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Allosteric modulation of the activity of the glucagon-like peptide-1 (GLP-1) metabolite GLP-1 9-36 amide at the GLP-1 receptor

PloS one, 2012-10, Vol.7 (10), p.e47936

2012

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Neuromedin U and its receptors: structure, function, and physiological roles

Pharmacological reviews, 2004-06, Vol.56 (2), p.231

2004

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Hazards of Using Masking Protocols When Performing Ligand Binding Assays: Lessons From the Sigma-1 and Sigma-2 Receptors

Frontiers in pharmacology, 2020-03, Vol.11, p.309-309

2020

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cAMP inhibits mammalian target of rapamycin complex-1 and -2 (mTORC1 and 2) by promoting complex dissociation and inhibiting mTOR kinase activity

Cellular signalling, 2011-12, Vol.23 (12), p.1927-1935

2011

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The role of phosphoinositide 3-kinases in neutrophil migration in 3D collagen gels

PloS one, 2015-02, Vol.10 (2), p.e0116250-e0116250

2015

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Mechanisms of cross-talk between G-protein-coupled receptors resulting in enhanced release of intracellular Ca2

Biochemical journal, 2003-09, Vol.374 (Pt 2), p.281-296

2003

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Endoplasmic reticulum membrane reorganization is regulated by ionic homeostasis

PloS one, 2013-02, Vol.8 (2), p.e56603

2013

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Evidence that Ca2+ within the microdomain of the L-type voltage gated Ca2+ channel activates ERK in MIN6 cells in response to glucagon-like peptide-1

PloS one, 2012-03, Vol.7 (3), p.e33004-e33004

2012

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Endothelin-converting enzyme-1 regulates glucagon-like peptide-1 receptor signalling and resensitisation

Biochemical journal, 2019-02, Vol.476 (3), p.513-533

2019

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Mammalian RGS proteins: Multifunctional regulators of cellular signalling

Seminars in cell & developmental biology, 2006-06, Vol.17 (3), p.363-376

Willars, Gary B.

2006

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Elk-1, CREB, and MKP-1 regulate Egr-1 expression in gonadotropin-releasing hormone stimulated gonadotrophs

Journal of cellular biochemistry, 2008-12, Vol.105 (5), p.1267-1278

2008

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Modulation of Glucagon Receptor Pharmacology by Receptor Activity-modifying Protein-2 (RAMP2)

The Journal of biological chemistry, 2015-09, Vol.290 (38), p.23009-23022

2015

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Paradoxical behavior of neuromedin U in isolated smooth muscle cells and intact tissue

The Journal of pharmacology and experimental therapeutics, 2008-04, Vol.325 (1), p.154

2008

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Mechanisms Underlying the Neuronal Calcium Sensor-1-evoked Enhancement of Exocytosis in PC12 Cells

The Journal of biological chemistry, 2002-08, Vol.277 (33), p.30315-30324

2002

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Ligand-Specific Signaling Profiles and Resensitization Mechanisms of the Neuromedin U2 Receptor

Molecular pharmacology, 2018-07, Vol.94 (1), p.674-688

2018

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PERK Activation at Low Glucose Concentration Is Mediated by SERCA Pump Inhibition and Confers Preemptive Cytoprotection to Pancreatic β-Cells

Molecular endocrinology (Baltimore, Md.), 2011-02, Vol.25 (2), p.315-326

2011

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Comparative effects of the endogenous agonist glucagon-like peptide-1 (GLP-1)-(7-36) amide and the small-molecule ago-allosteric agent "compound 2" at the GLP-1 receptor

The Journal of pharmacology and experimental therapeutics, 2010-09, Vol.334 (3), p.795

2010

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Proinsulin C-Peptide Antagonizes the Profibrotic Effects of TGF-β1 via Up-Regulation of Retinoic Acid and HGF-Related Signaling Pathways

Molecular endocrinology (Baltimore, Md.), 2010-04, Vol.24 (4), p.822-831

2010

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C-peptide reverses TGF-β1-induced changes in renal proximal tubular cells: implications for treatment of diabetic nephropathy

American Journal of Physiology - Renal Physiology, 2009-03, Vol.296 (3), p.F614-F621

2009

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British Pharmacological Society, 5th Focused Meeting on Cell Signalling: Matters arising

British journal of pharmacology, 2015-07, Vol.172 (13), p.3194-3195

2015

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Small lipidated anti-obesity compounds derived from neuromedin U

