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Marine pharmacology in 2018: Marine compounds with antibacterial, antidiabetic, antifungal, anti-inflammatory, antiprotozoal, antituberculosis and antiviral activities; affecting the immune and nervous systems, and other miscellaneous mechanisms of action

Pharmacological research, 2022-09, Vol.183, p.106391-106391, Article 106391

2022

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Isolation, Structural Analysis and Biological Activity Assays of Biselisabethoxanes A and B: Two Dissymmetric Bis -Diterpenes from the Southwestern Caribbean Sea Gorgonian Coral Pseudopterogorgia elisabethae

Molecules (Basel, Switzerland), 2022-11, Vol.27 (22), p.7879

2022

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The Discreet Structural Diversity of Briarellins: DU8+ Guided Multiple Structure Revisions Yielded Two Unknown Structural Types

Journal of organic chemistry, 2020-05, Vol.85 (9), p.6201-6205

2020

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Plakortinic Acids A and B: Cytotoxic Cycloperoxides with a Bicyclo[4.2.0]octene Unit from Sponges of the Genera Plakortis and Xestospongia

Organic letters, 2017-03, Vol.19 (6), p.1486-1489

2017

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Kallopterolides A-I, a New Subclass of seco -Diterpenes Isolated from the Southwestern Caribbean Sea Plume Antillogorgia kallos

Molecules (Basel, Switzerland), 2024-05, Vol.29 (11), p.2493

2024

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Monamphilectine A, a Potent Antimalarial β-Lactam from Marine Sponge Hymeniacidon sp: Isolation, Structure, Semisynthesis, and Bioactivity

Organic letters, 2010-11, Vol.12 (22), p.5290-5293

2010

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Simultaneous structure-activity studies and arming of natural products by C-H amination reveal cellular targets of eupalmerin acetate

Nature chemistry, 2013-06, Vol.5 (6), p.510-517

2013

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Marine pharmacology in 2007–8: Marine compounds with antibacterial, anticoagulant, antifungal, anti-inflammatory, antimalarial, antiprotozoal, antituberculosis, and antiviral activities; affecting the immune and nervous system, and other miscellaneous mechanisms of action

Comparative biochemistry and physiology. Toxicology & pharmacology, 2011-03, Vol.153 (2), p.191-222

2011

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Two Rare-Class Tricyclic Diterpenes with Antitubercular Activity from the Caribbean Sponge Svenzea flava. Application of Vibrational Circular Dichroism Spectroscopy for Determining Absolute Configuration

Journal of organic chemistry, 2013-11, Vol.78 (22), p.11294-11301

2013

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Target-Based Screening against eIF4A1 Reveals the Marine Natural Product Elatol as a Novel Inhibitor of Translation Initiation with In Vivo Antitumor Activity

Clinical cancer research, 2018-09, Vol.24 (17), p.4256-4270

2018

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Probing the Antiplasmodial Properties of Plakortinic Acids C and D: An Uncommon Pair of Marine Peroxide-Polyketides Isolated from a Two-Sponge Association of Plakortis symbiotica and Xetospongia deweerdtae Collected near Puerto Rico

Life (Basel, Switzerland), 2024-06, Vol.14 (6), p.684

2024

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Two Gracilioethers Containing a [2(5H)-Furanylidene]ethanoate Moiety and 9,10-Dihydroplakortone G: New Polyketides from the Caribbean Marine Sponge Plakortis halichondrioides

Applied sciences, 2024-01, Vol.14 (1), p.281

2024

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Dolabellane-Type Diterpenoids with Antiprotozoan Activity from a Southwestern Caribbean Gorgonian Octocoral of the Genus Eunicea

Journal of natural products (Washington, D.C.), 2010-05, Vol.73 (5), p.925-934

2010

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Bioactive Cycloperoxides Isolated from the Puerto Rican Sponge Plakortis halichondrioides

Journal of natural products (Washington, D.C.), 2010-10, Vol.73 (10), p.1694-1700

2010

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Total Synthesis of the Proposed Structure of Briarellin J

Organic letters, 2010-11, Vol.12 (21), p.5028-5031

2010

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Exploring the Sponge Consortium Plakortis symbiotica–Xestospongia deweerdtae as a Potential Source of Antimicrobial Compounds and Probing the Pharmacophore for Antituberculosis Activity of Smenothiazole A by Diverted Total Synthesis

Journal of natural products (Washington, D.C.), 2017-08, Vol.80 (8), p.2295-2303

2017

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ATP-competitive, marine derived natural products that target the DEAD box helicase, eIF4A

Bioorganic & medicinal chemistry letters, 2017-09, Vol.27 (17), p.4082-4085

2017

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Identification of the Binding of Sceptrin to MreB via a Bidirectional Affinity Protocol

Journal of the American Chemical Society, 2008-06, Vol.130 (23), p.7256-7258

2008

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Aberrarone: A Gorgonian-Derived Diterpene from Pseudopterogorgia elisabethae

Journal of organic chemistry, 2009-10, Vol.74 (19), p.7581-7584

2009

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Synthesis and preliminary biological evaluation of a small library of hybrid compounds based on Ugi isocyanide multicomponent reactions with a marine natural product scaffold

Bioorganic & medicinal chemistry letters, 2015-11, Vol.25 (22), p.5339-5343

2015

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Corallolides A and B: Bioactive Diterpenes Featuring a Novel Carbon Skeleton

