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Mechanism and relevance of EWS/FLI-mediated transcriptional repression in Ewing sarcoma

Oncogene, 2013-10, Vol.32 (42), p.5089-5100

2013

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A novel tyrosine kinase switch is a mechanism of imatinib resistance in gastrointestinal stromal tumors

Oncogene, 2007-06, Vol.26 (27), p.3909-3919

2007

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Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription

Proceedings of the National Academy of Sciences - PNAS, 2002-09, Vol.99 (18), p.11593-11598

2002

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Mechanism and relevance of EWS/FLI-mediated transcriptional repression in Ewing sarcoma

Oncogene, 2016-11, Vol.35 (47), p.6155-6156

2016

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Different expression of placental pyruvate kinase in normal, preeclamptic and intrauterine growth restriction pregnancies

Placenta (Eastbourne), 2014-11, Vol.35 (11), p.883-890

2014

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P-411 Pancreatic cancer oral inverse agonist of RORgT receptor targets primary cancer cells and alters inflammatory mediators of the tumor microenvironment

Annals of oncology, 2023-06, Vol.34, p.S157-S157

2023

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Transcriptional Repression by YY1 is Mediated by Interaction with a Mammalian Homolog of the Yeast Global Regulator RPD3

Proceedings of the National Academy of Sciences - PNAS, 1996-11, Vol.93 (23), p.12845-12850

1996

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Targeting PIM kinase enhances the activity of sunitinib in renal cell carcinoma

British journal of cancer, 2011-11, Vol.105 (10), p.1563-1573

2011

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Sensitization of a Glioblastoma Multiforme (GBM) Cell Line by MP470: A Novel c-Met Antagonist

International journal of radiation oncology, biology, physics, 2007-11, Vol.69 (3), p.S100-S100

2007

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Mutations in the G-Quadruplex Silencer Element and Their Relationship to c-MYC Overexpression, NM23 Repression, and Therapeutic Rescue

Proceedings of the National Academy of Sciences - PNAS, 2004-04, Vol.101 (16), p.6140-6145

2004

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Reciprocal regulation of neu tyrosine kinase activity and caveolin-1 protein expression in vitro and in vivo. Implications for human breast cancer

The Journal of biological chemistry, 1998-08, Vol.273 (32), p.20448-20455

1998

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Telomere maintenance mechanisms as a target for drug development

Oncogene, 2000-12, Vol.19 (56), p.6632-6641

2000

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A Farnesyltransferase Inhibitor Induces Tumor Regression in Transgenic Mice Harboring Multiple Oncogenic Mutations by Mediating Alterations in Both Cell Cycle Control and Apoptosis

Molecular and Cellular Biology, 1998-01, Vol.18 (1), p.85-92

1998

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Genetic determinants of response to chemotherapy in transgenic mouse mammary and salivary tumors

Oncogene, 2000-02, Vol.19 (8), p.1114-1122

2000

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Erratum: Mechanism and relevance of EWS/FLI-mediated transcriptional repression in Ewing sarcoma

Oncogene, 2016-11, Vol.35 (47), p.6155-6156

2016

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460PA phase Ia/b first-in-human, open-label, dose-escalation, safety, PK and PD study of TP-0903 in solid tumours

Annals of oncology, 2019-10, Vol.30 (Supplement_5)

2019

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Laminin-5 beta 3A Expression in LNCaP Human Prostate Carcinoma Cells Increases Cell Migration and Tumorigenicity

Neoplasia (New York, N.Y.), 2004-10, Vol.6 (5), p.468-479

2004

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332 POSTER In vivo activity of SGI-1776, an orally active Pim kinase inhibitor

European journal of cancer supplements, 2008, Vol.6 (12), p.105-106

2008

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341 Targeting NEK2 kinase in drug resistant multiple myeloma with small molecule inhibitors

European journal of cancer supplements, 2010, Vol.8 (7), p.109-109

2010

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PF285 ZELLA‐101: PHASE 1 STUDY OF ALVOCIDIB FOLLOWED BY 7+3 INDUCTION IN NEWLY DIAGNOSED AML PATIENTS