European journal of medicinal chemistry, 2015-08, Vol.101, p.616-626

2015

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C-peptide signals via Gαi to protect against TNF-α-mediated apoptosis of opossum kidney proximal tubular cells

Journal of the American Society of Nephrology, 2006-04, Vol.17 (4), p.986-995

2006

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Characterization of the migration of lung and blood T cells in response CXCL12 in a three‐dimensional matrix

Immunology, 2010-08, Vol.130 (4), p.564-571

2010

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Lack of receptor-selective effects of either RGS2, RGS3 or RGS4 on muscarinic M3-and gonadotropin-releasing hormone receptor-mediated signalling through Gαq/11

European journal of pharmacology, 2008-06, Vol.587 (1-3), p.16-24

2008

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Microarray Analysis Reveals Up-Regulation of Retinoic Acid and Hepatocyte Growth Factor Related Signaling Pathways by Pro-Insulin C-Peptide in Kidney Proximal Tubular Cells: Antagonism of the Pro-Fibrotic Effects of TGF-β1

The journal of clinical endocrinology and metabolism, 2010-03, Vol.95 (3), p.1478-1478

2010

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Allosteric modulation of the activity of the glucagon-like peptide-1 (GLP-1) metabolite GLP-1 9-36 amide at the GLP-1 receptor

Neuromedin U and its receptors: structure, function, and physiological roles

Hazards of Using Masking Protocols When Performing Ligand Binding Assays: Lessons From the Sigma-1 and Sigma-2 Receptors

cAMP inhibits mammalian target of rapamycin complex-1 and -2 (mTORC1 and 2) by promoting complex dissociation and inhibiting mTOR kinase activity

The role of phosphoinositide 3-kinases in neutrophil migration in 3D collagen gels

Mechanisms of cross-talk between G-protein-coupled receptors resulting in enhanced release of intracellular Ca2

Endoplasmic reticulum membrane reorganization is regulated by ionic homeostasis

Evidence that Ca2+ within the microdomain of the L-type voltage gated Ca2+ channel activates ERK in MIN6 cells in response to glucagon-like peptide-1

Endothelin-converting enzyme-1 regulates glucagon-like peptide-1 receptor signalling and resensitisation

Mammalian RGS proteins: Multifunctional regulators of cellular signalling

Elk-1, CREB, and MKP-1 regulate Egr-1 expression in gonadotropin-releasing hormone stimulated gonadotrophs

Modulation of Glucagon Receptor Pharmacology by Receptor Activity-modifying Protein-2 (RAMP2)

Paradoxical behavior of neuromedin U in isolated smooth muscle cells and intact tissue

Mechanisms Underlying the Neuronal Calcium Sensor-1-evoked Enhancement of Exocytosis in PC12 Cells

Ligand-Specific Signaling Profiles and Resensitization Mechanisms of the Neuromedin U2 Receptor

PERK Activation at Low Glucose Concentration Is Mediated by SERCA Pump Inhibition and Confers Preemptive Cytoprotection to Pancreatic β-Cells

Comparative effects of the endogenous agonist glucagon-like peptide-1 (GLP-1)-(7-36) amide and the small-molecule ago-allosteric agent "compound 2" at the GLP-1 receptor

Proinsulin C-Peptide Antagonizes the Profibrotic Effects of TGF-β1 via Up-Regulation of Retinoic Acid and HGF-Related Signaling Pathways

C-peptide reverses TGF-β1-induced changes in renal proximal tubular cells: implications for treatment of diabetic nephropathy

British Pharmacological Society, 5th Focused Meeting on Cell Signalling: Matters arising

Small lipidated anti-obesity compounds derived from neuromedin U

C-peptide signals via Gαi to protect against TNF-α-mediated apoptosis of opossum kidney proximal tubular cells

Characterization of the migration of lung and blood T cells in response CXCL12 in a three‐dimensional matrix

Lack of receptor-selective effects of either RGS2, RGS3 or RGS4 on muscarinic M3-and gonadotropin-releasing hormone receptor-mediated signalling through Gαq/11

Microarray Analysis Reveals Up-Regulation of Retinoic Acid and Hepatocyte Growth Factor Related Signaling Pathways by Pro-Insulin C-Peptide in Kidney Proximal Tubular Cells: Antagonism of the Pro-Fibrotic Effects of TGF-β1

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