Organic letters, 2009-08, Vol.11 (16), p.3786-3789

2009

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Bipinnatins K–Q, Minor Cembrane-Type Diterpenes from the West Indian Gorgonian Pseudopterogorgia kallos: Isolation, Structure Assignment, and Evaluation of Biological Activities

Journal of natural products (Washington, D.C.), 2008-03, Vol.71 (3), p.381-389

2008

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Eupalmerin acetate, a novel anticancer agent from Caribbean gorgonian octocorals, induces apoptosis in malignant glioma cells via the c-Jun NH2-terminal kinase pathway

Molecular cancer therapeutics, 2007-01, Vol.6 (1), p.184-192

2007

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Caribenols A and B, Sea Whip Derived Norditerpenes with Novel Tricarbocyclic Skeletons

Journal of organic chemistry, 2007-09, Vol.72 (19), p.7386-7389

2007

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Bioactive Compounds from the Gorgonian Briareum polyanthes. Correction of the Structures of Four Asbestinane-Type Diterpenes

Journal of natural products (Washington, D.C.), 2006-12, Vol.69 (12), p.1721-1727

2006

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Marine pharmacology in 2018: Marine compounds with antibacterial, antidiabetic, antifungal, anti-inflammatory, antiprotozoal, antituberculosis and antiviral activities; affecting the immune and nervous systems, and other miscellaneous mechanisms of action

Isolation, Structural Analysis and Biological Activity Assays of Biselisabethoxanes A and B: Two Dissymmetric Bis -Diterpenes from the Southwestern Caribbean Sea Gorgonian Coral Pseudopterogorgia elisabethae

The Discreet Structural Diversity of Briarellins: DU8+ Guided Multiple Structure Revisions Yielded Two Unknown Structural Types

Plakortinic Acids A and B: Cytotoxic Cycloperoxides with a Bicyclo[4.2.0]octene Unit from Sponges of the Genera Plakortis and Xestospongia

Kallopterolides A-I, a New Subclass of seco -Diterpenes Isolated from the Southwestern Caribbean Sea Plume Antillogorgia kallos

Monamphilectine A, a Potent Antimalarial β-Lactam from Marine Sponge Hymeniacidon sp: Isolation, Structure, Semisynthesis, and Bioactivity

Simultaneous structure-activity studies and arming of natural products by C-H amination reveal cellular targets of eupalmerin acetate

Marine pharmacology in 2007–8: Marine compounds with antibacterial, anticoagulant, antifungal, anti-inflammatory, antimalarial, antiprotozoal, antituberculosis, and antiviral activities; affecting the immune and nervous system, and other miscellaneous mechanisms of action

Two Rare-Class Tricyclic Diterpenes with Antitubercular Activity from the Caribbean Sponge Svenzea flava. Application of Vibrational Circular Dichroism Spectroscopy for Determining Absolute Configuration

Target-Based Screening against eIF4A1 Reveals the Marine Natural Product Elatol as a Novel Inhibitor of Translation Initiation with In Vivo Antitumor Activity

Probing the Antiplasmodial Properties of Plakortinic Acids C and D: An Uncommon Pair of Marine Peroxide-Polyketides Isolated from a Two-Sponge Association of Plakortis symbiotica and Xetospongia deweerdtae Collected near Puerto Rico

Two Gracilioethers Containing a [2(5H)-Furanylidene]ethanoate Moiety and 9,10-Dihydroplakortone G: New Polyketides from the Caribbean Marine Sponge Plakortis halichondrioides

Dolabellane-Type Diterpenoids with Antiprotozoan Activity from a Southwestern Caribbean Gorgonian Octocoral of the Genus Eunicea

Bioactive Cycloperoxides Isolated from the Puerto Rican Sponge Plakortis halichondrioides

Total Synthesis of the Proposed Structure of Briarellin J

Exploring the Sponge Consortium Plakortis symbiotica–Xestospongia deweerdtae as a Potential Source of Antimicrobial Compounds and Probing the Pharmacophore for Antituberculosis Activity of Smenothiazole A by Diverted Total Synthesis

ATP-competitive, marine derived natural products that target the DEAD box helicase, eIF4A

Identification of the Binding of Sceptrin to MreB via a Bidirectional Affinity Protocol

Aberrarone: A Gorgonian-Derived Diterpene from Pseudopterogorgia elisabethae

Synthesis and preliminary biological evaluation of a small library of hybrid compounds based on Ugi isocyanide multicomponent reactions with a marine natural product scaffold

Corallolides A and B: Bioactive Diterpenes Featuring a Novel Carbon Skeleton

Bipinnatins K–Q, Minor Cembrane-Type Diterpenes from the West Indian Gorgonian Pseudopterogorgia kallos: Isolation, Structure Assignment, and Evaluation of Biological Activities

Eupalmerin acetate, a novel anticancer agent from Caribbean gorgonian octocorals, induces apoptosis in malignant glioma cells via the c-Jun NH2-terminal kinase pathway

Caribenols A and B, Sea Whip Derived Norditerpenes with Novel Tricarbocyclic Skeletons

Bioactive Compounds from the Gorgonian Briareum polyanthes. Correction of the Structures of Four Asbestinane-Type Diterpenes

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