of ENR Inhibitors: A Comprehensive Analysis

Antibiotics (Basel), 2024-03, Vol.13 (3), p.252

2024

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The Synthesis of (2R)-Aziridine-2-carboxylic Acid Containing Dipeptides

Acta chimica Slovenica, 2022-06, Vol.69 (2), p.261-270

2022

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Inhibition of MurA Enzyme from Escherichia coli by Flavonoids and Their Synthetic Analogues

ACS omega, 2023-09, Vol.8 (36), p.33006-33016

2023

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Discovery of a fragment hit compound targeting D-Ala:D-Ala ligase of bacterial peptidoglycan biosynthesis

Journal of enzyme inhibition and medicinal chemistry, 2023-12, Vol.38 (1), p.387-397

2023

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Using Subcritical Water to Obtain Polyphenol-Rich Extracts with Antimicrobial Properties

Antibiotics (Basel), 2024-04, Vol.13 (4), p.334

2024

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A New Cell‐Based AI‐2‐Mediated Quorum Sensing Interference Assay in Screening of LsrK‐Targeted Inhibitors

Chembiochem : a European journal of chemical biology, 2020-07, Vol.21 (13), p.1918-1922

2020

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Efficient and Straightforward Syntheses of Two United States Pharmacopeia Sitagliptin Impurities: 3‑Desamino-2,3-dehydrositagliptin and 3‑Desamino-3,4-dehydrositagliptin

ACS omega, 2020-03, Vol.5 (10), p.5356-5364

2020

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Inhibition of MurA Enzyme from Escherichia coli and Staphylococcus aureus by Diterpenes from Lepechinia meyenii and Their Synthetic Analogs

Antibiotics (Basel), 2021-12, Vol.10 (12), p.1535

2021

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Recent Progress in Diaryl Ether Synthesis

Synthesis (Stuttgart), 2006-07, Vol.2006 (14), p.2271-2285

2006

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Synthesis of ethyl 3-(hydroxyphenoxy)benzyl butylphosphonates as potential antigen 85C inhibitors

Tetrahedron, 2007-10, Vol.63 (43), p.10698-10708

2007

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Evaluation of US 2016/0115161 A1: isoindoline compounds and methods of their use

Expert opinion on therapeutic patents, 2017-06, Vol.27 (6), p.637-641

2017

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Pyrimido[1,2-b]indazole derivatives: Selective inhibitors of human monoamine oxidase B with neuroprotective activity

European journal of medicinal chemistry, 2021-01, Vol.209, p.112911-112911, Article 112911

2021

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DNA-encoded library screening on two validated enzymes of the peptidoglycan biosynthetic pathway

Bioorganic & medicinal chemistry letters, 2022-10, Vol.73, p.128915-128915, Article 128915

2022

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Mur ligase F as a new target for the flavonoids quercitrin, myricetin, and (–)-epicatechin

Journal of computer-aided molecular design, 2023-12, Vol.37 (12), p.721-733

2023

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Mur ligases inhibitors with azastilbene scaffold: Expanding the structure–activity relationship

Bioorganic & medicinal chemistry letters, 2021-05, Vol.40, p.127966-127966, Article 127966

2021

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Identification of a Novel Structural Class of H V 1 Inhibitors by Structure-Based Virtual Screening

Journal of chemical information and modeling, 2024-06, Vol.64 (12), p.4850-4862

2024

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Effect of Preparation Temperature in Solvent Evaporation Process on Eudragit RS Microsphere Properties

Chemical and Pharmaceutical Bulletin, 2005, Vol.53(1), pp.143-146

2005

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Cobalt-Catalyzed Cross-Coupling of Grignards with Allylic and Vinylic Bromides: Use of Sarcosine as a Natural Ligand

Journal of organic chemistry, 2015-08, Vol.80 (15), p.7803-7809

2015

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Identification of a Novel Structural Class of HV1 Inhibitors by Structure-Based Virtual Screening

