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Unexpected Need of the Epidermal Growth Factor Receptor Tyrosine Kinase Activity for Signaling by Intracellular Pattern Recognition Receptors of Nucleic Acids

Journal of interferon & cytokine research, 2023-05, Vol.43 (5), p.189-193

2023

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The antiviral action of the RIG-I induced pathway of apoptosis (RIPA) is enhanced by its ability to degrade Otulin, which deubiquitinates IRF3

Cell death and differentiation, 2022-03, Vol.29 (3), p.504-513

2022

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Innate Immune Responses to Herpesvirus Infection

Cells (Basel, Switzerland), 2021-08, Vol.10 (8), p.2122

2021

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EGFR‐mediated tyrosine phosphorylation of STING determines its trafficking route and cellular innate immunity functions

The EMBO journal, 2020-11, Vol.39 (22), p.e104106-n/a

2020

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RIG-I-like receptor-induced IRF3 mediated pathway of apoptosis (RIPA): a new antiviral pathway

Protein & Cell, 2017-03, Vol.8 (3), p.165-168

2017

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Ubiquitination of the Transcription Factor IRF-3 Activates RIPA, the Apoptotic Pathway that Protects Mice from Viral Pathogenesis

Immunity (Cambridge, Mass.), 2016-05, Vol.44 (5), p.1151-1161

2016

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EGFR kinase activity is required for TLR4 signaling and the septic shock response

EMBO reports, 2015-11, Vol.16 (11), p.1535-1547

2015

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Tyrosine phosphorylation in Toll-like receptor signaling

Cytokine & growth factor reviews, 2014-10, Vol.25 (5), p.533-541

2014

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dsRNA-activation of TLR3 and RLR signaling: gene induction-dependent and independent effects

Journal of interferon & cytokine research, 2014-06, Vol.34 (6), p.427-436

2014

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Meet the Terminator: The Phosphatase PP2A Puts Brakes on IRF-3 Activation

Molecular cell, 2014-04, Vol.54 (2), p.210-211

2014

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Philip I. Marcus, PhD (1927–2013)

Journal of interferon & cytokine research, 2014-01, Vol.34 (1), p.1-1

2014

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The ISG56/IFIT1 gene family

Journal of interferon & cytokine research, 2011-01, Vol.31 (1), p.71-78

2011

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IRF-3 and Bax: A deadly affair

Cell cycle (Georgetown, Tex.), 2010-07, Vol.9 (13), p.2479-2480

2010

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Viral apoptosis is induced by IRF-3-mediated activation of Bax

The EMBO journal, 2010-05, Vol.29 (10), p.1762-1773

2010

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Viral evasion of the interferon system

Journal of interferon & cytokine research, 2009-09, Vol.29 (9), p.475-476

2009

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Interferon-inducible protein, P56, inhibits HPV DNA replication by binding to the viral protein E1

The EMBO journal, 2008-12, Vol.27 (24), p.3311-3321

2008

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The role of PACT in mediating gene induction, PKR activation, and apoptosis in response to diverse stimuli

Journal of interferon & cytokine research, 2008-08, Vol.28 (8), p.469-476

2008

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Interferons at age 50: past, current and future impact on biomedicine

Nature reviews. Drug discovery, 2007-12, Vol.6 (12), p.975-990

2007

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A site on the influenza A virus NS1 protein mediates both inhibition of PKR activation and temporal regulation of viral RNA synthesis

Virology (New York, N.Y.), 2007-06, Vol.363 (1), p.236-243

2007

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Stat1 required for interferon-inducible but not constitutive responsiveness to extracellular dsRNA

Journal of interferon & cytokine research, 2007-05, Vol.27 (5), p.411-424

2007

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Binding of the influenza A virus NS1 protein to PKR mediates the inhibition of its activation by either PACT or double-stranded RNA

Virology (New York, N.Y.), 2006-05, Vol.349 (1), p.13-21

2006

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Hitching RIG to action

Nature immunology, 2005-11, Vol.6 (11), p.1074-1076

2005

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Induction and mode of action of the viral stress-inducible murine proteins, P56 and P54

Virology (New York, N.Y.), 2005-09, Vol.340 (1), p.116-124

2005

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Transcriptional signaling by double-stranded RNA: role of TLR3

Cytokine & growth factor reviews, 2005-02, Vol.16 (1), p.1-14

2005

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Novel roles of TLR3 tyrosine phosphorylation and PI3 kinase in double-stranded RNA signaling

Nature structural & molecular biology, 2004-11, Vol.11 (11), p.1060-1067

2004

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Unexpected Need of the Epidermal Growth Factor Receptor Tyrosine Kinase Activity for Signaling by Intracellular Pattern Recognition Receptors of Nucleic Acids

The antiviral action of the RIG-I induced pathway of apoptosis (RIPA) is enhanced by its ability to degrade Otulin, which deubiquitinates IRF3

Innate Immune Responses to Herpesvirus Infection

EGFR‐mediated tyrosine phosphorylation of STING determines its trafficking route and cellular innate immunity functions

RIG-I-like receptor-induced IRF3 mediated pathway of apoptosis (RIPA): a new antiviral pathway

Ubiquitination of the Transcription Factor IRF-3 Activates RIPA, the Apoptotic Pathway that Protects Mice from Viral Pathogenesis

EGFR kinase activity is required for TLR4 signaling and the septic shock response

Tyrosine phosphorylation in Toll-like receptor signaling

dsRNA-activation of TLR3 and RLR signaling: gene induction-dependent and independent effects

Meet the Terminator: The Phosphatase PP2A Puts Brakes on IRF-3 Activation

Philip I. Marcus, PhD (1927–2013)

The ISG56/IFIT1 gene family

IRF-3 and Bax: A deadly affair

Viral apoptosis is induced by IRF-3-mediated activation of Bax

Viral evasion of the interferon system

Interferon-inducible protein, P56, inhibits HPV DNA replication by binding to the viral protein E1

The role of PACT in mediating gene induction, PKR activation, and apoptosis in response to diverse stimuli

Interferons at age 50: past, current and future impact on biomedicine

A site on the influenza A virus NS1 protein mediates both inhibition of PKR activation and temporal regulation of viral RNA synthesis

Stat1 required for interferon-inducible but not constitutive responsiveness to extracellular dsRNA

Binding of the influenza A virus NS1 protein to PKR mediates the inhibition of its activation by either PACT or double-stranded RNA

Hitching RIG to action

Induction and mode of action of the viral stress-inducible murine proteins, P56 and P54

Transcriptional signaling by double-stranded RNA: role of TLR3

Novel roles of TLR3 tyrosine phosphorylation and PI3 kinase in double-stranded RNA signaling

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