HemaSphere, 2019-06, Vol.3 (S1), p.94-n/a

2019

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Identification of differentially expressed genes in pancreatic cancer cells using cDNA microarray

Cancer research (Chicago, Ill.), 2002-05, Vol.62 (10), p.2890-2896

2002

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The cationic porphyrin TMPyP4 down-regulates c-MYC and human telomerase reverse transcriptase expression and inhibits tumor growth in vivo

Molecular cancer therapeutics, 2002-06, Vol.1 (8), p.565-573

2002

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Abstract P2-06-05: TP-0903, an AXL kinase inhibitor, reduces inflammatory breast cancer aggressiveness and macrophage polarization through additional mechanisms that may include JAK2 and Aurora B

Cancer research (Chicago, Ill.), 2019-02, Vol.79 (4_Supplement), p.P2-P2-06-05

2019

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Telomere inhibition and telomere disruption as processes for drug targeting

Annual review of pharmacology and toxicology, 2003-01, Vol.43 (1), p.359-379

2003

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Aurora-A over-expression in high-grade PIN lesions and prostate cancer

The Prostate, 2005-09, Vol.64 (4), p.341-346

2005

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Mechanism and relevance of EWS/FLI-mediated transcriptional repression in Ewing sarcoma

A novel tyrosine kinase switch is a mechanism of imatinib resistance in gastrointestinal stromal tumors

Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription

Mechanism and relevance of EWS/FLI-mediated transcriptional repression in Ewing sarcoma

Different expression of placental pyruvate kinase in normal, preeclamptic and intrauterine growth restriction pregnancies

P-411 Pancreatic cancer oral inverse agonist of RORgT receptor targets primary cancer cells and alters inflammatory mediators of the tumor microenvironment

Transcriptional Repression by YY1 is Mediated by Interaction with a Mammalian Homolog of the Yeast Global Regulator RPD3

Targeting PIM kinase enhances the activity of sunitinib in renal cell carcinoma

Sensitization of a Glioblastoma Multiforme (GBM) Cell Line by MP470: A Novel c-Met Antagonist

Mutations in the G-Quadruplex Silencer Element and Their Relationship to c-MYC Overexpression, NM23 Repression, and Therapeutic Rescue

Reciprocal regulation of neu tyrosine kinase activity and caveolin-1 protein expression in vitro and in vivo. Implications for human breast cancer

Telomere maintenance mechanisms as a target for drug development

A Farnesyltransferase Inhibitor Induces Tumor Regression in Transgenic Mice Harboring Multiple Oncogenic Mutations by Mediating Alterations in Both Cell Cycle Control and Apoptosis

Genetic determinants of response to chemotherapy in transgenic mouse mammary and salivary tumors

Erratum: Mechanism and relevance of EWS/FLI-mediated transcriptional repression in Ewing sarcoma

460PA phase Ia/b first-in-human, open-label, dose-escalation, safety, PK and PD study of TP-0903 in solid tumours

Laminin-5 beta 3A Expression in LNCaP Human Prostate Carcinoma Cells Increases Cell Migration and Tumorigenicity

332 POSTER In vivo activity of SGI-1776, an orally active Pim kinase inhibitor

341 Targeting NEK2 kinase in drug resistant multiple myeloma with small molecule inhibitors

PF285 ZELLA‐101: PHASE 1 STUDY OF ALVOCIDIB FOLLOWED BY 7+3 INDUCTION IN NEWLY DIAGNOSED AML PATIENTS

Identification of differentially expressed genes in pancreatic cancer cells using cDNA microarray

The cationic porphyrin TMPyP4 down-regulates c-MYC and human telomerase reverse transcriptase expression and inhibits tumor growth in vivo

Abstract P2-06-05: TP-0903, an AXL kinase inhibitor, reduces inflammatory breast cancer aggressiveness and macrophage polarization through additional mechanisms that may include JAK2 and Aurora B

Telomere inhibition and telomere disruption as processes for drug targeting

Aurora-A over-expression in high-grade PIN lesions and prostate cancer

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