Journal of chemical information and modeling, 2024-06, Vol.64 (12), p.4850-4862

2024

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Nucleophilic Opening of an Epoxide by a Masked Glycine Anion Equivalent: A Route to C-Glycosyl Amino Acids

Synlett, 2016-06, Vol.27 (10), p.1551-1556

2016

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Indoles and 1-(3-(benzyloxy)benzyl)piperazines: Reversible and selective monoamine oxidase B inhibitors identified by screening an in-house compound library

Bioorganic chemistry, 2022-02, Vol.119, p.105581-105581, Article 105581

2022

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Fragment-Sized Thiazoles in Fragment-Based Drug Discovery Campaigns: Friend or Foe?

ACS medicinal chemistry letters, 2022-12, Vol.13 (12), p.1905-1910

2022

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D-Glucosamine in iron-catalysed cross-coupling reactions of Grignards with allylic and vinylic bromides: application to the synthesis of a key sitagliptin precursor

Applied organometallic chemistry, 2015-08, Vol.29 (8), p.528-535

2015

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An Evolutionary Conservation and Druggability Analysis of Enzymes Belonging to the Bacterial Shikimate Pathway

6-Membered Pyrrololactams: An Overview of Current Synthetic Approaches to their Preparation

Navigating the Chemical Space of ENR Inhibitors: A Comprehensive Analysis

The Synthesis of (2R)-Aziridine-2-carboxylic Acid Containing Dipeptides

Inhibition of MurA Enzyme from Escherichia coli by Flavonoids and Their Synthetic Analogues

Discovery of a fragment hit compound targeting D-Ala:D-Ala ligase of bacterial peptidoglycan biosynthesis

Using Subcritical Water to Obtain Polyphenol-Rich Extracts with Antimicrobial Properties

A New Cell‐Based AI‐2‐Mediated Quorum Sensing Interference Assay in Screening of LsrK‐Targeted Inhibitors

Efficient and Straightforward Syntheses of Two United States Pharmacopeia Sitagliptin Impurities: 3‑Desamino-2,3-dehydrositagliptin and 3‑Desamino-3,4-dehydrositagliptin

Inhibition of MurA Enzyme from Escherichia coli and Staphylococcus aureus by Diterpenes from Lepechinia meyenii and Their Synthetic Analogs

Recent Progress in Diaryl Ether Synthesis

Synthesis of ethyl 3-(hydroxyphenoxy)benzyl butylphosphonates as potential antigen 85C inhibitors

Evaluation of US 2016/0115161 A1: isoindoline compounds and methods of their use

Pyrimido[1,2-b]indazole derivatives: Selective inhibitors of human monoamine oxidase B with neuroprotective activity

DNA-encoded library screening on two validated enzymes of the peptidoglycan biosynthetic pathway

Mur ligase F as a new target for the flavonoids quercitrin, myricetin, and (–)-epicatechin

Mur ligases inhibitors with azastilbene scaffold: Expanding the structure–activity relationship

Identification of a Novel Structural Class of H V 1 Inhibitors by Structure-Based Virtual Screening

Effect of Preparation Temperature in Solvent Evaporation Process on Eudragit RS Microsphere Properties

Cobalt-Catalyzed Cross-Coupling of Grignards with Allylic and Vinylic Bromides: Use of Sarcosine as a Natural Ligand

Identification of a Novel Structural Class of HV1 Inhibitors by Structure-Based Virtual Screening

Nucleophilic Opening of an Epoxide by a Masked Glycine Anion Equivalent: A Route to C-Glycosyl Amino Acids

Indoles and 1-(3-(benzyloxy)benzyl)piperazines: Reversible and selective monoamine oxidase B inhibitors identified by screening an in-house compound library

Fragment-Sized Thiazoles in Fragment-Based Drug Discovery Campaigns: Friend or Foe?

D-Glucosamine in iron-catalysed cross-coupling reactions of Grignards with allylic and vinylic bromides: application to the synthesis of a key sitagliptin precursor

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